{
  "url": "https://dantelabs.com/traits/heavy-proteinuria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "heavy-proteinuria",
    "id": "HP:0012597",
    "name": "Severely high blood protein levels",
    "label": "Heavy proteinuria",
    "definition": "Severely increased levels of protein in the urine (1000-3000 mg per day in adults).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      }
    ],
    "broader": [
      {
        "slug": "proteinuria",
        "name": "High urine protein levels",
        "url": "https://dantelabs.com/traits/proteinuria"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "vps33a",
        "symbol": "VPS33A",
        "hgnc": "HGNC:18179",
        "name": "VPS33A core subunit of CORVET and HOPS complexes",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps33a"
      }
    ]
  }
}