{
  "url": "https://dantelabs.com/de/genes/serpini1",
  "gene": {
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    "name": "serpin family I member 1",
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      ],
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    },
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            "genes": 171,
            "inheritance": null,
            "description": "Eine Erkrankung des Gehirns, die durch Episoden abnorm gesteigerter neuronaler Entladungen gekennzeichnet ist. Diese führen zu vorübergehenden sensorischen, motorischen oder psychischen Funktionsstörungen und können mit oder ohne Bewusstseinsverlust oder Krämpfe auftreten.",
            "management": null,
            "evidence": {
              "gencc": [
                "Ambry Genetics",
                "ClinGen",
                "Labcorp Genetics (formerly Invitae)",
                "PanelApp Australia"
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              "clingen": "Definitive",
              "acmgSf": false,
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        ],
        "url": "https://dantelabs.com/de/conditions/epilepsy-report"
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        "url": "https://dantelabs.com/traits/abnormality-of-extrapyramidal-motor-function"
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      {
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        "url": "https://dantelabs.com/traits/dementia"
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        "url": "https://dantelabs.com/traits/dysarthria"
      },
      {
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        "url": "https://dantelabs.com/traits/diplopia"
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      {
        "slug": "encephalopathy",
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        "url": "https://dantelabs.com/traits/encephalopathy"
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      {
        "slug": "eosinophilic-neuronal-inclusion-bodies",
        "name": "Eosinophilic neuronal inclusion bodies",
        "systems": [
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/eosinophilic-neuronal-inclusion-bodies"
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      {
        "slug": "seizure",
        "name": "Epilepsy",
        "systems": [
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        "url": "https://dantelabs.com/traits/seizure"
      },
      {
        "slug": "gliosis",
        "name": "Gliosis",
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        "url": "https://dantelabs.com/traits/gliosis"
      },
      {
        "slug": "nystagmus",
        "name": "Involuntary, rapid, rhythmic eye movements",
        "systems": [
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        "url": "https://dantelabs.com/traits/nystagmus"
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      {
        "slug": "myoclonus",
        "name": "Jerking",
        "systems": [
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        "url": "https://dantelabs.com/traits/myoclonus"
      },
      {
        "slug": "neuronal-loss-in-central-nervous-system",
        "name": "Loss of brain cells",
        "systems": [
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        "url": "https://dantelabs.com/traits/neuronal-loss-in-central-nervous-system"
      }
    ],
    "related": [
      {
        "slug": "aars1",
        "symbol": "AARS1",
        "name": "alanyl-tRNA synthetase 1",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/aars1"
      },
      {
        "slug": "abat",
        "symbol": "ABAT",
        "name": "4-aminobutyrate aminotransferase",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/abat"
      },
      {
        "slug": "actl6b",
        "symbol": "ACTL6B",
        "name": "actin like 6B",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/actl6b"
      },
      {
        "slug": "adam22",
        "symbol": "ADAM22",
        "name": "ADAM metallopeptidase domain 22",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/adam22"
      },
      {
        "slug": "aldh7a1",
        "symbol": "ALDH7A1",
        "name": "aldehyde dehydrogenase 7 family member A1",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/aldh7a1"
      },
      {
        "slug": "alg13",
        "symbol": "ALG13",
        "name": "ALG13 UDP-N-acetylglucosaminyltransferase subunit",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/alg13"
      },
      {
        "slug": "ap3b2",
        "symbol": "AP3B2",
        "name": "adaptor related protein complex 3 subunit beta 2",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/ap3b2"
      },
      {
        "slug": "arhgef9",
        "symbol": "ARHGEF9",
        "name": "Cdc42 guanine nucleotide exchange factor 9",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/arhgef9"
      },
      {
        "slug": "arv1",
        "symbol": "ARV1",
        "name": "ARV1 fatty acid homeostasis modulator",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/arv1"
      },
      {
        "slug": "arx",
        "symbol": "ARX",
        "name": "aristaless related homeobox",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/arx"
      },
      {
        "slug": "atp1a2",
        "symbol": "ATP1A2",
        "name": "ATPase Na+/K+ transporting subunit alpha 2",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/atp1a2"
      },
      {
        "slug": "atp1a3",
        "symbol": "ATP1A3",
        "name": "ATPase Na+/K+ transporting subunit alpha 3",
        "shared": 1,
        "url": "https://dantelabs.com/de/genes/atp1a3"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}