{
  "url": "https://dantelabs.com/traits/cerulean-cataract",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cerulean-cataract",
    "id": "HP:0007976",
    "name": "Cerulean cataract",
    "definition": "Cerulean cataracts are a kind of congenital cataract having peripheral bluish and white opacifications in concentric layers with occasional central lesions arranged radially. Although the opacities may be observed during fetal development and childhood, usually visual acuity is only mildly reduced until adulthood, when lens extraction is generally necessary.",
    "synonyms": [
      "Cataracts, congenital, cerulean"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "punctate-cataract",
        "name": "Punctate cataract",
        "url": "https://dantelabs.com/traits/punctate-cataract"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "crybb2",
        "symbol": "CRYBB2",
        "hgnc": "HGNC:2398",
        "name": "crystallin beta B2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crybb2"
      },
      {
        "slug": "opa3",
        "symbol": "OPA3",
        "hgnc": "HGNC:8142",
        "name": "outer mitochondrial membrane lipid metabolism regulator OPA3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/opa3"
      },
      {
        "slug": "rtn4ip1",
        "symbol": "RTN4IP1",
        "hgnc": "HGNC:18647",
        "name": "reticulon 4 interacting protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rtn4ip1"
      },
      {
        "slug": "maf",
        "symbol": "MAF",
        "hgnc": "HGNC:6776",
        "name": "MAF bZIP transcription factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/maf"
      }
    ]
  }
}