{
  "url": "https://dantelabs.com/traits/hypocalciuria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hypocalciuria",
    "id": "HP:0003127",
    "name": "Low urine calcium levels",
    "label": "Hypocalciuria",
    "definition": "An abnormally decreased calcium concentration in the urine.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-urine-calcium-concentration",
        "name": "Abnormality of urine calcium concentration",
        "url": "https://dantelabs.com/traits/abnormality-of-urine-calcium-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "casr",
        "symbol": "CASR",
        "hgnc": "HGNC:1514",
        "name": "calcium sensing receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/casr"
      },
      {
        "slug": "cyp27b1",
        "symbol": "CYP27B1",
        "hgnc": "HGNC:2606",
        "name": "cytochrome P450 family 27 subfamily B member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp27b1"
      },
      {
        "slug": "phex",
        "symbol": "PHEX",
        "hgnc": "HGNC:8918",
        "name": "phosphate regulating endopeptidase X-linked",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phex"
      },
      {
        "slug": "clcnkb",
        "symbol": "CLCNKB",
        "hgnc": "HGNC:2027",
        "name": "chloride voltage-gated channel Kb",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcnkb"
      },
      {
        "slug": "fam20a",
        "symbol": "FAM20A",
        "hgnc": "HGNC:23015",
        "name": "FAM20A golgi associated secretory pathway pseudokinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam20a"
      },
      {
        "slug": "fxyd2",
        "symbol": "FXYD2",
        "hgnc": "HGNC:4026",
        "name": "FXYD domain containing ion transport regulator 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fxyd2"
      },
      {
        "slug": "ap2s1",
        "symbol": "AP2S1",
        "hgnc": "HGNC:565",
        "name": "adaptor related protein complex 2 subunit sigma 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ap2s1"
      },
      {
        "slug": "cldn10",
        "symbol": "CLDN10",
        "hgnc": "HGNC:2033",
        "name": "claudin 10",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn10"
      },
      {
        "slug": "gna11",
        "symbol": "GNA11",
        "hgnc": "HGNC:4379",
        "name": "G protein subunit alpha 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gna11"
      },
      {
        "slug": "kcnj10",
        "symbol": "KCNJ10",
        "hgnc": "HGNC:6256",
        "name": "potassium inwardly rectifying channel subfamily J member 10",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj10"
      },
      {
        "slug": "slc12a3",
        "symbol": "SLC12A3",
        "hgnc": "HGNC:10912",
        "name": "solute carrier family 12 member 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a3"
      }
    ]
  }
}