{
  "url": "https://dantelabs.com/traits/bowed-humerus",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "bowed-humerus",
    "id": "HP:0003865",
    "name": "Bowed long bone in upper arm",
    "label": "Bowed humerus",
    "definition": "A bending or abnormal curvature of the humerus.",
    "synonyms": [
      "Bowing of the humerus",
      "Humeral bowing"
    ],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-humerus-morphology",
        "name": "Abnormal humerus morphology",
        "url": "https://dantelabs.com/traits/abnormal-humerus-morphology"
      },
      {
        "slug": "bowing-of-the-arm",
        "name": "Bowing of the arm",
        "url": "https://dantelabs.com/traits/bowing-of-the-arm"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "b3galt6",
        "symbol": "B3GALT6",
        "hgnc": "HGNC:17978",
        "name": "beta-1,3-galactosyltransferase 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b3galt6"
      },
      {
        "slug": "lbr",
        "symbol": "LBR",
        "hgnc": "HGNC:6518",
        "name": "lamin B receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lbr"
      },
      {
        "slug": "lama5",
        "symbol": "LAMA5",
        "hgnc": "HGNC:6485",
        "name": "laminin subunit alpha 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lama5"
      },
      {
        "slug": "sparc",
        "symbol": "SPARC",
        "hgnc": "HGNC:11219",
        "name": "secreted protein acidic and cysteine rich",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sparc"
      },
      {
        "slug": "kiaa0753",
        "symbol": "KIAA0753",
        "hgnc": "HGNC:29110",
        "name": "KIAA0753",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0753"
      },
      {
        "slug": "rspo2",
        "symbol": "RSPO2",
        "hgnc": "HGNC:28583",
        "name": "R-spondin 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rspo2"
      },
      {
        "slug": "ccn2",
        "symbol": "CCN2",
        "hgnc": "HGNC:2500",
        "name": "cellular communication network factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccn2"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "rnu4atac",
        "symbol": "RNU4ATAC",
        "hgnc": "HGNC:34016",
        "name": "RNA, U4atac small nuclear",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4atac"
      }
    ]
  }
}