{
  "url": "https://dantelabs.com/traits/abnormal-eye-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-eye-morphology",
    "id": "HP:0012372",
    "name": "Abnormal eye structure",
    "label": "Abnormal eye morphology",
    "definition": "A structural anomaly of the globe of the eye, or bulbus oculi.",
    "synonyms": [
      "Abnormally shaped eye",
      "Abnormality of the globe"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "narrower": [
      {
        "slug": "coloboma",
        "name": "Notched pupil",
        "genes": 73,
        "url": "https://dantelabs.com/traits/coloboma"
      },
      {
        "slug": "phthisis-bulbi",
        "name": "Phthisis bulbi",
        "genes": 19,
        "url": "https://dantelabs.com/traits/phthisis-bulbi"
      },
      {
        "slug": "neoplasm-of-the-eye",
        "name": "Eye tumor",
        "genes": 8,
        "url": "https://dantelabs.com/traits/neoplasm-of-the-eye"
      },
      {
        "slug": "aplasia-hypoplasia-affecting-the-eye",
        "name": "Absent/small eye",
        "genes": 4,
        "url": "https://dantelabs.com/traits/aplasia-hypoplasia-affecting-the-eye"
      },
      {
        "slug": "abnormality-of-globe-location",
        "name": "Abnormality of eyeball location",
        "genes": 2,
        "url": "https://dantelabs.com/traits/abnormality-of-globe-location"
      },
      {
        "slug": "abnormal-anterior-eye-segment-morphology",
        "name": "Abnormal anterior eye segment morphology",
        "genes": 1,
        "url": "https://dantelabs.com/traits/abnormal-anterior-eye-segment-morphology"
      },
      {
        "slug": "abnormality-of-globe-size",
        "name": "Abnormality of eyeball size",
        "genes": 1,
        "url": "https://dantelabs.com/traits/abnormality-of-globe-size"
      },
      {
        "slug": "abnormal-sclera-morphology",
        "name": "Abnormality of the outer white part of eyeball",
        "genes": 1,
        "url": "https://dantelabs.com/traits/abnormal-sclera-morphology"
      },
      {
        "slug": "abnormal-posterior-eye-segment-morphology",
        "name": "Abnormal posterior eye segment morphology",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-posterior-eye-segment-morphology"
      },
      {
        "slug": "abnormal-uvea-morphology",
        "name": "Abnormal uvea morphology",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-uvea-morphology"
      },
      {
        "slug": "abnormality-of-the-vasculature-of-the-eye",
        "name": "Abnormality of eye blood vessels",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormality-of-the-vasculature-of-the-eye"
      }
    ],
    "genes": [
      {
        "slug": "fkbp14",
        "symbol": "FKBP14",
        "hgnc": "HGNC:18625",
        "name": "FKBP prolyl isomerase 14",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fkbp14"
      },
      {
        "slug": "zeb2",
        "symbol": "ZEB2",
        "hgnc": "HGNC:14881",
        "name": "zinc finger E-box binding homeobox 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zeb2"
      },
      {
        "slug": "tshr",
        "symbol": "TSHR",
        "hgnc": "HGNC:12373",
        "name": "thyroid stimulating hormone receptor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tshr"
      }
    ]
  }
}