{
  "url": "https://dantelabs.com/es/genes/kcna5",
  "gene": {
    "slug": "kcna5",
    "symbol": "KCNA5",
    "name": "potassium voltage-gated channel subfamily A member 5",
    "hgnc": "HGNC:6224",
    "summary": null,
    "location": "12p13.32",
    "locusType": "gene with protein product",
    "aliases": [
      "Kv1.5",
      "HK2",
      "HPCN1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000130037",
    "entrezId": 3741,
    "omim": [
      "176267"
    ],
    "uniprot": [
      "P22460"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "12",
      "start": 5043879,
      "end": 5046788,
      "strand": "+",
      "ensemblTranscript": "ENST00000252321.5",
      "refseqTranscript": "NM_002234.4",
      "ensemblProtein": "ENSP00000252321.3",
      "refseqProtein": "NP_002225.2",
      "exons": [
        {
          "start": 5043879,
          "end": 5046788
        }
      ],
      "cds": {
        "start": 5044148,
        "end": 5045989
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "12",
      "start": 5153085,
      "end": 5155949,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 4545334,
      "end": 5545333,
      "genes": [
        {
          "symbol": "RAD51AP1",
          "ensemblId": "ENSG00000111247",
          "biotype": "protein_coding",
          "start": 4538775,
          "end": 4560254,
          "strand": "+",
          "slug": "rad51ap1"
        },
        {
          "symbol": "DYRK4",
          "ensemblId": "ENSG00000010219",
          "biotype": "protein_coding",
          "start": 4562187,
          "end": 4616764,
          "strand": "+",
          "slug": "dyrk4"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000272921",
          "biotype": "protein_coding",
          "start": 4604944,
          "end": 4662643,
          "strand": "+"
        },
        {
          "symbol": "AKAP3",
          "ensemblId": "ENSG00000111254",
          "biotype": "protein_coding",
          "start": 4613383,
          "end": 4649072,
          "strand": "-",
          "slug": "akap3"
        },
        {
          "symbol": "NDUFA9",
          "ensemblId": "ENSG00000139180",
          "biotype": "protein_coding",
          "start": 4649095,
          "end": 4701398,
          "strand": "+",
          "slug": "ndufa9"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000255639",
          "biotype": "protein_coding",
          "start": 4649101,
          "end": 4774184,
          "strand": "+"
        },
        {
          "symbol": "GALNT8",
          "ensemblId": "ENSG00000130035",
          "biotype": "protein_coding",
          "start": 4719870,
          "end": 4851927,
          "strand": "+",
          "slug": "galnt8"
        },
        {
          "symbol": "KCNA6",
          "ensemblId": "ENSG00000151079",
          "biotype": "protein_coding",
          "start": 4809334,
          "end": 4813318,
          "strand": "+",
          "slug": "kcna6"
        },
        {
          "symbol": "KCNA1",
          "ensemblId": "ENSG00000111262",
          "biotype": "protein_coding",
          "start": 4909905,
          "end": 4918256,
          "strand": "+",
          "slug": "kcna1"
        },
        {
          "symbol": "NTF3",
          "ensemblId": "ENSG00000185652",
          "biotype": "protein_coding",
          "start": 5432088,
          "end": 5521536,
          "strand": "+",
          "slug": "ntf3"
        },
        {
          "symbol": "ANO2",
          "ensemblId": "ENSG00000047617",
          "biotype": "protein_coding",
          "start": 5531869,
          "end": 5946232,
          "strand": "-",
          "slug": "ano2"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "dyspnea",
        "name": "Breathing difficulty",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/dyspnea"
      },
      {
        "slug": "chest-pain",
        "name": "Chest pain",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/chest-pain"
      },
      {
        "slug": "exercise-intolerance",
        "name": "Decreased ability to exercise",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/exercise-intolerance"
      },
      {
        "slug": "vertigo",
        "name": "Dizziness",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/vertigo"
      },
      {
        "slug": "syncope",
        "name": "Fainting spell",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/syncope"
      },
      {
        "slug": "fatigue",
        "name": "Fatigue",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatigue"
      },
      {
        "slug": "myocardial-infarction",
        "name": "Heart attack",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/myocardial-infarction"
      },
      {
        "slug": "palpitations",
        "name": "Palpitations",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/palpitations"
      },
      {
        "slug": "paroxysmal-atrial-fibrillation",
        "name": "Paroxysmal atrial fibrillation",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/paroxysmal-atrial-fibrillation"
      },
      {
        "slug": "permanent-atrial-fibrillation",
        "name": "Permanent atrial fibrillation",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/permanent-atrial-fibrillation"
      },
      {
        "slug": "premature-atrial-contractions",
        "name": "Premature atrial contractions",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/premature-atrial-contractions"
      },
      {
        "slug": "prolonged-pr-interval",
        "name": "Prolonged PR interval",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/prolonged-pr-interval"
      },
      {
        "slug": "prolonged-qtc-interval",
        "name": "Prolonged QTc interval",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/prolonged-qtc-interval"
      },
      {
        "slug": "atrial-fibrillation",
        "name": "Quivering upper heart chambers resulting in irregular heartbeat",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/atrial-fibrillation"
      },
      {
        "slug": "sinus-bradycardia",
        "name": "Sinus bradycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/sinus-bradycardia"
      },
      {
        "slug": "thromboembolic-stroke",
        "name": "Thromboembolic stroke",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/thromboembolic-stroke"
      },
      {
        "slug": "thromboembolism",
        "name": "Thromboembolism",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/thromboembolism"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}