{
  "url": "https://dantelabs.com/traits/complete-right-bundle-branch-block",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "complete-right-bundle-branch-block",
    "id": "HP:0011712",
    "name": "Complete right bundle branch block",
    "definition": "A conduction block of the right branch of the bundle of His. This manifests as a prolongation of the QRS complex (greater than 0.12 s) with delayed activation of the right ventricle and terminal delay on the EKG.",
    "synonyms": [
      "Right bundle branch block",
      "Right bundle-branch block"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "bundle-branch-block",
        "name": "Bundle branch block",
        "url": "https://dantelabs.com/traits/bundle-branch-block"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "banf1",
        "symbol": "BANF1",
        "hgnc": "HGNC:17397",
        "name": "barrier to autointegration nuclear assembly factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/banf1"
      },
      {
        "slug": "cnbp",
        "symbol": "CNBP",
        "hgnc": "HGNC:13164",
        "name": "CCHC-type zinc finger nucleic acid binding protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnbp"
      },
      {
        "slug": "exosc5",
        "symbol": "EXOSC5",
        "hgnc": "HGNC:24662",
        "name": "exosome component 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/exosc5"
      },
      {
        "slug": "gyg1",
        "symbol": "GYG1",
        "hgnc": "HGNC:4699",
        "name": "glycogenin 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gyg1"
      },
      {
        "slug": "hcn4",
        "symbol": "HCN4",
        "hgnc": "HGNC:16882",
        "name": "hyperpolarization activated cyclic nucleotide gated potassium channel 4",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hcn4"
      },
      {
        "slug": "lmod2",
        "symbol": "LMOD2",
        "hgnc": "HGNC:6648",
        "name": "leiomodin 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmod2"
      },
      {
        "slug": "myh6",
        "symbol": "MYH6",
        "hgnc": "HGNC:7576",
        "name": "myosin heavy chain 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh6"
      },
      {
        "slug": "pomt2",
        "symbol": "POMT2",
        "hgnc": "HGNC:19743",
        "name": "protein O-mannosyltransferase 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pomt2"
      },
      {
        "slug": "tnnc1",
        "symbol": "TNNC1",
        "hgnc": "HGNC:11943",
        "name": "troponin C1, slow skeletal and cardiac type",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnnc1"
      },
      {
        "slug": "abcc9",
        "symbol": "ABCC9",
        "hgnc": "HGNC:60",
        "name": "ATP binding cassette subfamily C member 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abcc9"
      },
      {
        "slug": "akap9",
        "symbol": "AKAP9",
        "hgnc": "HGNC:379",
        "name": "A-kinase anchoring protein 9",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akap9"
      },
      {
        "slug": "cacna1c",
        "symbol": "CACNA1C",
        "hgnc": "HGNC:1390",
        "name": "calcium voltage-gated channel subunit alpha1 C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1c"
      },
      {
        "slug": "cacna2d1",
        "symbol": "CACNA2D1",
        "hgnc": "HGNC:1399",
        "name": "calcium voltage-gated channel auxiliary subunit alpha2delta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna2d1"
      },
      {
        "slug": "cacnb2",
        "symbol": "CACNB2",
        "hgnc": "HGNC:1402",
        "name": "calcium voltage-gated channel auxiliary subunit beta 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacnb2"
      },
      {
        "slug": "dnmt3b",
        "symbol": "DNMT3B",
        "hgnc": "HGNC:2979",
        "name": "DNA methyltransferase 3 beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnmt3b"
      },
      {
        "slug": "dux4",
        "symbol": "DUX4",
        "hgnc": "HGNC:50800",
        "name": "double homeobox 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dux4"
      },
      {
        "slug": "dux4l1",
        "symbol": "DUX4L1",
        "hgnc": "HGNC:3082",
        "name": "double homeobox 4 like 1 (pseudogene)",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dux4l1"
      },
      {
        "slug": "frg1",
        "symbol": "FRG1",
        "hgnc": "HGNC:3954",
        "name": "FSHD region gene 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/frg1"
      },
      {
        "slug": "gpd1l",
        "symbol": "GPD1L",
        "hgnc": "HGNC:28956",
        "name": "glycerol-3-phosphate dehydrogenase 1 like",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gpd1l"
      },
      {
        "slug": "kcnd3",
        "symbol": "KCND3",
        "hgnc": "HGNC:6239",
        "name": "potassium voltage-gated channel subfamily D member 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnd3"
      },
      {
        "slug": "kcne3",
        "symbol": "KCNE3",
        "hgnc": "HGNC:6243",
        "name": "potassium voltage-gated channel subfamily E regulatory subunit 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcne3"
      },
      {
        "slug": "kcne5",
        "symbol": "KCNE5",
        "hgnc": "HGNC:6241",
        "name": "potassium voltage-gated channel subfamily E regulatory subunit 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcne5"
      },
      {
        "slug": "kcnj8",
        "symbol": "KCNJ8",
        "hgnc": "HGNC:6269",
        "name": "potassium inwardly rectifying channel subfamily J member 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj8"
      },
      {
        "slug": "lemd2",
        "symbol": "LEMD2",
        "hgnc": "HGNC:21244",
        "name": "LEM domain nuclear envelope protein 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lemd2"
      },
      {
        "slug": "myh7",
        "symbol": "MYH7",
        "hgnc": "HGNC:7577",
        "name": "myosin heavy chain 7",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/myh7"
      },
      {
        "slug": "nppa",
        "symbol": "NPPA",
        "hgnc": "HGNC:7939",
        "name": "natriuretic peptide A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nppa"
      },
      {
        "slug": "pkp2",
        "symbol": "PKP2",
        "hgnc": "HGNC:9024",
        "name": "plakophilin 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pkp2"
      },
      {
        "slug": "ppp1cb",
        "symbol": "PPP1CB",
        "hgnc": "HGNC:9282",
        "name": "protein phosphatase 1 catalytic subunit beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp1cb"
      },
      {
        "slug": "rangrf",
        "symbol": "RANGRF",
        "hgnc": "HGNC:17679",
        "name": "RAN guanine nucleotide release factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rangrf"
      },
      {
        "slug": "scn10a",
        "symbol": "SCN10A",
        "hgnc": "HGNC:10582",
        "name": "sodium voltage-gated channel alpha subunit 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn10a"
      },
      {
        "slug": "scn1b",
        "symbol": "SCN1B",
        "hgnc": "HGNC:10586",
        "name": "sodium voltage-gated channel beta subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn1b"
      },
      {
        "slug": "scn2b",
        "symbol": "SCN2B",
        "hgnc": "HGNC:10589",
        "name": "sodium voltage-gated channel beta subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn2b"
      },
      {
        "slug": "scn3b",
        "symbol": "SCN3B",
        "hgnc": "HGNC:20665",
        "name": "sodium voltage-gated channel beta subunit 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn3b"
      },
      {
        "slug": "scn5a",
        "symbol": "SCN5A",
        "hgnc": "HGNC:10593",
        "name": "sodium voltage-gated channel alpha subunit 5",
        "frequency": "frequent",
        "diseases": 5,
        "url": "https://dantelabs.com/genes/scn5a"
      },
      {
        "slug": "scnn1a",
        "symbol": "SCNN1A",
        "hgnc": "HGNC:10599",
        "name": "sodium channel epithelial 1 subunit alpha",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scnn1a"
      },
      {
        "slug": "sema3a",
        "symbol": "SEMA3A",
        "hgnc": "HGNC:10723",
        "name": "semaphorin 3A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema3a"
      },
      {
        "slug": "slmap",
        "symbol": "SLMAP",
        "hgnc": "HGNC:16643",
        "name": "sarcolemma associated protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slmap"
      },
      {
        "slug": "smchd1",
        "symbol": "SMCHD1",
        "hgnc": "HGNC:29090",
        "name": "structural maintenance of chromosomes flexible hinge domain containing 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/smchd1"
      },
      {
        "slug": "tll1",
        "symbol": "TLL1",
        "hgnc": "HGNC:11843",
        "name": "tolloid like 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tll1"
      },
      {
        "slug": "trpm4",
        "symbol": "TRPM4",
        "hgnc": "HGNC:17993",
        "name": "transient receptor potential cation channel subfamily M member 4",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trpm4"
      },
      {
        "slug": "actc1",
        "symbol": "ACTC1",
        "hgnc": "HGNC:143",
        "name": "actin alpha cardiac muscle 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actc1"
      },
      {
        "slug": "cited2",
        "symbol": "CITED2",
        "hgnc": "HGNC:1987",
        "name": "Cbp/p300 interacting transactivator with ED-rich tail 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cited2"
      },
      {
        "slug": "dsg2",
        "symbol": "DSG2",
        "hgnc": "HGNC:3049",
        "name": "desmoglein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dsg2"
      },
      {
        "slug": "dysf",
        "symbol": "DYSF",
        "hgnc": "HGNC:3097",
        "name": "dysferlin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dysf"
      },
      {
        "slug": "fhl1",
        "symbol": "FHL1",
        "hgnc": "HGNC:3702",
        "name": "four and a half LIM domains 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fhl1"
      },
      {
        "slug": "flnc",
        "symbol": "FLNC",
        "hgnc": "HGNC:3756",
        "name": "filamin C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnc"
      },
      {
        "slug": "kcnk3",
        "symbol": "KCNK3",
        "hgnc": "HGNC:6278",
        "name": "potassium two pore domain channel subfamily K member 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnk3"
      },
      {
        "slug": "mt-cyb",
        "symbol": "MT-CYB",
        "hgnc": "HGNC:7427",
        "name": "mitochondrially encoded cytochrome b",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mt-cyb"
      },
      {
        "slug": "pigu",
        "symbol": "PIGU",
        "hgnc": "HGNC:15791",
        "name": "phosphatidylinositol glycan anchor biosynthesis class U",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigu"
      },
      {
        "slug": "rnaseh1",
        "symbol": "RNASEH1",
        "hgnc": "HGNC:18466",
        "name": "ribonuclease H1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnaseh1"
      },
      {
        "slug": "sox17",
        "symbol": "SOX17",
        "hgnc": "HGNC:18122",
        "name": "SRY-box transcription factor 17",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox17"
      },
      {
        "slug": "tnnt2",
        "symbol": "TNNT2",
        "hgnc": "HGNC:11949",
        "name": "troponin T2, cardiac type",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnnt2"
      },
      {
        "slug": "plec",
        "symbol": "PLEC",
        "hgnc": "HGNC:9069",
        "name": "plectin",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plec"
      },
      {
        "slug": "atp6v1e1",
        "symbol": "ATP6V1E1",
        "hgnc": "HGNC:857",
        "name": "ATPase H+ transporting V1 subunit E1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1e1"
      },
      {
        "slug": "gnai2",
        "symbol": "GNAI2",
        "hgnc": "HGNC:4385",
        "name": "G protein subunit alpha i2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnai2"
      },
      {
        "slug": "jup",
        "symbol": "JUP",
        "hgnc": "HGNC:6207",
        "name": "junction plakoglobin",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jup"
      },
      {
        "slug": "mybpc3",
        "symbol": "MYBPC3",
        "hgnc": "HGNC:7551",
        "name": "myosin binding protein C3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mybpc3"
      },
      {
        "slug": "tnni3k",
        "symbol": "TNNI3K",
        "hgnc": "HGNC:19661",
        "name": "TNNI3 interacting kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnni3k"
      }
    ]
  }
}