{
  "url": "https://dantelabs.com/es/genes/lmo1",
  "gene": {
    "slug": "lmo1",
    "symbol": "LMO1",
    "name": "LIM domain only 1",
    "hgnc": "HGNC:6641",
    "summary": null,
    "location": "11p15.4",
    "locusType": "gene with protein product",
    "aliases": [
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      "RHOM1"
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    "previousSymbols": [
      "RBTN1"
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    "ensemblId": "ENSG00000166407",
    "entrezId": 4004,
    "omim": [
      "186921"
    ],
    "uniprot": [
      "P25800"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "11",
      "start": 8224309,
      "end": 8263878,
      "strand": "-",
      "ensemblTranscript": "ENST00000335790.8",
      "refseqTranscript": "NM_002315.3",
      "ensemblProtein": "ENSP00000338207.3",
      "refseqProtein": "NP_002306.1",
      "exons": [
        {
          "start": 8224309,
          "end": 8224721
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        {
          "start": 8226975,
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        },
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      ],
      "cds": {
        "start": 8224616,
        "end": 8263362
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "11",
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      "end": 8290263,
      "strand": "-"
    },
    "neighbourhood": {
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      "genes": [
        {
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          "ensemblId": "ENSG00000183303",
          "biotype": "protein_coding",
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          "end": 7796942,
          "strand": "-",
          "slug": "or5p2"
        },
        {
          "symbol": "OR5P3",
          "ensemblId": "ENSG00000182334",
          "biotype": "protein_coding",
          "start": 7824818,
          "end": 7830840,
          "strand": "-",
          "slug": "or5p3"
        },
        {
          "symbol": "OR10A6",
          "ensemblId": "ENSG00000279000",
          "biotype": "protein_coding",
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          "strand": "-",
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        },
        {
          "symbol": "OR10A3",
          "ensemblId": "ENSG00000170683",
          "biotype": "protein_coding",
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          "end": 7941708,
          "strand": "-",
          "slug": "or10a3"
        },
        {
          "symbol": "NLRP10",
          "ensemblId": "ENSG00000182261",
          "biotype": "protein_coding",
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          "end": 7965447,
          "strand": "-",
          "slug": "nlrp10"
        },
        {
          "symbol": "EIF3F",
          "ensemblId": "ENSG00000175390",
          "biotype": "protein_coding",
          "start": 7970251,
          "end": 8001862,
          "strand": "+",
          "slug": "eif3f"
        },
        {
          "symbol": "TUB",
          "ensemblId": "ENSG00000166402",
          "biotype": "protein_coding",
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          "end": 8106243,
          "strand": "+",
          "slug": "tub"
        },
        {
          "symbol": "RIC3",
          "ensemblId": "ENSG00000166405",
          "biotype": "protein_coding",
          "start": 8092965,
          "end": 8169096,
          "strand": "-",
          "slug": "ric3"
        },
        {
          "symbol": "STK33",
          "ensemblId": "ENSG00000130413",
          "biotype": "protein_coding",
          "start": 8391864,
          "end": 8594292,
          "strand": "-",
          "slug": "stk33"
        },
        {
          "symbol": "TRIM66",
          "ensemblId": "ENSG00000166436",
          "biotype": "protein_coding",
          "start": 8612037,
          "end": 8682694,
          "strand": "-",
          "slug": "trim66"
        },
        {
          "symbol": "RPL27A",
          "ensemblId": "ENSG00000166441",
          "biotype": "protein_coding",
          "start": 8682732,
          "end": 8714759,
          "strand": "+",
          "slug": "rpl27a"
        },
        {
          "symbol": "DENND2B",
          "ensemblId": "ENSG00000166444",
          "biotype": "protein_coding",
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          "end": 8910951,
          "strand": "-",
          "slug": "dennd2b"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abdominal-distention",
        "name": "Abdominal bloating",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abdominal-distention"
      },
      {
        "slug": "abdominal-mass",
        "name": "Abdominal mass",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abdominal-mass"
      },
      {
        "slug": "abnormality-of-coagulation",
        "name": "Abnormality of coagulation",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-coagulation"
      },
      {
        "slug": "anemic-pallor",
        "name": "Anemic pallor",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/anemic-pallor"
      },
      {
        "slug": "antalgic-gait",
        "name": "Antalgic gait",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/antalgic-gait"
      },
      {
        "slug": "ataxia",
        "name": "Ataxia",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/ataxia"
      },
      {
        "slug": "abnormal-bleeding",
        "name": "Bleeding tendency",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-bleeding"
      },
      {
        "slug": "bone-pain",
        "name": "Bone pain",
        "systems": [
          "abnormality-of-the-musculoskeletal-system",
          "constitutional-symptom"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/bone-pain"
      },
      {
        "slug": "respiratory-distress",
        "name": "Breathing difficulties",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/respiratory-distress"
      },
      {
        "slug": "proptosis",
        "name": "Bulging eye",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/proptosis"
      },
      {
        "slug": "neuroblastoma",
        "name": "Cancer of early nerve cells",
        "systems": [
          "abnormality-of-the-nervous-system",
          "neoplasm"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/neuroblastoma"
      },
      {
        "slug": "chronic-diarrhea",
        "name": "Chronic diarrhea",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chronic-diarrhea"
      },
      {
        "slug": "elevated-circulating-catecholamine-level",
        "name": "Elevated circulating catecholamine level",
        "systems": [
          "abnormality-of-the-endocrine-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/elevated-circulating-catecholamine-level"
      },
      {
        "slug": "increased-circulating-ferritin-concentration",
        "name": "Elevated serum ferritin",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/increased-circulating-ferritin-concentration"
      },
      {
        "slug": "elevated-urinary-catecholamine-level",
        "name": "Elevated urinary catecholamines",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/elevated-urinary-catecholamine-level"
      },
      {
        "slug": "elevated-urinary-homovanillic-acid",
        "name": "Elevated urinary homovanillic acid",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/elevated-urinary-homovanillic-acid"
      },
      {
        "slug": "elevated-urinary-vanillylmandelic-acid",
        "name": "Elevated urinary vanillylmandelic acid",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/elevated-urinary-vanillylmandelic-acid"
      },
      {
        "slug": "fatigue",
        "name": "Fatigue",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatigue"
      },
      {
        "slug": "fever",
        "name": "Fever",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fever"
      },
      {
        "slug": "subcutaneous-nodule",
        "name": "Firm lump under the skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/subcutaneous-nodule"
      },
      {
        "slug": "hypertension",
        "name": "High blood pressure",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hypertension"
      },
      {
        "slug": "horner-syndrome",
        "name": "Horner syndrome",
        "systems": [
          "abnormality-of-the-eye",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/horner-syndrome"
      },
      {
        "slug": "increased-circulating-lactate-dehydrogenase-concentration",
        "name": "Increased circulating lactate dehydrogenase concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/increased-circulating-lactate-dehydrogenase-concentration"
      },
      {
        "slug": "irritability",
        "name": "Irritability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/irritability"
      },
      {
        "slug": "myoclonus",
        "name": "Jerking",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/myoclonus"
      },
      {
        "slug": "anemia",
        "name": "Low number of red blood cells or hemoglobin",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/anemia"
      },
      {
        "slug": "thrombocytopenia",
        "name": "Low platelet count",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/thrombocytopenia"
      },
      {
        "slug": "neoplasm-of-the-nervous-system",
        "name": "Nervous system cancer",
        "systems": [
          "abnormality-of-the-nervous-system",
          "neoplasm"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-nervous-system"
      },
      {
        "slug": "opsoclonus",
        "name": "Opsoclonus",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/opsoclonus"
      },
      {
        "slug": "spinal-cord-compression",
        "name": "Pressure on spinal cord",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/spinal-cord-compression"
      },
      {
        "slug": "periorbital-ecchymosis-with-tarsal-plate-sparing",
        "name": "Raccoon eyes",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/periorbital-ecchymosis-with-tarsal-plate-sparing"
      },
      {
        "slug": "pathologic-fracture",
        "name": "Spontaneous fracture",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pathologic-fracture"
      },
      {
        "slug": "lymphadenopathy",
        "name": "Swollen lymph nodes",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/lymphadenopathy"
      },
      {
        "slug": "weight-loss",
        "name": "Weight loss",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/weight-loss"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}