{
  "url": "https://dantelabs.com/traits/joint-subluxation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "joint-subluxation",
    "id": "HP:0032153",
    "name": "Joint subluxation",
    "definition": "A partial dislocation of a joint.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-joint-morphology",
        "name": "Abnormal shape of joints",
        "url": "https://dantelabs.com/traits/abnormal-joint-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "radial-head-subluxation",
        "name": "Radial head subluxation",
        "genes": 9,
        "url": "https://dantelabs.com/traits/radial-head-subluxation"
      },
      {
        "slug": "cervical-subluxation",
        "name": "Cervical subluxation",
        "genes": 3,
        "url": "https://dantelabs.com/traits/cervical-subluxation"
      },
      {
        "slug": "shoulder-subluxation",
        "name": "Partial shoulder dislocation",
        "genes": 3,
        "url": "https://dantelabs.com/traits/shoulder-subluxation"
      },
      {
        "slug": "recurrent-mandibular-subluxations",
        "name": "Recurrent mandibular subluxations",
        "genes": 1,
        "url": "https://dantelabs.com/traits/recurrent-mandibular-subluxations"
      }
    ],
    "genes": [
      {
        "slug": "ifih1",
        "symbol": "IFIH1",
        "hgnc": "HGNC:18873",
        "name": "interferon induced with helicase C domain 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifih1"
      },
      {
        "slug": "col5a1",
        "symbol": "COL5A1",
        "hgnc": "HGNC:2209",
        "name": "collagen type V alpha 1 chain",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col5a1"
      },
      {
        "slug": "efemp2",
        "symbol": "EFEMP2",
        "hgnc": "HGNC:3219",
        "name": "EGF-like fibulin extracellular matrix protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efemp2"
      },
      {
        "slug": "fbln5",
        "symbol": "FBLN5",
        "hgnc": "HGNC:3602",
        "name": "fibulin 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbln5"
      },
      {
        "slug": "ltbp1",
        "symbol": "LTBP1",
        "hgnc": "HGNC:6714",
        "name": "latent transforming growth factor beta binding protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp1"
      },
      {
        "slug": "plod1",
        "symbol": "PLOD1",
        "hgnc": "HGNC:9081",
        "name": "procollagen-lysine,2-oxoglutarate 5-dioxygenase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plod1"
      },
      {
        "slug": "tnxb",
        "symbol": "TNXB",
        "hgnc": "HGNC:11976",
        "name": "tenascin XB",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnxb"
      },
      {
        "slug": "rigi",
        "symbol": "RIGI",
        "hgnc": "HGNC:19102",
        "name": "RNA sensor RIG-I",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rigi"
      },
      {
        "slug": "col1a1",
        "symbol": "COL1A1",
        "hgnc": "HGNC:2197",
        "name": "collagen type I alpha 1 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a1"
      },
      {
        "slug": "col1a2",
        "symbol": "COL1A2",
        "hgnc": "HGNC:2198",
        "name": "collagen type I alpha 2 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a2"
      }
    ]
  }
}