{
  "url": "https://dantelabs.com/traits/sleep-onset-insomnia",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "sleep-onset-insomnia",
    "id": "HP:0031354",
    "name": "Difficulty falling asleep",
    "label": "Sleep onset insomnia",
    "definition": "Difficulty initiating sleep, that is, increased sleep onset latency, refers to the condition where it takes 30 minutes or more to fall asleep.",
    "synonyms": [
      "Early insomnia",
      "Increased sleep latency",
      "Trouble falling asleep"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "insomnia",
        "name": "Difficulty staying or falling asleep",
        "url": "https://dantelabs.com/traits/insomnia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "jkamp",
        "symbol": "JKAMP",
        "hgnc": "HGNC:20184",
        "name": "JNK1/MAPK8 associated membrane protein",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jkamp"
      },
      {
        "slug": "kics2",
        "symbol": "KICS2",
        "hgnc": "HGNC:26517",
        "name": "KICSTOR subunit 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kics2"
      },
      {
        "slug": "lrrc7",
        "symbol": "LRRC7",
        "hgnc": "HGNC:18531",
        "name": "leucine rich repeat containing 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrrc7"
      },
      {
        "slug": "pi4k2a",
        "symbol": "PI4K2A",
        "hgnc": "HGNC:30031",
        "name": "phosphatidylinositol 4-kinase type 2 alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pi4k2a"
      },
      {
        "slug": "chd8",
        "symbol": "CHD8",
        "hgnc": "HGNC:20153",
        "name": "chromodomain helicase DNA binding protein 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd8"
      },
      {
        "slug": "fbxo11",
        "symbol": "FBXO11",
        "hgnc": "HGNC:13590",
        "name": "F-box protein 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo11"
      },
      {
        "slug": "gns",
        "symbol": "GNS",
        "hgnc": "HGNC:4422",
        "name": "glucosamine (N-acetyl)-6-sulfatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gns"
      },
      {
        "slug": "prr12",
        "symbol": "PRR12",
        "hgnc": "HGNC:29217",
        "name": "proline rich 12",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prr12"
      },
      {
        "slug": "kmt5b",
        "symbol": "KMT5B",
        "hgnc": "HGNC:24283",
        "name": "lysine methyltransferase 5B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kmt5b"
      },
      {
        "slug": "cry1",
        "symbol": "CRY1",
        "hgnc": "HGNC:2384",
        "name": "cryptochrome circadian regulator 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cry1"
      }
    ]
  }
}