{
  "url": "https://dantelabs.com/traits/hyperlipoproteinemia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperlipoproteinemia",
    "id": "HP:0010980",
    "name": "Hyperlipoproteinemia",
    "definition": "An abnormal increase in the level of lipoprotein cholesterol in the blood.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-lipoprotein-cholesterol-concentration",
        "name": "Abnormal circulating lipoprotein cholesterol concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-lipoprotein-cholesterol-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "elevated-circulating-ldl-c-concentration",
        "name": "Increased circulating LDL level",
        "genes": 33,
        "url": "https://dantelabs.com/traits/elevated-circulating-ldl-c-concentration"
      },
      {
        "slug": "elevated-circulating-vldl-c-concentration",
        "name": "Elevated circulating VLDL-C concentration",
        "genes": 5,
        "url": "https://dantelabs.com/traits/elevated-circulating-vldl-c-concentration"
      },
      {
        "slug": "increased-circulating-chylomicron-concentration",
        "name": "Increased circulating chylomicron concentration",
        "genes": 4,
        "url": "https://dantelabs.com/traits/increased-circulating-chylomicron-concentration"
      },
      {
        "slug": "elevated-circulating-hdl-c-concentration",
        "name": "High blood HDL level",
        "genes": 3,
        "url": "https://dantelabs.com/traits/elevated-circulating-hdl-c-concentration"
      }
    ],
    "genes": [
      {
        "slug": "gpihbp1",
        "symbol": "GPIHBP1",
        "hgnc": "HGNC:24945",
        "name": "glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpihbp1"
      }
    ]
  }
}