{
  "url": "https://dantelabs.com/traits/optic-nerve-misrouting",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "optic-nerve-misrouting",
    "id": "HP:0025551",
    "name": "Optic nerve misrouting",
    "definition": "Abnormal decussation of the visual pathways, typically identified using visual evoked potentials (VEP) (asymmetrical distribution of the VEP over the posterior scalp).",
    "synonyms": [
      "Optic pathway misrouting",
      "Visual pathway misrouting"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-optic-nerve-morphology",
        "name": "Optic nerve issue",
        "url": "https://dantelabs.com/traits/abnormal-optic-nerve-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "mc1r",
        "symbol": "MC1R",
        "hgnc": "HGNC:6929",
        "name": "melanocortin 1 receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mc1r"
      },
      {
        "slug": "oca2",
        "symbol": "OCA2",
        "hgnc": "HGNC:8101",
        "name": "OCA2 melanosomal transmembrane protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/oca2"
      },
      {
        "slug": "slc45a2",
        "symbol": "SLC45A2",
        "hgnc": "HGNC:16472",
        "name": "solute carrier family 45 member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc45a2"
      },
      {
        "slug": "tyrp1",
        "symbol": "TYRP1",
        "hgnc": "HGNC:12450",
        "name": "tyrosinase related protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyrp1"
      },
      {
        "slug": "slc38a8",
        "symbol": "SLC38A8",
        "hgnc": "HGNC:32434",
        "name": "solute carrier family 38 member 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc38a8"
      }
    ]
  }
}