{
  "url": "https://dantelabs.com/el/genes/rmp64",
  "gene": {
    "slug": "rmp64",
    "symbol": "RMP64",
    "name": "ribonuclease MRP subunit p64",
    "hgnc": "HGNC:24496",
    "summary": null,
    "location": "3q13.2",
    "locusType": "gene with protein product",
    "aliases": [
      "DKFZP434F2021",
      "NET17"
    ],
    "previousSymbols": [
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      "NEPRO"
    ],
    "ensemblId": "ENSG00000163608",
    "entrezId": 25871,
    "omim": [
      "617089"
    ],
    "uniprot": [
      "Q6NW34"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "3",
      "start": 113002444,
      "end": 113019671,
      "strand": "-",
      "ensemblTranscript": "ENST00000314400.10",
      "refseqTranscript": "NM_015412.4",
      "ensemblProtein": "ENSP00000320251.5",
      "refseqProtein": "NP_056227.2",
      "exons": [
        {
          "start": 113002444,
          "end": 113006004
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        {
          "start": 113008171,
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        },
        {
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        {
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        },
        {
          "start": 113017448,
          "end": 113017602
        },
        {
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          "end": 113019671
        }
      ],
      "cds": {
        "start": 113005536,
        "end": 113019647
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "3",
      "start": 112721287,
      "end": 112738708,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 112511058,
      "end": 113511057,
      "genes": [
        {
          "symbol": "ATG3",
          "ensemblId": "ENSG00000144848",
          "biotype": "protein_coding",
          "start": 112531772,
          "end": 112562318,
          "strand": "-",
          "slug": "atg3"
        },
        {
          "symbol": "SLC35A5",
          "ensemblId": "ENSG00000138459",
          "biotype": "protein_coding",
          "start": 112561269,
          "end": 112587350,
          "strand": "+",
          "slug": "slc35a5"
        },
        {
          "symbol": "CCDC80",
          "ensemblId": "ENSG00000091986",
          "biotype": "protein_coding",
          "start": 112596797,
          "end": 112649530,
          "strand": "-",
          "slug": "ccdc80"
        },
        {
          "symbol": "CD200R1L",
          "ensemblId": "ENSG00000206531",
          "biotype": "protein_coding",
          "start": 112815709,
          "end": 112846864,
          "strand": "-",
          "slug": "cd200r1l"
        },
        {
          "symbol": "CD200R1",
          "ensemblId": "ENSG00000163606",
          "biotype": "protein_coding",
          "start": 112921058,
          "end": 112975103,
          "strand": "-",
          "slug": "cd200r1"
        },
        {
          "symbol": "GTPBP8",
          "ensemblId": "ENSG00000163607",
          "biotype": "protein_coding",
          "start": 112990909,
          "end": 113015877,
          "strand": "+",
          "slug": "gtpbp8"
        },
        {
          "symbol": "BOC",
          "ensemblId": "ENSG00000144857",
          "biotype": "protein_coding",
          "start": 113210846,
          "end": 113287463,
          "strand": "+",
          "slug": "boc"
        },
        {
          "symbol": "CFAP44",
          "ensemblId": "ENSG00000206530",
          "biotype": "protein_coding",
          "start": 113286930,
          "end": 113441610,
          "strand": "-",
          "slug": "cfap44"
        },
        {
          "symbol": "SPICE1-CFAP44",
          "ensemblId": "ENSG00000285943",
          "biotype": "protein_coding",
          "start": 113361901,
          "end": 113515151,
          "strand": "-",
          "slug": "spice1-cfap44"
        },
        {
          "symbol": "SPICE1",
          "ensemblId": "ENSG00000163611",
          "biotype": "protein_coding",
          "start": 113442718,
          "end": 113515606,
          "strand": "-",
          "slug": "spice1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "gastroesophageal-reflux",
        "name": "Acid reflux",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/gastroesophageal-reflux"
      },
      {
        "slug": "plagiocephaly",
        "name": "Asymmetry of the posterior head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/plagiocephaly"
      },
      {
        "slug": "beaking-of-vertebral-bodies",
        "name": "Beaking of vertebral bodies",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/beaking-of-vertebral-bodies"
      },
      {
        "slug": "femoral-bowing",
        "name": "Bowed thighbone",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/femoral-bowing"
      },
      {
        "slug": "broad-eyebrow",
        "name": "Broad eyebrow",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/broad-eyebrow"
      },
      {
        "slug": "broad-middle-phalanx-of-finger",
        "name": "Broad middle finger bones",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/broad-middle-phalanx-of-finger"
      },
      {
        "slug": "depressed-nasal-bridge",
        "name": "Depressed nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/depressed-nasal-bridge"
      },
      {
        "slug": "joint-hypermobility",
        "name": "Double-Jointed",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/joint-hypermobility"
      },
      {
        "slug": "oligodontia",
        "name": "Failure of development of more than six teeth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/oligodontia"
      },
      {
        "slug": "feeding-difficulties",
        "name": "Feeding difficulties",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/feeding-difficulties"
      },
      {
        "slug": "platyspondyly",
        "name": "Flattened vertebrae",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/platyspondyly"
      },
      {
        "slug": "pectus-excavatum",
        "name": "Funnel chest",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/pectus-excavatum"
      },
      {
        "slug": "generalized-hypotonia",
        "name": "Generalized decreased muscle tone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/generalized-hypotonia"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "cutis-laxa",
        "name": "Hanging skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/cutis-laxa"
      },
      {
        "slug": "high-anterior-hairline",
        "name": "High frontal hairline",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/high-anterior-hairline"
      },
      {
        "slug": "genu-valgum",
        "name": "Knock knees",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/genu-valgum"
      },
      {
        "slug": "metaphyseal-cupping",
        "name": "Metaphyseal cupping",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/metaphyseal-cupping"
      },
      {
        "slug": "midface-retrusion",
        "name": "Midface retrusion",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/midface-retrusion"
      },
      {
        "slug": "motor-delay",
        "name": "Motor delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/motor-delay"
      },
      {
        "slug": "narrow-chest",
        "name": "Narrow chest",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/narrow-chest"
      },
      {
        "slug": "hip-subluxation",
        "name": "Partial hip dislocation",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hip-subluxation"
      },
      {
        "slug": "spinal-cord-compression",
        "name": "Pressure on spinal cord",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/spinal-cord-compression"
      },
      {
        "slug": "retrognathia",
        "name": "Receding chin",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/retrognathia"
      },
      {
        "slug": "recurrent-respiratory-infections",
        "name": "Recurrent respiratory infections",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/recurrent-respiratory-infections"
      },
      {
        "slug": "severe-short-stature",
        "name": "Severe short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/severe-short-stature"
      },
      {
        "slug": "brachydactyly",
        "name": "Short fingers or toes",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/brachydactyly"
      },
      {
        "slug": "short-middle-phalanx-of-finger",
        "name": "Short middle bone of finger",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-middle-phalanx-of-finger"
      },
      {
        "slug": "short-metacarpal",
        "name": "Shortened long bone of hand",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-metacarpal"
      },
      {
        "slug": "small-nail",
        "name": "Small nail",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/small-nail"
      },
      {
        "slug": "sparse-scalp-hair",
        "name": "Sparse scalp hair",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/sparse-scalp-hair"
      },
      {
        "slug": "squared-iliac-bones",
        "name": "Squared iliac bones",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/squared-iliac-bones"
      },
      {
        "slug": "thoracolumbar-kyphoscoliosis",
        "name": "Thoracolumbar kyphoscoliosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/thoracolumbar-kyphoscoliosis"
      },
      {
        "slug": "trident-hand",
        "name": "Trident hand",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/trident-hand"
      },
      {
        "slug": "wide-anterior-fontanel",
        "name": "Wider-than-typical soft spot of skull",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/wide-anterior-fontanel"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}