{
  "url": "https://dantelabs.com/traits/cleft-mandible",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cleft-mandible",
    "id": "HP:0010752",
    "name": "Cleft lower jaw",
    "label": "Cleft mandible",
    "definition": "Midline deficiency of the mandible and some or all overlying tissues.",
    "synonyms": [
      "Mandibular cleft"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "midline-defect-of-mandible",
        "name": "Midline defect of mandible",
        "url": "https://dantelabs.com/traits/midline-defect-of-mandible"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "eif4a3",
        "symbol": "EIF4A3",
        "hgnc": "HGNC:18683",
        "name": "eukaryotic translation initiation factor 4A3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/eif4a3"
      }
    ]
  }
}