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"ENSG00000108523", "biotype": "protein_coding", "start": 4939997, "end": 4945223, "strand": "+", "slug": "rnf167" }, { "symbol": "PFN1", "ensemblId": "ENSG00000108518", "biotype": "protein_coding", "start": 4945652, "end": 4950517, "strand": "-", "slug": "pfn1" }, { "symbol": "ENO3", "ensemblId": "ENSG00000108515", "biotype": "protein_coding", "start": 4948034, "end": 4957132, "strand": "+", "slug": "eno3" }, { "symbol": "SPAG7", "ensemblId": "ENSG00000091640", "biotype": "protein_coding", "start": 4959226, "end": 4967835, "strand": "-", "slug": "spag7" }, { "symbol": "CAMTA2", "ensemblId": "ENSG00000108509", "biotype": "protein_coding", "start": 4967992, "end": 4987684, "strand": "-", "slug": "camta2" }, { "symbol": "INCA1", "ensemblId": "ENSG00000196388", "biotype": "protein_coding", "start": 4988130, "end": 4999117, "strand": "-", "slug": "inca1" }, { "symbol": "KIF1C", "ensemblId": "ENSG00000129250", "biotype": "protein_coding", "start": 4997629, "end": 5028401, "strand": "+", "slug": "kif1c" }, { "symbol": "SLC52A1", "ensemblId": "ENSG00000132517", "biotype": "protein_coding", "start": 5032600, "end": 5052009, "strand": "-", "slug": "slc52a1" }, { "symbol": "ZFP3", "ensemblId": "ENSG00000180787", "biotype": "protein_coding", "start": 5078241, "end": 5096376, "strand": "+", "slug": "zfp3" }, { "symbol": "ZNF232", "ensemblId": "ENSG00000167840", "biotype": "protein_coding", "start": 5105269, "end": 5123162, "strand": "-", "slug": "znf232" }, { "symbol": "USP6", "ensemblId": "ENSG00000129204", "biotype": "protein_coding", "start": 5116032, "end": 5175034, "strand": "+", "slug": "usp6" }, { "symbol": "ZNF594", "ensemblId": "ENSG00000180626", "biotype": "protein_coding", "start": 5174019, "end": 5191907, "strand": "-", "slug": "znf594" }, { "symbol": "SCIMP", "ensemblId": "ENSG00000161929", "biotype": "protein_coding", "start": 5208915, "end": 5234869, "strand": "-", "slug": "scimp" } ], "truncated": false }, "reports": [ { "slug": "male-infertility", "name": "Männliche Unfruchtbarkeit", "diseases": [ { "mondoId": "MONDO:0005372", "name": "Männliche Unfruchtbarkeit", "genes": 41, "inheritance": null, "description": "Die Unfähigkeit des Mannes, nach einem bestimmten Zeitraum mit ungeschütztem Geschlechtsverkehr eine Eizelle zu befruchten. Bei der männlichen Sterilität handelt es sich um eine dauerhafte Unfruchtbarkeit.", "management": null, "evidence": { "gencc": [ "Labcorp Genetics (formerly Invitae)", "PanelApp Australia" ], "acmgSf": false, "inheritance": [ "autosomal-recessive" ] }, "sameAsReport": true, "broad": false } ], "url": "https://dantelabs.com/de/conditions/male-infertility" } ], "pharmacogenomics": [], "traits": [], "phenotypes": [ { "slug": "abnormal-spermatogenesis", "name": "Abnormal sperm development", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-spermatogenesis" }, { "slug": "azoospermia", "name": "Absent sperm in semen", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/azoospermia" }, { "slug": "decreased-testicular-size", "name": "Decreased testicular size", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/decreased-testicular-size" }, { "slug": "elevated-circulating-follicle-stimulating-hormone-level", "name": "Elevated circulating follicle stimulating hormone level", "systems": [ "abnormality-of-the-endocrine-system", "abnormality-of-the-nervous-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/elevated-circulating-follicle-stimulating-hormone-level" }, { "slug": "increased-circulating-gonadotropin-level", "name": "Increased circulating gonadotropin level", "systems": [ "abnormality-of-the-endocrine-system", "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/increased-circulating-gonadotropin-level" }, { "slug": "male-infertility", "name": "Male infertility", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/male-infertility" }, { "slug": "non-obstructive-azoospermia", "name": "Non-obstructive azoospermia", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/non-obstructive-azoospermia" }, { "slug": "obstructive-azoospermia", "name": "Obstructive azoospermia", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/obstructive-azoospermia" }, { "slug": "round-spermatid-arrest", "name": "Round spermatid arrest", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/round-spermatid-arrest" } ], "related": [ { "slug": "actl9", "symbol": "ACTL9", "name": "actin like 9", "shared": 1, "url": "https://dantelabs.com/de/genes/actl9" }, { "slug": "armc2", "symbol": "ARMC2", "name": "armadillo repeat containing 2", "shared": 1, "url": "https://dantelabs.com/de/genes/armc2" }, { "slug": "aurkc", "symbol": "AURKC", "name": "aurora kinase C", "shared": 1, "url": "https://dantelabs.com/de/genes/aurkc" }, { "slug": "bcorl1", "symbol": "BCORL1", "name": "BCL6 corepressor like 1", "shared": 1, "url": "https://dantelabs.com/de/genes/bcorl1" }, { "slug": "cfap251", "symbol": "CFAP251", "name": "cilia and flagella associated protein 251", "shared": 1, "url": "https://dantelabs.com/de/genes/cfap251" }, { "slug": "cfap43", "symbol": "CFAP43", "name": "cilia and flagella associated protein 43", "shared": 1, "url": "https://dantelabs.com/de/genes/cfap43" }, { "slug": "dmc1", "symbol": "DMC1", "name": "DNA meiotic recombinase 1", "shared": 1, "url": "https://dantelabs.com/de/genes/dmc1" }, { "slug": "dmrt1", "symbol": "DMRT1", "name": "doublesex and mab-3 related transcription factor 1", "shared": 1, "url": "https://dantelabs.com/de/genes/dmrt1" }, { "slug": "dnah1", "symbol": "DNAH1", "name": "dynein axonemal heavy chain 1", "shared": 1, "url": "https://dantelabs.com/de/genes/dnah1" }, { "slug": "dnah10", "symbol": "DNAH10", "name": "dynein axonemal heavy chain 10", "shared": 1, "url": "https://dantelabs.com/de/genes/dnah10" }, { "slug": "dnah12", "symbol": "DNAH12", "name": "dynein axonemal heavy chain 12", "shared": 1, "url": "https://dantelabs.com/de/genes/dnah12" }, { "slug": "dnah17", "symbol": "DNAH17", "name": "dynein axonemal heavy chain 17", "shared": 1, "url": "https://dantelabs.com/de/genes/dnah17" } ], "sources": { "bundleId": "2026.10.19-9814e911", "panel": "2026-10-19", "acmgSf": "SF v3.2" }, "locusKind": "proteinCoding" }, "variants": { "total": 0, "url": null, "items": [] } }