{
  "url": "https://dantelabs.com/traits/dysplastic-sacrum",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "dysplastic-sacrum",
    "id": "HP:0008455",
    "name": "Absence of some of the sacral and coccygeal bones",
    "label": "Dysplastic sacrum",
    "definition": "A developmental defect of the sacrum characterized by partial or disordered development of the sacrum in which portions of the sacrum, which normally is formed by fusion of five sacral vertebrae S1-S5, fail to form or fail to form normally.",
    "synonyms": [
      "Partial sacral agenesis",
      "Sacral dysgenesis"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-sacrum-morphology",
        "name": "Abnormal sacrum morphology",
        "url": "https://dantelabs.com/traits/abnormal-sacrum-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "hgnc": "HGNC:12869",
        "name": "zinc finger protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfx"
      },
      {
        "slug": "pam16",
        "symbol": "PAM16",
        "hgnc": "HGNC:29679",
        "name": "presequence translocase associated motor 16",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pam16"
      }
    ]
  }
}