{
  "url": "https://dantelabs.com/es/genes/apaf1",
  "gene": {
    "slug": "apaf1",
    "symbol": "APAF1",
    "name": "apoptotic peptidase activating factor 1",
    "hgnc": "HGNC:576",
    "summary": null,
    "location": "12q23.1",
    "locusType": "gene with protein product",
    "aliases": [
      "CED4",
      "APAF-1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000120868",
    "entrezId": 317,
    "omim": [
      "602233"
    ],
    "uniprot": [
      "O14727"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "12",
      "start": 98645290,
      "end": 98735433,
      "strand": "+",
      "ensemblTranscript": "ENST00000551964.6",
      "refseqTranscript": "NM_181861.2",
      "ensemblProtein": "ENSP00000448165.2",
      "refseqProtein": "NP_863651.1",
      "exons": [
        {
          "start": 98645290,
          "end": 98645835
        },
        {
          "start": 98648319,
          "end": 98648497
        },
        {
          "start": 98648626,
          "end": 98648815
        },
        {
          "start": 98649487,
          "end": 98649684
        },
        {
          "start": 98659160,
          "end": 98659343
        },
        {
          "start": 98662456,
          "end": 98662568
        },
        {
          "start": 98662675,
          "end": 98662806
        },
        {
          "start": 98665553,
          "end": 98665791
        },
        {
          "start": 98666190,
          "end": 98666357
        },
        {
          "start": 98667513,
          "end": 98667644
        },
        {
          "start": 98670973,
          "end": 98671086
        },
        {
          "start": 98671535,
          "end": 98671719
        },
        {
          "start": 98677425,
          "end": 98677551
        },
        {
          "start": 98680277,
          "end": 98680402
        },
        {
          "start": 98683143,
          "end": 98683274
        },
        {
          "start": 98686748,
          "end": 98686873
        },
        {
          "start": 98699408,
          "end": 98699569
        },
        {
          "start": 98703371,
          "end": 98703499
        },
        {
          "start": 98706485,
          "end": 98706610
        },
        {
          "start": 98708585,
          "end": 98708704
        },
        {
          "start": 98712319,
          "end": 98712435
        },
        {
          "start": 98715427,
          "end": 98715552
        },
        {
          "start": 98723193,
          "end": 98723312
        },
        {
          "start": 98723639,
          "end": 98723764
        },
        {
          "start": 98725415,
          "end": 98725540
        },
        {
          "start": 98727173,
          "end": 98727316
        },
        {
          "start": 98732420,
          "end": 98735433
        }
      ],
      "cds": {
        "start": 98648360,
        "end": 98732566
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "12",
      "start": 99038919,
      "end": 99129204,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 98190362,
      "end": 99190361,
      "genes": [
        {
          "symbol": "TMPO",
          "ensemblId": "ENSG00000120802",
          "biotype": "protein_coding",
          "start": 98515483,
          "end": 98550351,
          "strand": "+",
          "slug": "tmpo"
        },
        {
          "symbol": "SLC25A3",
          "ensemblId": "ENSG00000075415",
          "biotype": "protein_coding",
          "start": 98574411,
          "end": 98606379,
          "strand": "+",
          "slug": "slc25a3"
        },
        {
          "symbol": "IKBIP",
          "ensemblId": "ENSG00000166130",
          "biotype": "protein_coding",
          "start": 98613405,
          "end": 98645113,
          "strand": "-",
          "slug": "ikbip"
        },
        {
          "symbol": "ANKS1B",
          "ensemblId": "ENSG00000185046",
          "biotype": "protein_coding",
          "start": 98726457,
          "end": 99984964,
          "strand": "-",
          "slug": "anks1b"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}