{
  "url": "https://dantelabs.com/traits/distichiasis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "distichiasis",
    "id": "HP:0009743",
    "name": "Distichiasis",
    "definition": "Double rows of eyelashes.",
    "synonyms": [
      "Distichiasis of eyelid eyelashes"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "multiple-rows-of-eyelashes",
        "name": "Multiple rows of eyelashes",
        "url": "https://dantelabs.com/traits/multiple-rows-of-eyelashes"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cdh1",
        "symbol": "CDH1",
        "hgnc": "HGNC:1748",
        "name": "cadherin 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdh1"
      },
      {
        "slug": "foxc2",
        "symbol": "FOXC2",
        "hgnc": "HGNC:3801",
        "name": "forkhead box C2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/foxc2"
      },
      {
        "slug": "ctnnd1",
        "symbol": "CTNND1",
        "hgnc": "HGNC:2515",
        "name": "catenin delta 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ctnnd1"
      },
      {
        "slug": "pus1",
        "symbol": "PUS1",
        "hgnc": "HGNC:15508",
        "name": "pseudouridine synthase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pus1"
      },
      {
        "slug": "twist2",
        "symbol": "TWIST2",
        "hgnc": "HGNC:20670",
        "name": "twist family bHLH transcription factor 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/twist2"
      },
      {
        "slug": "yars2",
        "symbol": "YARS2",
        "hgnc": "HGNC:24249",
        "name": "tyrosyl-tRNA synthetase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/yars2"
      },
      {
        "slug": "prr12",
        "symbol": "PRR12",
        "hgnc": "HGNC:29217",
        "name": "proline rich 12",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prr12"
      },
      {
        "slug": "hspg2",
        "symbol": "HSPG2",
        "hgnc": "HGNC:5273",
        "name": "heparan sulfate proteoglycan 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hspg2"
      }
    ]
  }
}