{
  "url": "https://dantelabs.com/traits/abnormal-circulating-beta-ctx-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-beta-ctx-concentration",
    "id": "HP:0031424",
    "name": "Abnormal circulating beta-CTX concentration",
    "definition": "Any deviation from the normal concentration of beta-CTX (= beta-C-terminal telopeptide, = beta-C-terminal telopeptide of type I collagen) in the blood circulation.",
    "synonyms": [
      "Abnormal circulating beta-C-terminal telopeptide level",
      "Abnormal circulating beta-CrossLaps level",
      "Abnormal circulating beta-CTx level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-protein-concentration",
        "name": "Blood protein disease",
        "url": "https://dantelabs.com/traits/abnormal-circulating-protein-concentration"
      }
    ],
    "narrower": [
      {
        "slug": "elevated-circulating-beta-ctx-concentration",
        "name": "Elevated circulating beta-CTX concentration",
        "genes": 4,
        "url": "https://dantelabs.com/traits/elevated-circulating-beta-ctx-concentration"
      }
    ],
    "genes": [
      {
        "slug": "npr2",
        "symbol": "NPR2",
        "hgnc": "HGNC:7944",
        "name": "natriuretic peptide receptor 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/npr2"
      }
    ]
  }
}