{
  "url": "https://dantelabs.com/traits/basilar-invagination",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "basilar-invagination",
    "id": "HP:0012366",
    "name": "Basilar invagination",
    "definition": "Projection of the tip of the dens more than 5 mm above a line joining the hard palate to the posterior lip of the foramen magnum (Chamberlain's line) or the tip of the dens is greater than 7 mm above McGregor's line (the back of the hard palate to the lowest point of the occipital squama).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-posterior-cranial-fossa-morphology",
        "name": "Abnormal posterior cranial fossa morphology",
        "url": "https://dantelabs.com/traits/abnormal-posterior-cranial-fossa-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "myf5",
        "symbol": "MYF5",
        "hgnc": "HGNC:7565",
        "name": "myogenic factor 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myf5"
      },
      {
        "slug": "b3galt6",
        "symbol": "B3GALT6",
        "hgnc": "HGNC:17978",
        "name": "beta-1,3-galactosyltransferase 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b3galt6"
      },
      {
        "slug": "dkk1",
        "symbol": "DKK1",
        "hgnc": "HGNC:2891",
        "name": "dickkopf Wnt signaling pathway inhibitor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dkk1"
      },
      {
        "slug": "slf2",
        "symbol": "SLF2",
        "hgnc": "HGNC:17814",
        "name": "SMC5/6 complex localization factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slf2"
      }
    ]
  }
}