{
  "url": "https://dantelabs.com/el/genes/gpr68",
  "gene": {
    "slug": "gpr68",
    "symbol": "GPR68",
    "name": "G protein-coupled receptor 68",
    "hgnc": "HGNC:4519",
    "summary": null,
    "location": "14q32.11",
    "locusType": "gene with protein product",
    "aliases": [
      "OGR1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000119714",
    "entrezId": 8111,
    "omim": [
      "601404"
    ],
    "uniprot": [
      "Q15743"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "14",
      "start": 91232532,
      "end": 91244704,
      "strand": "-",
      "ensemblTranscript": "ENST00000650645.1",
      "refseqTranscript": "NM_001177676.2",
      "ensemblProtein": "ENSP00000498702.1",
      "refseqProtein": "NP_001171147.1",
      "exons": [
        {
          "start": 91232532,
          "end": 91235179
        },
        {
          "start": 91244297,
          "end": 91244704
        }
      ],
      "cds": {
        "start": 91233953,
        "end": 91235050
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "14",
      "start": 91698876,
      "end": 91720269,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 90738618,
      "end": 91738617,
      "genes": [
        {
          "symbol": "TTC7B",
          "ensemblId": "ENSG00000165914",
          "biotype": "protein_coding",
          "start": 90524564,
          "end": 90816525,
          "strand": "-",
          "slug": "ttc7b"
        },
        {
          "symbol": "RPS6KA5",
          "ensemblId": "ENSG00000100784",
          "biotype": "protein_coding",
          "start": 90847861,
          "end": 91060685,
          "strand": "-",
          "slug": "rps6ka5"
        },
        {
          "symbol": "DGLUCY",
          "ensemblId": "ENSG00000133943",
          "biotype": "protein_coding",
          "start": 91060044,
          "end": 91226930,
          "strand": "+",
          "slug": "dglucy"
        },
        {
          "symbol": "CCDC88C",
          "ensemblId": "ENSG00000015133",
          "biotype": "protein_coding",
          "start": 91271323,
          "end": 91417890,
          "strand": "-",
          "slug": "ccdc88c"
        },
        {
          "symbol": "PPP4R3A",
          "ensemblId": "ENSG00000100796",
          "biotype": "protein_coding",
          "start": 91457139,
          "end": 91510556,
          "strand": "-",
          "slug": "ppp4r3a"
        },
        {
          "symbol": "CATSPERB",
          "ensemblId": "ENSG00000133962",
          "biotype": "protein_coding",
          "start": 91580696,
          "end": 91780707,
          "strand": "-",
          "slug": "catsperb"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "amelogenesis-imperfecta",
        "name": "Ατελής αμελογένεση",
        "diseases": [
          {
            "mondoId": "MONDO:0019507",
            "name": "ατελής αμελογένεση",
            "genes": 17,
            "inheritance": "autosomal-dominant",
            "description": null,
            "management": null,
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/el/conditions/amelogenesis-imperfecta"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "anterior-open-bite-malocclusion",
        "name": "Absence of overlap of anterior upper and lower teeth",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/anterior-open-bite-malocclusion"
      },
      {
        "slug": "amelogenesis-imperfecta",
        "name": "Amelogenesis imperfecta",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/amelogenesis-imperfecta"
      },
      {
        "slug": "enamel-hypomineralization",
        "name": "Poorly mineralized tooth enamel",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/enamel-hypomineralization"
      }
    ],
    "related": [
      {
        "slug": "acp4",
        "symbol": "ACP4",
        "name": "acid phosphatase 4",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/acp4"
      },
      {
        "slug": "ambn",
        "symbol": "AMBN",
        "name": "ameloblastin",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/ambn"
      },
      {
        "slug": "amelx",
        "symbol": "AMELX",
        "name": "amelogenin X-linked",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/amelx"
      },
      {
        "slug": "dlx3",
        "symbol": "DLX3",
        "name": "distal-less homeobox 3",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/dlx3"
      },
      {
        "slug": "enam",
        "symbol": "ENAM",
        "name": "enamelin",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/enam"
      },
      {
        "slug": "fam20a",
        "symbol": "FAM20A",
        "name": "FAM20A golgi associated secretory pathway pseudokinase",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/fam20a"
      },
      {
        "slug": "itgb6",
        "symbol": "ITGB6",
        "name": "integrin subunit beta 6",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/itgb6"
      },
      {
        "slug": "klk4",
        "symbol": "KLK4",
        "name": "kallikrein related peptidase 4",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/klk4"
      },
      {
        "slug": "lamb3",
        "symbol": "LAMB3",
        "name": "laminin subunit beta 3",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/lamb3"
      },
      {
        "slug": "mmp20",
        "symbol": "MMP20",
        "name": "matrix metallopeptidase 20",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/mmp20"
      },
      {
        "slug": "odaph",
        "symbol": "ODAPH",
        "name": "odontogenesis associated phosphoprotein",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/odaph"
      },
      {
        "slug": "relt",
        "symbol": "RELT",
        "name": "RELT TNF receptor",
        "shared": 1,
        "url": "https://dantelabs.com/el/genes/relt"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}