{
  "url": "https://dantelabs.com/traits/abnormal-optic-chiasm-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-optic-chiasm-morphology",
    "id": "HP:0025163",
    "name": "Abnormal optic chiasm morphology",
    "definition": "A structural abnormality of the optic chiasm.The optic chiasm, located below the hypothalamus, is a partial crossing of the optic nerves.",
    "synonyms": [
      "Abnormality of optic chiasm morphology"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-optic-nerve-morphology",
        "name": "Optic nerve issue",
        "url": "https://dantelabs.com/traits/abnormal-optic-nerve-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "hypoplastic-optic-chiasm",
        "name": "Hypoplastic optic chiasm",
        "genes": 7,
        "url": "https://dantelabs.com/traits/hypoplastic-optic-chiasm"
      },
      {
        "slug": "opto-chiasmatic-atrophy",
        "name": "Opto-chiasmatic atrophy",
        "genes": 2,
        "url": "https://dantelabs.com/traits/opto-chiasmatic-atrophy"
      }
    ],
    "genes": [
      {
        "slug": "dyrk1a",
        "symbol": "DYRK1A",
        "hgnc": "HGNC:3091",
        "name": "dual specificity tyrosine phosphorylation regulated kinase 1A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dyrk1a"
      }
    ]
  }
}