{
  "url": "https://dantelabs.com/traits/abnormal-prothrombin-time",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-prothrombin-time",
    "id": "HP:0032199",
    "name": "Abnormal prothrombin time",
    "definition": "Any deviation from the normal amount of time to coagulation in the prothrombin time test, which is a measure of the extrinsic pathway of coagulation. The results of the prothrombin time test are often expressed in terms of the International normalized ratio (INR), which is calculated as a ratio of the patient's prothrombin time (PT) to a control PT standardized for the potency of the thromboplastin reagent developed by the World Health Organization (WHO) using the formula: INR is equal to Patient PT divided by Control PT.",
    "synonyms": [
      "Abnormal PT"
    ],
    "systems": [
      {
        "slug": "abnormality-of-blood-and-blood-forming-tissues",
        "name": "Abnormality of blood and blood-forming tissues",
        "url": "https://dantelabs.com/traits/abnormality-of-blood-and-blood-forming-tissues"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-prothrombin",
        "name": "Abnormality of prothrombin",
        "url": "https://dantelabs.com/traits/abnormality-of-prothrombin"
      }
    ],
    "narrower": [
      {
        "slug": "prolonged-prothrombin-time",
        "name": "Prolonged prothrombin time",
        "genes": 53,
        "url": "https://dantelabs.com/traits/prolonged-prothrombin-time"
      },
      {
        "slug": "decreased-prothrombin-time",
        "name": "Decreased prothrombin time",
        "genes": 2,
        "url": "https://dantelabs.com/traits/decreased-prothrombin-time"
      }
    ],
    "genes": []
  }
}