{
  "url": "https://dantelabs.com/traits/epidermal-nevus",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "epidermal-nevus",
    "id": "HP:0010816",
    "name": "Epidermal nevus",
    "definition": "Epidermal naevi are due to an overgrowth of the epidermis and may be present at birth (50%) or develop during childhood.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "nevus",
        "name": "Mole",
        "url": "https://dantelabs.com/traits/nevus"
      }
    ],
    "narrower": [
      {
        "slug": "nevus-sebaceous",
        "name": "Nevus sebaceous",
        "genes": 5,
        "url": "https://dantelabs.com/traits/nevus-sebaceous"
      },
      {
        "slug": "verrucous-epidermal-nevus",
        "name": "Verrucous epidermal nevus",
        "genes": 3,
        "url": "https://dantelabs.com/traits/verrucous-epidermal-nevus"
      },
      {
        "slug": "nevus-comedonicus",
        "name": "Nevus comedonicus",
        "genes": 1,
        "url": "https://dantelabs.com/traits/nevus-comedonicus"
      }
    ],
    "genes": [
      {
        "slug": "lemd3",
        "symbol": "LEMD3",
        "hgnc": "HGNC:28887",
        "name": "LEM domain containing 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lemd3"
      },
      {
        "slug": "akt1",
        "symbol": "AKT1",
        "hgnc": "HGNC:391",
        "name": "AKT serine/threonine kinase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/akt1"
      },
      {
        "slug": "pten",
        "symbol": "PTEN",
        "hgnc": "HGNC:9588",
        "name": "phosphatase and tensin homolog",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pten"
      },
      {
        "slug": "nsdhl",
        "symbol": "NSDHL",
        "hgnc": "HGNC:13398",
        "name": "NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nsdhl"
      },
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/pik3ca"
      },
      {
        "slug": "kras",
        "symbol": "KRAS",
        "hgnc": "HGNC:6407",
        "name": "KRas proto-oncogene, GTPase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kras"
      }
    ]
  }
}