{
  "url": "https://dantelabs.com/es/genes/smg6",
  "gene": {
    "slug": "smg6",
    "symbol": "SMG6",
    "name": "SMG6 nonsense mediated mRNA decay factor",
    "hgnc": "HGNC:17809",
    "summary": null,
    "location": "17p13.3",
    "locusType": "gene with protein product",
    "aliases": [
      "KIAA0732",
      "SMG-6",
      "EST1A"
    ],
    "previousSymbols": [
      "C17orf31"
    ],
    "ensemblId": "ENSG00000070366",
    "entrezId": 23293,
    "omim": [
      "610963"
    ],
    "uniprot": [
      "Q86US8"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 2059843,
      "end": 2303785,
      "strand": "-",
      "ensemblTranscript": "ENST00000263073.11",
      "refseqTranscript": "NM_017575.5",
      "ensemblProtein": "ENSP00000263073.5",
      "refseqProtein": "NP_060045.4",
      "exons": [
        {
          "start": 2059843,
          "end": 2061622
        },
        {
          "start": 2065073,
          "end": 2065154
        },
        {
          "start": 2065468,
          "end": 2065679
        },
        {
          "start": 2068778,
          "end": 2068931
        },
        {
          "start": 2081810,
          "end": 2081956
        },
        {
          "start": 2085725,
          "end": 2085901
        },
        {
          "start": 2172658,
          "end": 2172859
        },
        {
          "start": 2186663,
          "end": 2186831
        },
        {
          "start": 2188399,
          "end": 2188515
        },
        {
          "start": 2236492,
          "end": 2236637
        },
        {
          "start": 2244658,
          "end": 2244719
        },
        {
          "start": 2282647,
          "end": 2282859
        },
        {
          "start": 2283625,
          "end": 2283735
        },
        {
          "start": 2292552,
          "end": 2292630
        },
        {
          "start": 2292871,
          "end": 2292977
        },
        {
          "start": 2297243,
          "end": 2297353
        },
        {
          "start": 2297863,
          "end": 2298055
        },
        {
          "start": 2298906,
          "end": 2300664
        },
        {
          "start": 2303633,
          "end": 2303785
        }
      ],
      "cds": {
        "start": 2061492,
        "end": 2303720
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 1963133,
      "end": 2207065,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 1681814,
      "end": 2681813,
      "genes": [
        {
          "symbol": "PRPF8",
          "ensemblId": "ENSG00000174231",
          "biotype": "protein_coding",
          "start": 1650624,
          "end": 1684909,
          "strand": "-",
          "slug": "prpf8"
        },
        {
          "symbol": "TLCD2",
          "ensemblId": "ENSG00000185561",
          "biotype": "protein_coding",
          "start": 1688598,
          "end": 1710639,
          "strand": "-",
          "slug": "tlcd2"
        },
        {
          "symbol": "WDR81",
          "ensemblId": "ENSG00000167716",
          "biotype": "protein_coding",
          "start": 1716523,
          "end": 1738599,
          "strand": "+",
          "slug": "wdr81"
        },
        {
          "symbol": "SERPINF2",
          "ensemblId": "ENSG00000167711",
          "biotype": "protein_coding",
          "start": 1742069,
          "end": 1755271,
          "strand": "+",
          "slug": "serpinf2"
        },
        {
          "symbol": "SERPINF1",
          "ensemblId": "ENSG00000132386",
          "biotype": "protein_coding",
          "start": 1761958,
          "end": 1777627,
          "strand": "+",
          "slug": "serpinf1"
        },
        {
          "symbol": "SMYD4",
          "ensemblId": "ENSG00000186532",
          "biotype": "protein_coding",
          "start": 1779485,
          "end": 1830634,
          "strand": "-",
          "slug": "smyd4"
        },
        {
          "symbol": "RPA1",
          "ensemblId": "ENSG00000132383",
          "biotype": "protein_coding",
          "start": 1829702,
          "end": 1900082,
          "strand": "+",
          "slug": "rpa1"
        },
        {
          "symbol": "RTN4RL1",
          "ensemblId": "ENSG00000185924",
          "biotype": "protein_coding",
          "start": 1934677,
          "end": 2025355,
          "strand": "-",
          "slug": "rtn4rl1"
        },
        {
          "symbol": "DPH1",
          "ensemblId": "ENSG00000108963",
          "biotype": "protein_coding",
          "start": 2030136,
          "end": 2043898,
          "strand": "+",
          "slug": "dph1"
        },
        {
          "symbol": "OVCA2",
          "ensemblId": "ENSG00000262664",
          "biotype": "protein_coding",
          "start": 2042022,
          "end": 2043898,
          "strand": "+",
          "slug": "ovca2"
        },
        {
          "symbol": "HIC1",
          "ensemblId": "ENSG00000177374",
          "biotype": "protein_coding",
          "start": 2054154,
          "end": 2063241,
          "strand": "+",
          "slug": "hic1"
        },
        {
          "symbol": "SRR",
          "ensemblId": "ENSG00000167720",
          "biotype": "protein_coding",
          "start": 2303383,
          "end": 2326656,
          "strand": "+",
          "slug": "srr"
        },
        {
          "symbol": "TSR1",
          "ensemblId": "ENSG00000167721",
          "biotype": "protein_coding",
          "start": 2322376,
          "end": 2337965,
          "strand": "-",
          "slug": "tsr1"
        },
        {
          "symbol": "SGSM2",
          "ensemblId": "ENSG00000141258",
          "biotype": "protein_coding",
          "start": 2337488,
          "end": 2381058,
          "strand": "+",
          "slug": "sgsm2"
        },
        {
          "symbol": "MNT",
          "ensemblId": "ENSG00000070444",
          "biotype": "protein_coding",
          "start": 2384073,
          "end": 2401142,
          "strand": "-",
          "slug": "mnt"
        },
        {
          "symbol": "METTL16",
          "ensemblId": "ENSG00000127804",
          "biotype": "protein_coding",
          "start": 2405562,
          "end": 2511904,
          "strand": "-",
          "slug": "mettl16"
        },
        {
          "symbol": "PAFAH1B1",
          "ensemblId": "ENSG00000007168",
          "biotype": "protein_coding",
          "start": 2593183,
          "end": 2685627,
          "strand": "+",
          "slug": "pafah1b1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}