{
  "url": "https://dantelabs.com/traits/insulin-insensitivity",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "insulin-insensitivity",
    "id": "HP:0008189",
    "name": "Insulin insensitivity",
    "definition": "Decreased sensitivity toward insulin.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-glucose-homeostasis",
        "name": "Abnormal glucose homeostasis",
        "url": "https://dantelabs.com/traits/abnormal-glucose-homeostasis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cnbp",
        "symbol": "CNBP",
        "hgnc": "HGNC:13164",
        "name": "CCHC-type zinc finger nucleic acid binding protein",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cnbp"
      },
      {
        "slug": "igfals",
        "symbol": "IGFALS",
        "hgnc": "HGNC:5468",
        "name": "insulin like growth factor binding protein acid labile subunit",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/igfals"
      },
      {
        "slug": "ar",
        "symbol": "AR",
        "hgnc": "HGNC:644",
        "name": "androgen receptor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ar"
      }
    ]
  }
}