{
  "url": "https://dantelabs.com/traits/comedonal-acne",
  "trait": {
    "bundleId": "2026.10.18-e609d43e",
    "release": "2026-09-01",
    "slug": "comedonal-acne",
    "id": "HP:0040137",
    "name": "Comedonal acne",
    "definition": "A type of acne in which open and closed comedones comprise the majority of the lesions, with substantially fewer papules and pustules.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "acne",
        "name": "Acne",
        "url": "https://dantelabs.com/traits/acne"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "rbp4",
        "symbol": "RBP4",
        "hgnc": "HGNC:9922",
        "name": "retinol binding protein 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbp4"
      }
    ]
  }
}