{
  "url": "https://dantelabs.com/traits/third-heart-sound",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "third-heart-sound",
    "id": "HP:0031658",
    "name": "Third heart sound",
    "definition": "The third heart sound (S3) is related to rapid filling in diastole. S3 can be a normal finding in children and adolescents but suggests heart failure in older patients.",
    "synonyms": [
      "S3",
      "Ventricular gallop"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "gallop-rhythm",
        "name": "Gallop rhythm",
        "url": "https://dantelabs.com/traits/gallop-rhythm"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "tll1",
        "symbol": "TLL1",
        "hgnc": "HGNC:11843",
        "name": "tolloid like 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tll1"
      }
    ]
  }
}