{
  "url": "https://dantelabs.com/traits/renal-malrotation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "renal-malrotation",
    "id": "HP:0004712",
    "name": "Abnormal rotation of the kidneys",
    "label": "Renal malrotation",
    "definition": "An abnormality of the normal developmental rotation of the kidney leading to an abnormal orientation of the kidney.",
    "synonyms": [
      "Malrotation of the kidney"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-renal-morphology",
        "name": "Abnormally shaped kidney",
        "url": "https://dantelabs.com/traits/abnormal-renal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "axial-malrotation-of-the-kidney",
        "name": "Axial malrotation of the kidney",
        "genes": 1,
        "url": "https://dantelabs.com/traits/axial-malrotation-of-the-kidney"
      }
    ],
    "genes": [
      {
        "slug": "fibp",
        "symbol": "FIBP",
        "hgnc": "HGNC:3705",
        "name": "FGF1 intracellular binding protein",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fibp"
      },
      {
        "slug": "rbm8a",
        "symbol": "RBM8A",
        "hgnc": "HGNC:9905",
        "name": "RNA binding motif protein 8A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbm8a"
      },
      {
        "slug": "sall4",
        "symbol": "SALL4",
        "hgnc": "HGNC:15924",
        "name": "spalt like transcription factor 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sall4"
      },
      {
        "slug": "sox11",
        "symbol": "SOX11",
        "hgnc": "HGNC:11191",
        "name": "SRY-box transcription factor 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox11"
      },
      {
        "slug": "pax2",
        "symbol": "PAX2",
        "hgnc": "HGNC:8616",
        "name": "paired box 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax2"
      },
      {
        "slug": "eya1",
        "symbol": "EYA1",
        "hgnc": "HGNC:3519",
        "name": "EYA transcriptional coactivator and phosphatase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eya1"
      },
      {
        "slug": "six1",
        "symbol": "SIX1",
        "hgnc": "HGNC:10887",
        "name": "SIX homeobox 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/six1"
      },
      {
        "slug": "stra6",
        "symbol": "STRA6",
        "hgnc": "HGNC:30650",
        "name": "signaling receptor and transporter of retinol STRA6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stra6"
      }
    ]
  }
}