{
  "url": "https://dantelabs.com/traits/vertical-forehead-creases",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "vertical-forehead-creases",
    "id": "HP:0011221",
    "name": "Vertical forehead creases",
    "definition": "Vertical soft tissue creases in the midline of the forehead, often extending from the hairline to the brow, and seen with facial expression or when the face is at rest.",
    "synonyms": [
      "Frontal creases of face",
      "Vertical forehead wrinkles",
      "Vertical forehead rhytids"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-forehead-morphology",
        "name": "Abnormality of the forehead",
        "url": "https://dantelabs.com/traits/abnormal-forehead-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "pigs",
        "symbol": "PIGS",
        "hgnc": "HGNC:14937",
        "name": "phosphatidylinositol glycan anchor biosynthesis class S",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pigs"
      },
      {
        "slug": "aff4",
        "symbol": "AFF4",
        "hgnc": "HGNC:17869",
        "name": "ALF transcription elongation factor 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aff4"
      }
    ]
  }
}