{
  "url": "https://dantelabs.com/traits/absent-gallbladder",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "absent-gallbladder",
    "id": "HP:0011467",
    "name": "Absent gallbladder",
    "definition": "A developmental defect in which the gallbladder fails to form.",
    "synonyms": [
      "Agenesis of the gallbladder",
      "Aplasia of the gallbladder"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "aplasia-hypoplasia-of-the-gallbladder",
        "name": "Absent/small gallbladder",
        "url": "https://dantelabs.com/traits/aplasia-hypoplasia-of-the-gallbladder"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "rfx6",
        "symbol": "RFX6",
        "hgnc": "HGNC:21478",
        "name": "regulatory factor X6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfx6"
      },
      {
        "slug": "cnot1",
        "symbol": "CNOT1",
        "hgnc": "HGNC:7877",
        "name": "CCR4-NOT transcription complex subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnot1"
      },
      {
        "slug": "cc2d2a",
        "symbol": "CC2D2A",
        "hgnc": "HGNC:29253",
        "name": "coiled-coil and C2 domain containing 2A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cc2d2a"
      },
      {
        "slug": "foxf1",
        "symbol": "FOXF1",
        "hgnc": "HGNC:3809",
        "name": "forkhead box F1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxf1"
      },
      {
        "slug": "gata6",
        "symbol": "GATA6",
        "hgnc": "HGNC:4174",
        "name": "GATA binding protein 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gata6"
      },
      {
        "slug": "son",
        "symbol": "SON",
        "hgnc": "HGNC:11183",
        "name": "SON DNA and RNA binding protein",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/son"
      },
      {
        "slug": "intu",
        "symbol": "INTU",
        "hgnc": "HGNC:29239",
        "name": "inturned planar cell polarity protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/intu"
      }
    ]
  }
}