{
  "url": "https://dantelabs.com/traits/t-wave-inversion",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "t-wave-inversion",
    "id": "HP:0010872",
    "name": "T-wave inversion",
    "definition": "An inversion of the T-wave (which is normally positive).",
    "synonyms": [
      "EKG: T-wave inversion"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-t-wave",
        "name": "Abnormal T-wave",
        "url": "https://dantelabs.com/traits/abnormal-t-wave"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "emd",
        "symbol": "EMD",
        "hgnc": "HGNC:3331",
        "name": "emerin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/emd"
      },
      {
        "slug": "gyg1",
        "symbol": "GYG1",
        "hgnc": "HGNC:4699",
        "name": "glycogenin 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gyg1"
      },
      {
        "slug": "hcn4",
        "symbol": "HCN4",
        "hgnc": "HGNC:16882",
        "name": "hyperpolarization activated cyclic nucleotide gated potassium channel 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcn4"
      },
      {
        "slug": "jup",
        "symbol": "JUP",
        "hgnc": "HGNC:6207",
        "name": "junction plakoglobin",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/jup"
      },
      {
        "slug": "myl3",
        "symbol": "MYL3",
        "hgnc": "HGNC:7584",
        "name": "myosin light chain 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myl3"
      },
      {
        "slug": "tgfb3",
        "symbol": "TGFB3",
        "hgnc": "HGNC:11769",
        "name": "transforming growth factor beta 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tgfb3"
      },
      {
        "slug": "myl2",
        "symbol": "MYL2",
        "hgnc": "HGNC:7583",
        "name": "myosin light chain 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myl2"
      },
      {
        "slug": "prkag2",
        "symbol": "PRKAG2",
        "hgnc": "HGNC:9386",
        "name": "protein kinase AMP-activated non-catalytic subunit gamma 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkag2"
      }
    ]
  }
}