{
  "url": "https://dantelabs.com/de/genes/ptpn14",
  "gene": {
    "slug": "ptpn14",
    "symbol": "PTPN14",
    "name": "protein tyrosine phosphatase non-receptor type 14",
    "hgnc": "HGNC:9647",
    "summary": null,
    "location": "1q32.3-q41",
    "locusType": "gene with protein product",
    "aliases": [
      "PEZ",
      "PTPD2"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000152104",
    "entrezId": 5784,
    "omim": [
      "603155"
    ],
    "uniprot": [
      "Q15678"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "1",
      "start": 214348700,
      "end": 214551602,
      "strand": "-",
      "ensemblTranscript": "ENST00000366956.10",
      "refseqTranscript": "NM_005401.5",
      "ensemblProtein": "ENSP00000355923.4",
      "refseqProtein": "NP_005392.2",
      "exons": [
        {
          "start": 214348700,
          "end": 214358050
        },
        {
          "start": 214364512,
          "end": 214364675
        },
        {
          "start": 214369457,
          "end": 214369691
        },
        {
          "start": 214372711,
          "end": 214372839
        },
        {
          "start": 214376219,
          "end": 214376437
        },
        {
          "start": 214377959,
          "end": 214378102
        },
        {
          "start": 214383311,
          "end": 214384788
        },
        {
          "start": 214386844,
          "end": 214386922
        },
        {
          "start": 214390988,
          "end": 214391045
        },
        {
          "start": 214393695,
          "end": 214393777
        },
        {
          "start": 214394899,
          "end": 214394986
        },
        {
          "start": 214397913,
          "end": 214398001
        },
        {
          "start": 214401685,
          "end": 214401772
        },
        {
          "start": 214402883,
          "end": 214402953
        },
        {
          "start": 214411684,
          "end": 214411751
        },
        {
          "start": 214414629,
          "end": 214414726
        },
        {
          "start": 214451805,
          "end": 214451974
        },
        {
          "start": 214464630,
          "end": 214464957
        },
        {
          "start": 214551183,
          "end": 214551602
        }
      ],
      "cds": {
        "start": 214357922,
        "end": 214464803
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "1",
      "start": 214522039,
      "end": 214725792,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 213950151,
      "end": 214950150,
      "genes": [
        {
          "symbol": "PROX1",
          "ensemblId": "ENSG00000117707",
          "biotype": "protein_coding",
          "start": 213982711,
          "end": 214041510,
          "strand": "+",
          "slug": "prox1"
        },
        {
          "symbol": "SMYD2",
          "ensemblId": "ENSG00000143499",
          "biotype": "protein_coding",
          "start": 214280722,
          "end": 214338880,
          "strand": "+",
          "slug": "smyd2"
        },
        {
          "symbol": "CENPF",
          "ensemblId": "ENSG00000117724",
          "biotype": "protein_coding",
          "start": 214603172,
          "end": 214664574,
          "strand": "+",
          "slug": "cenpf"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "choanal-atresia",
        "name": "Blockage of the rear opening of the nasal cavity",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/choanal-atresia"
      },
      {
        "slug": "pericardial-effusion",
        "name": "Fluid around heart",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "url": "https://dantelabs.com/traits/pericardial-effusion"
      },
      {
        "slug": "high-palate",
        "name": "High palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/high-palate"
      },
      {
        "slug": "lymphedema",
        "name": "Swelling caused by excess lymph fluid under skin",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/lymphedema"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}