{
  "url": "https://dantelabs.com/es/genes/pdia2",
  "gene": {
    "slug": "pdia2",
    "symbol": "PDIA2",
    "name": "protein disulfide isomerase family A member 2",
    "hgnc": "HGNC:14180",
    "summary": null,
    "location": "16p13.3",
    "locusType": "gene with protein product",
    "aliases": [
      "PDA2",
      "PDI",
      "PDIR"
    ],
    "previousSymbols": [
      "PDIP"
    ],
    "ensemblId": "ENSG00000185615",
    "entrezId": 64714,
    "omim": [
      "608012"
    ],
    "uniprot": [
      "Q13087"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "16",
      "start": 283164,
      "end": 287215,
      "strand": "+",
      "ensemblTranscript": "ENST00000219406.11",
      "refseqTranscript": "NM_006849.4",
      "ensemblProtein": "ENSP00000219406.7",
      "refseqProtein": "NP_006840.2",
      "exons": [
        {
          "start": 283164,
          "end": 283368
        },
        {
          "start": 284387,
          "end": 284593
        },
        {
          "start": 284659,
          "end": 284792
        },
        {
          "start": 284878,
          "end": 285015
        },
        {
          "start": 285084,
          "end": 285200
        },
        {
          "start": 285312,
          "end": 285437
        },
        {
          "start": 285506,
          "end": 285703
        },
        {
          "start": 286353,
          "end": 286473
        },
        {
          "start": 286554,
          "end": 286735
        },
        {
          "start": 286835,
          "end": 286945
        },
        {
          "start": 287069,
          "end": 287215
        }
      ],
      "cds": {
        "start": 283170,
        "end": 287113
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "16",
      "start": 333152,
      "end": 337215,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 1,
      "end": 785189,
      "genes": [
        {
          "symbol": "POLR3K",
          "ensemblId": "ENSG00000161980",
          "biotype": "protein_coding",
          "start": 44356,
          "end": 53663,
          "strand": "-",
          "slug": "polr3k"
        },
        {
          "symbol": "SNRNP25",
          "ensemblId": "ENSG00000161981",
          "biotype": "protein_coding",
          "start": 53817,
          "end": 60009,
          "strand": "+",
          "slug": "snrnp25"
        },
        {
          "symbol": "RHBDF1",
          "ensemblId": "ENSG00000007384",
          "biotype": "protein_coding",
          "start": 58058,
          "end": 78176,
          "strand": "-",
          "slug": "rhbdf1"
        },
        {
          "symbol": "MPG",
          "ensemblId": "ENSG00000103152",
          "biotype": "protein_coding",
          "start": 77007,
          "end": 136889,
          "strand": "+",
          "slug": "mpg"
        },
        {
          "symbol": "NPRL3",
          "ensemblId": "ENSG00000103148",
          "biotype": "protein_coding",
          "start": 79387,
          "end": 138720,
          "strand": "-",
          "slug": "nprl3"
        },
        {
          "symbol": "HBZ",
          "ensemblId": "ENSG00000130656",
          "biotype": "protein_coding",
          "start": 142728,
          "end": 154503,
          "strand": "+",
          "slug": "hbz"
        },
        {
          "symbol": "HBM",
          "ensemblId": "ENSG00000206177",
          "biotype": "protein_coding",
          "start": 153892,
          "end": 166770,
          "strand": "+",
          "slug": "hbm"
        },
        {
          "symbol": "HBA2",
          "ensemblId": "ENSG00000188536",
          "biotype": "protein_coding",
          "start": 172021,
          "end": 173910,
          "strand": "+",
          "slug": "hba2"
        },
        {
          "symbol": "HBA1",
          "ensemblId": "ENSG00000206172",
          "biotype": "protein_coding",
          "start": 176660,
          "end": 177527,
          "strand": "+",
          "slug": "hba1"
        },
        {
          "symbol": "HBQ1",
          "ensemblId": "ENSG00000086506",
          "biotype": "protein_coding",
          "start": 180437,
          "end": 181181,
          "strand": "+",
          "slug": "hbq1"
        },
        {
          "symbol": "LUC7L",
          "ensemblId": "ENSG00000007392",
          "biotype": "protein_coding",
          "start": 188943,
          "end": 229485,
          "strand": "-",
          "slug": "luc7l"
        },
        {
          "symbol": "FAM234A",
          "ensemblId": "ENSG00000167930",
          "biotype": "protein_coding",
          "start": 234521,
          "end": 272183,
          "strand": "+",
          "slug": "fam234a"
        },
        {
          "symbol": "RGS11",
          "ensemblId": "ENSG00000076344",
          "biotype": "protein_coding",
          "start": 268301,
          "end": 275980,
          "strand": "-",
          "slug": "rgs11"
        },
        {
          "symbol": "ARHGDIG",
          "ensemblId": "ENSG00000242173",
          "biotype": "protein_coding",
          "start": 280386,
          "end": 283010,
          "strand": "+",
          "slug": "arhgdig"
        },
        {
          "symbol": "AXIN1",
          "ensemblId": "ENSG00000103126",
          "biotype": "protein_coding",
          "start": 287440,
          "end": 352734,
          "strand": "-",
          "slug": "axin1"
        },
        {
          "symbol": "MRPL28",
          "ensemblId": "ENSG00000086504",
          "biotype": "protein_coding",
          "start": 365449,
          "end": 371289,
          "strand": "-",
          "slug": "mrpl28"
        },
        {
          "symbol": "PGAP6",
          "ensemblId": "ENSG00000129925",
          "biotype": "protein_coding",
          "start": 370779,
          "end": 387113,
          "strand": "-",
          "slug": "pgap6"
        },
        {
          "symbol": "NME4",
          "ensemblId": "ENSG00000103202",
          "biotype": "protein_coding",
          "start": 396725,
          "end": 410367,
          "strand": "+",
          "slug": "nme4"
        },
        {
          "symbol": "DECR2",
          "ensemblId": "ENSG00000242612",
          "biotype": "protein_coding",
          "start": 401834,
          "end": 412492,
          "strand": "+",
          "slug": "decr2"
        },
        {
          "symbol": "RAB11FIP3",
          "ensemblId": "ENSG00000090565",
          "biotype": "protein_coding",
          "start": 425593,
          "end": 523012,
          "strand": "+",
          "slug": "rab11fip3"
        },
        {
          "symbol": "CAPN15",
          "ensemblId": "ENSG00000103326",
          "biotype": "protein_coding",
          "start": 527698,
          "end": 554636,
          "strand": "+",
          "slug": "capn15"
        },
        {
          "symbol": "PRR35",
          "ensemblId": "ENSG00000161992",
          "biotype": "protein_coding",
          "start": 559688,
          "end": 565532,
          "strand": "+",
          "slug": "prr35"
        },
        {
          "symbol": "PIGQ",
          "ensemblId": "ENSG00000007541",
          "biotype": "protein_coding",
          "start": 566995,
          "end": 584121,
          "strand": "+",
          "slug": "pigq"
        },
        {
          "symbol": "NHLRC4",
          "ensemblId": "ENSG00000257108",
          "biotype": "protein_coding",
          "start": 567000,
          "end": 569495,
          "strand": "+",
          "slug": "nhlrc4"
        },
        {
          "symbol": "RAB40C",
          "ensemblId": "ENSG00000197562",
          "biotype": "protein_coding",
          "start": 589007,
          "end": 629348,
          "strand": "+",
          "slug": "rab40c"
        },
        {
          "symbol": "WFIKKN1",
          "ensemblId": "ENSG00000127578",
          "biotype": "protein_coding",
          "start": 629239,
          "end": 634117,
          "strand": "+",
          "slug": "wfikkn1"
        },
        {
          "symbol": "METTL26",
          "ensemblId": "ENSG00000130731",
          "biotype": "protein_coding",
          "start": 634412,
          "end": 636378,
          "strand": "-",
          "slug": "mettl26"
        },
        {
          "symbol": "MCRIP2",
          "ensemblId": "ENSG00000172366",
          "biotype": "protein_coding",
          "start": 636817,
          "end": 648475,
          "strand": "+",
          "slug": "mcrip2"
        },
        {
          "symbol": "WDR90",
          "ensemblId": "ENSG00000161996",
          "biotype": "protein_coding",
          "start": 649287,
          "end": 667837,
          "strand": "+",
          "slug": "wdr90"
        },
        {
          "symbol": "RHOT2",
          "ensemblId": "ENSG00000140983",
          "biotype": "protein_coding",
          "start": 668081,
          "end": 674174,
          "strand": "+",
          "slug": "rhot2"
        },
        {
          "symbol": "RHBDL1",
          "ensemblId": "ENSG00000103269",
          "biotype": "protein_coding",
          "start": 675605,
          "end": 678275,
          "strand": "+",
          "slug": "rhbdl1"
        },
        {
          "symbol": "STUB1",
          "ensemblId": "ENSG00000103266",
          "biotype": "protein_coding",
          "start": 679980,
          "end": 682870,
          "strand": "+",
          "slug": "stub1"
        },
        {
          "symbol": "JMJD8",
          "ensemblId": "ENSG00000161999",
          "biotype": "protein_coding",
          "start": 681666,
          "end": 684528,
          "strand": "-",
          "slug": "jmjd8"
        },
        {
          "symbol": "WDR24",
          "ensemblId": "ENSG00000127580",
          "biotype": "protein_coding",
          "start": 684614,
          "end": 690444,
          "strand": "-",
          "slug": "wdr24"
        },
        {
          "symbol": "FBXL16",
          "ensemblId": "ENSG00000127585",
          "biotype": "protein_coding",
          "start": 692498,
          "end": 705860,
          "strand": "-",
          "slug": "fbxl16"
        },
        {
          "symbol": "METRN",
          "ensemblId": "ENSG00000103260",
          "biotype": "protein_coding",
          "start": 715093,
          "end": 719796,
          "strand": "+",
          "slug": "metrn"
        },
        {
          "symbol": "ANTKMT",
          "ensemblId": "ENSG00000103254",
          "biotype": "protein_coding",
          "start": 720581,
          "end": 722590,
          "strand": "+",
          "slug": "antkmt"
        },
        {
          "symbol": "CCDC78",
          "ensemblId": "ENSG00000162004",
          "biotype": "protein_coding",
          "start": 722581,
          "end": 726954,
          "strand": "-",
          "slug": "ccdc78"
        },
        {
          "symbol": "HAGHL",
          "ensemblId": "ENSG00000103253",
          "biotype": "protein_coding",
          "start": 726494,
          "end": 735525,
          "strand": "+",
          "slug": "haghl"
        },
        {
          "symbol": "CIAO3",
          "ensemblId": "ENSG00000103245",
          "biotype": "protein_coding",
          "start": 729721,
          "end": 741329,
          "strand": "-",
          "slug": "ciao3"
        },
        {
          "symbol": "MSLN",
          "ensemblId": "ENSG00000102854",
          "biotype": "protein_coding",
          "start": 760729,
          "end": 768866,
          "strand": "+",
          "slug": "msln"
        },
        {
          "symbol": "MSLNL",
          "ensemblId": "ENSG00000162006",
          "biotype": "protein_coding",
          "start": 769428,
          "end": 782054,
          "strand": "-",
          "slug": "mslnl"
        },
        {
          "symbol": "RPUSD1",
          "ensemblId": "ENSG00000007376",
          "biotype": "protein_coding",
          "start": 784974,
          "end": 788406,
          "strand": "-",
          "slug": "rpusd1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}