{
  "url": "https://dantelabs.com/traits/retinoschisis",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "retinoschisis",
    "id": "HP:0030502",
    "name": "Retinoschisis",
    "definition": "Splitting of the neuroretinal layers of the retina.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-retinal-morphology",
        "name": "Retina issue",
        "url": "https://dantelabs.com/traits/abnormal-retinal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "foveoschisis",
        "name": "Foveoschisis",
        "genes": 2,
        "url": "https://dantelabs.com/traits/foveoschisis"
      }
    ],
    "genes": [
      {
        "slug": "rs1",
        "symbol": "RS1",
        "hgnc": "HGNC:10457",
        "name": "retinoschisin 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rs1"
      },
      {
        "slug": "actb",
        "symbol": "ACTB",
        "hgnc": "HGNC:132",
        "name": "actin beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actb"
      },
      {
        "slug": "actg1",
        "symbol": "ACTG1",
        "hgnc": "HGNC:144",
        "name": "actin gamma 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actg1"
      },
      {
        "slug": "gfpt1",
        "symbol": "GFPT1",
        "hgnc": "HGNC:4241",
        "name": "glutamine--fructose-6-phosphate transaminase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gfpt1"
      },
      {
        "slug": "clcn2",
        "symbol": "CLCN2",
        "hgnc": "HGNC:2020",
        "name": "chloride voltage-gated channel 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcn2"
      },
      {
        "slug": "nr2e3",
        "symbol": "NR2E3",
        "hgnc": "HGNC:7974",
        "name": "nuclear receptor subfamily 2 group E member 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr2e3"
      }
    ]
  }
}