{
  "url": "https://dantelabs.com/traits/abnormal-lymphocyte-count",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "abnormal-lymphocyte-count",
    "id": "HP:0040088",
    "name": "Abnormal lymphocyte count",
    "definition": "Any abnormality in the total number of lymphocytes in the blood.",
    "synonyms": [
      "Abnormal lymphocyte counts",
      "Abnormal number of lymphocytes",
      "Abnormal numbers of lymphocytes",
      "Abnormality of lymphocyte number"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-lymphocyte-morphology",
        "name": "Abnormal lymphocyte morphology",
        "url": "https://dantelabs.com/traits/abnormal-lymphocyte-morphology"
      },
      {
        "slug": "abnormal-leukocyte-count",
        "name": "Abnormal white blood cell count",
        "url": "https://dantelabs.com/traits/abnormal-leukocyte-count"
      }
    ],
    "narrower": [
      {
        "slug": "decreased-total-lymphocyte-count",
        "name": "Decreased blood lymphocyte number",
        "genes": 129,
        "url": "https://dantelabs.com/traits/decreased-total-lymphocyte-count"
      },
      {
        "slug": "increased-total-lymphocyte-count",
        "name": "High lymphocyte count",
        "genes": 19,
        "url": "https://dantelabs.com/traits/increased-total-lymphocyte-count"
      },
      {
        "slug": "abnormal-total-b-cell-count",
        "name": "Abnormal total B cell count",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-total-b-cell-count"
      },
      {
        "slug": "abnormal-total-t-cell-number",
        "name": "Abnormal total T cell number",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormal-total-t-cell-number"
      }
    ],
    "genes": [
      {
        "slug": "cd3e",
        "symbol": "CD3E",
        "hgnc": "HGNC:1674",
        "name": "CD3 epsilon subunit of T-cell receptor complex",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd3e"
      },
      {
        "slug": "sp110",
        "symbol": "SP110",
        "hgnc": "HGNC:5401",
        "name": "SP110 nuclear body protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sp110"
      }
    ]
  }
}