{
  "url": "https://dantelabs.com/traits/pineal-cyst",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "pineal-cyst",
    "id": "HP:0012683",
    "name": "Pineal cyst",
    "definition": "A glial uniloculated or multiloculated fluid-filled sac that either reside within or completely replace the pineal gland.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-pineal-morphology",
        "name": "Abnormal pineal morphology",
        "url": "https://dantelabs.com/traits/abnormal-pineal-morphology"
      },
      {
        "slug": "intracranial-cystic-lesion",
        "name": "Intracranial cystic lesion",
        "url": "https://dantelabs.com/traits/intracranial-cystic-lesion"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "man2b2",
        "symbol": "MAN2B2",
        "hgnc": "HGNC:29623",
        "name": "mannosidase alpha class 2B member 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2b2"
      },
      {
        "slug": "nono",
        "symbol": "NONO",
        "hgnc": "HGNC:7871",
        "name": "non-POU domain containing octamer binding",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nono"
      },
      {
        "slug": "tm2d3",
        "symbol": "TM2D3",
        "hgnc": "HGNC:24128",
        "name": "TM2 domain containing 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tm2d3"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kras"
      },
      {
        "slug": "psmd12",
        "symbol": "PSMD12",
        "hgnc": "HGNC:9557",
        "name": "proteasome 26S subunit, non-ATPase 12",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/psmd12"
      },
      {
        "slug": "adnp",
        "symbol": "ADNP",
        "hgnc": "HGNC:15766",
        "name": "activity dependent neuroprotector homeobox",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adnp"
      },
      {
        "slug": "galnt2",
        "symbol": "GALNT2",
        "hgnc": "HGNC:4124",
        "name": "polypeptide N-acetylgalactosaminyltransferase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galnt2"
      },
      {
        "slug": "wdr26",
        "symbol": "WDR26",
        "hgnc": "HGNC:21208",
        "name": "WD repeat domain 26",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wdr26"
      },
      {
        "slug": "bptf",
        "symbol": "BPTF",
        "hgnc": "HGNC:3581",
        "name": "bromodomain PHD finger transcription factor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bptf"
      },
      {
        "slug": "pnpla2",
        "symbol": "PNPLA2",
        "hgnc": "HGNC:30802",
        "name": "patatin like domain 2, triacylglycerol lipase",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnpla2"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "hgnc": "HGNC:10193",
        "name": "RNA, U4 small nuclear 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4-2"
      }
    ]
  }
}