{
  "url": "https://dantelabs.com/traits/insulinoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "insulinoma",
    "id": "HP:0012197",
    "name": "Insulinoma",
    "definition": "A type of tumor of the pancreatic beta cells that secretes excess insulin and can result in hypoglycemia.",
    "synonyms": [
      "Pancreatic insulinoma"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "pancreatic-islet-cell-adenoma",
        "name": "Pancreatic islet cell adenoma",
        "url": "https://dantelabs.com/traits/pancreatic-islet-cell-adenoma"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cdkn1b",
        "symbol": "CDKN1B",
        "hgnc": "HGNC:1785",
        "name": "cyclin dependent kinase inhibitor 1B",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdkn1b"
      },
      {
        "slug": "mafa",
        "symbol": "MAFA",
        "hgnc": "HGNC:23145",
        "name": "MAF bZIP transcription factor A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mafa"
      },
      {
        "slug": "cdkn2b",
        "symbol": "CDKN2B",
        "hgnc": "HGNC:1788",
        "name": "cyclin dependent kinase inhibitor 2B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdkn2b"
      },
      {
        "slug": "men1",
        "symbol": "MEN1",
        "hgnc": "HGNC:7010",
        "name": "menin 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/men1"
      }
    ]
  }
}