{
  "url": "https://dantelabs.com/traits/irregular-dentition",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "irregular-dentition",
    "id": "HP:0040079",
    "name": "Irregular teeth",
    "label": "Irregular dentition",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-dental-morphology",
        "name": "Abnormality of dental shape",
        "url": "https://dantelabs.com/traits/abnormal-dental-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "fat4",
        "symbol": "FAT4",
        "hgnc": "HGNC:23109",
        "name": "FAT atypical cadherin 4",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/fat4"
      },
      {
        "slug": "rin2",
        "symbol": "RIN2",
        "hgnc": "HGNC:18750",
        "name": "Ras and Rab interactor 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rin2"
      },
      {
        "slug": "nfix",
        "symbol": "NFIX",
        "hgnc": "HGNC:7788",
        "name": "nuclear factor I X",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nfix"
      },
      {
        "slug": "nmnat1",
        "symbol": "NMNAT1",
        "hgnc": "HGNC:17877",
        "name": "nicotinamide nucleotide adenylyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nmnat1"
      },
      {
        "slug": "dchs1",
        "symbol": "DCHS1",
        "hgnc": "HGNC:13681",
        "name": "dachsous cadherin-related 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dchs1"
      },
      {
        "slug": "sox9",
        "symbol": "SOX9",
        "hgnc": "HGNC:11204",
        "name": "SRY-box transcription factor 9",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox9"
      }
    ]
  }
}