{
  "url": "https://dantelabs.com/traits/reduced-coagulation-factor-v-activity",
  "trait": {
    "bundleId": "2026.10.21-777c9289",
    "release": "2026-09-01",
    "slug": "reduced-coagulation-factor-v-activity",
    "id": "HP:0003225",
    "name": "Reduced coagulation factor V activity",
    "definition": "Decreased activity of coagulation factor V.",
    "synonyms": [
      "Reduced factor V activity"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-coagulation-factor-v-activity",
        "name": "Abnormal coagulation factor V activity",
        "url": "https://dantelabs.com/traits/abnormal-coagulation-factor-v-activity"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lman1",
        "symbol": "LMAN1",
        "hgnc": "HGNC:6631",
        "name": "lectin, mannose binding 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lman1"
      },
      {
        "slug": "mcfd2",
        "symbol": "MCFD2",
        "hgnc": "HGNC:18451",
        "name": "multiple coagulation factor deficiency 2, ER cargo receptor complex subunit",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/mcfd2"
      },
      {
        "slug": "slc37a4",
        "symbol": "SLC37A4",
        "hgnc": "HGNC:4061",
        "name": "solute carrier family 37 member 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc37a4"
      },
      {
        "slug": "f5",
        "symbol": "F5",
        "hgnc": "HGNC:3542",
        "name": "coagulation factor V",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/f5"
      }
    ]
  }
}