{
  "url": "https://dantelabs.com/traits/ruffled-acrosome",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "ruffled-acrosome",
    "id": "HP:6000501",
    "name": "Ruffled acrosome",
    "definition": "An irregular wavy appearance of sperm acrosomes.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-sperm-head-morphology",
        "name": "Abnormal sperm head morphology",
        "url": "https://dantelabs.com/traits/abnormal-sperm-head-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "acr",
        "symbol": "ACR",
        "hgnc": "HGNC:126",
        "name": "acrosin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/acr"
      },
      {
        "slug": "actl7a",
        "symbol": "ACTL7A",
        "hgnc": "HGNC:161",
        "name": "actin like 7A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actl7a"
      }
    ]
  }
}