{
  "url": "https://dantelabs.com/traits/pleural-thickening",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "pleural-thickening",
    "id": "HP:0031944",
    "name": "Pleural thickening",
    "definition": "An increase in the thickness of the pleura, generally related to scarring of the pleural tissue.",
    "synonyms": [
      "Pleural incrassation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-pleura-morphology",
        "name": "Abnormal pleura morphology",
        "url": "https://dantelabs.com/traits/abnormal-pleura-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "nhej1",
        "symbol": "NHEJ1",
        "hgnc": "HGNC:25737",
        "name": "non-homologous end joining factor 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nhej1"
      },
      {
        "slug": "card10",
        "symbol": "CARD10",
        "hgnc": "HGNC:16422",
        "name": "caspase recruitment domain family member 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/card10"
      },
      {
        "slug": "mdfic",
        "symbol": "MDFIC",
        "hgnc": "HGNC:28870",
        "name": "MyoD family inhibitor domain containing",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdfic"
      },
      {
        "slug": "slc34a2",
        "symbol": "SLC34A2",
        "hgnc": "HGNC:11020",
        "name": "solute carrier family 34 member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc34a2"
      }
    ]
  }
}