{
  "url": "https://dantelabs.com/de/genes/ntn1",
  "gene": {
    "slug": "ntn1",
    "symbol": "NTN1",
    "name": "netrin 1",
    "hgnc": "HGNC:8029",
    "summary": null,
    "location": "17p13.1",
    "locusType": "gene with protein product",
    "aliases": [
      "NTN1L",
      "NET1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000065320",
    "entrezId": 9423,
    "omim": [
      "601614"
    ],
    "uniprot": [
      "O95631"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 9021510,
      "end": 9244000,
      "strand": "+",
      "ensemblTranscript": "ENST00000173229.7",
      "refseqTranscript": "NM_004822.3",
      "ensemblProtein": "ENSP00000173229.2",
      "refseqProtein": "NP_004813.2",
      "exons": [
        {
          "start": 9021510,
          "end": 9021585
        },
        {
          "start": 9022311,
          "end": 9023391
        },
        {
          "start": 9162813,
          "end": 9163001
        },
        {
          "start": 9179807,
          "end": 9179956
        },
        {
          "start": 9182916,
          "end": 9182969
        },
        {
          "start": 9221168,
          "end": 9221242
        },
        {
          "start": 9239640,
          "end": 9244000
        }
      ],
      "cds": {
        "start": 9022374,
        "end": 9239968
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 8924859,
      "end": 9147317,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 8632755,
      "end": 9632754,
      "genes": [
        {
          "symbol": "CCDC42",
          "ensemblId": "ENSG00000161973",
          "biotype": "protein_coding",
          "start": 8729930,
          "end": 8745970,
          "strand": "-",
          "slug": "ccdc42"
        },
        {
          "symbol": "SPDYE4",
          "ensemblId": "ENSG00000183318",
          "biotype": "protein_coding",
          "start": 8747524,
          "end": 8758559,
          "strand": "-",
          "slug": "spdye4"
        },
        {
          "symbol": "MFSD6L",
          "ensemblId": "ENSG00000185156",
          "biotype": "protein_coding",
          "start": 8797110,
          "end": 8799365,
          "strand": "-",
          "slug": "mfsd6l"
        },
        {
          "symbol": "PIK3R6",
          "ensemblId": "ENSG00000276231",
          "biotype": "protein_coding",
          "start": 8802722,
          "end": 8867696,
          "strand": "-",
          "slug": "pik3r6"
        },
        {
          "symbol": "PIK3R5",
          "ensemblId": "ENSG00000141506",
          "biotype": "protein_coding",
          "start": 8878911,
          "end": 8966008,
          "strand": "-",
          "slug": "pik3r5"
        },
        {
          "symbol": "STX8",
          "ensemblId": "ENSG00000170310",
          "biotype": "protein_coding",
          "start": 9250149,
          "end": 9576591,
          "strand": "-",
          "slug": "stx8"
        },
        {
          "symbol": "CFAP52",
          "ensemblId": "ENSG00000166596",
          "biotype": "protein_coding",
          "start": 9576627,
          "end": 9643455,
          "strand": "+",
          "slug": "cfap52"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-corticospinal-tract-morphology",
        "name": "Abnormal corticospinal tract morphology",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-corticospinal-tract-morphology"
      },
      {
        "slug": "abnormality-of-movement",
        "name": "Abnormality of movement",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-movement"
      },
      {
        "slug": "agenesis-of-corpus-callosum",
        "name": "Agenesis of corpus callosum",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/agenesis-of-corpus-callosum"
      },
      {
        "slug": "cerebral-palsy",
        "name": "Cerebral palsy",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/cerebral-palsy"
      },
      {
        "slug": "clumsiness",
        "name": "Clumsiness",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/clumsiness"
      },
      {
        "slug": "dysgenesis-of-the-hippocampus",
        "name": "Dysgenesis of the hippocampus",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/dysgenesis-of-the-hippocampus"
      },
      {
        "slug": "fused-cervical-vertebrae",
        "name": "Fused neck",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/fused-cervical-vertebrae"
      },
      {
        "slug": "bimanual-synkinesia",
        "name": "Hand mirror movements",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/bimanual-synkinesia"
      },
      {
        "slug": "hypogonadotropic-hypogonadism",
        "name": "Hypogonadotropic hypogonadism",
        "systems": [
          "abnormality-of-the-endocrine-system",
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hypogonadotropic-hypogonadism"
      },
      {
        "slug": "mild-intellectual-disability",
        "name": "Intellectual disability, mild",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/mild-intellectual-disability"
      },
      {
        "slug": "myalgia",
        "name": "Muscle ache",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/myalgia"
      },
      {
        "slug": "poor-fine-motor-coordination",
        "name": "Poor fine motor coordination",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/poor-fine-motor-coordination"
      },
      {
        "slug": "specific-learning-disability",
        "name": "Specific learning disability",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/specific-learning-disability"
      },
      {
        "slug": "easy-fatigability",
        "name": "Tired easily",
        "systems": [
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/easy-fatigability"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}