{
  "url": "https://dantelabs.com/traits/nevus-spilus",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "nevus-spilus",
    "id": "HP:0025510",
    "name": "Nevus spilus",
    "definition": "A tan, regularly bordered patch with darker macules within the lesion.",
    "synonyms": [
      "Speckled lentiginous Nevus"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "nevus",
        "name": "Mole",
        "url": "https://dantelabs.com/traits/nevus"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "hras",
        "symbol": "HRAS",
        "hgnc": "HGNC:5173",
        "name": "HRas proto-oncogene, GTPase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hras"
      },
      {
        "slug": "pigh",
        "symbol": "PIGH",
        "hgnc": "HGNC:8964",
        "name": "phosphatidylinositol glycan anchor biosynthesis class H",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigh"
      },
      {
        "slug": "nras",
        "symbol": "NRAS",
        "hgnc": "HGNC:7989",
        "name": "NRAS proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nras"
      }
    ]
  }
}