{ "url": "https://dantelabs.com/de/genes/gla", "gene": { "slug": "gla", "symbol": "GLA", "name": "galactosidase alpha", "hgnc": "HGNC:4296", "summary": null, "location": "Xq22.1", "locusType": "gene with protein product", "aliases": [ "GALA" ], "previousSymbols": [], "ensemblId": "ENSG00000102393", "entrezId": 2717, "omim": [ "300644" ], "uniprot": [ "P06280" ], "model": { "build": "GRCh38", "release": "v1.5", "chrom": "X", "start": 101397803, "end": 101407925, "strand": "-", "ensemblTranscript": "ENST00000218516.4", "refseqTranscript": "NM_000169.3", "ensemblProtein": "ENSP00000218516.4", "refseqProtein": "NP_000160.1", "exons": [ { "start": 101397803, "end": 101398099 }, { "start": 101398370, "end": 101398567 }, { "start": 101398785, "end": 101398946 }, { "start": 101400666, "end": 101400757 }, { "start": 101401632, "end": 101401809 }, { "start": 101403811, "end": 101403985 }, { "start": 101407710, "end": 101407925 } ], "cds": { "start": 101397809, "end": 101407903 } }, "grch37": { "build": "GRCh37", "release": "87", "chrom": "X", "start": 100652791, "end": 100662913, "strand": "-" }, "neighbourhood": { "release": "116", "start": 100902864, "end": 101902863, "genes": [ { "symbol": "XKRX", "ensemblId": "ENSG00000182489", "biotype": "protein_coding", "start": 100886924, "end": 100929433, "strand": "-", "slug": "xkrx" }, { "symbol": "ARL13A", "ensemblId": "ENSG00000174225", "biotype": "protein_coding", "start": 100969708, "end": 100990831, "strand": "+", "slug": "arl13a" }, { "symbol": "TRMT2B", "ensemblId": "ENSG00000188917", "biotype": "protein_coding", "start": 100973670, "end": 101052135, "strand": "-", "slug": "trmt2b" }, { "symbol": "TMEM35A", "ensemblId": "ENSG00000126950", "biotype": "protein_coding", "start": 101078870, "end": 101096367, "strand": "+", "slug": "tmem35a" }, { "symbol": "CENPI", "ensemblId": "ENSG00000102384", "biotype": "protein_coding", "start": 101098150, "end": 101166126, "strand": "+", "slug": "cenpi" }, { "symbol": "DRP2", "ensemblId": "ENSG00000102385", "biotype": "protein_coding", "start": 101219723, "end": 101264502, "strand": "+", "slug": "drp2" }, { "symbol": "TAF7L", "ensemblId": "ENSG00000102387", "biotype": "protein_coding", "start": 101268253, "end": 101293057, "strand": "-", "slug": "taf7l" }, { "symbol": "TIMM8A", "ensemblId": "ENSG00000126953", "biotype": "protein_coding", "start": 101320050, "end": 101349001, "strand": "-", "slug": "timm8a" }, { "symbol": "BTK", "ensemblId": "ENSG00000010671", "biotype": "protein_coding", "start": 101349338, "end": 101390796, "strand": "-", "slug": "btk" }, { "symbol": "RPL36A", "ensemblId": "ENSG00000241343", "biotype": "protein_coding", "start": 101390824, "end": 101396155, "strand": "+", "slug": "rpl36a" }, { "symbol": "RPL36A-HNRNPH2", "ensemblId": "ENSG00000257529", "biotype": "protein_coding", "start": 101391011, "end": 101412297, "strand": "+", "slug": "rpl36a-hnrnph2" }, { "symbol": "HNRNPH2", "ensemblId": "ENSG00000126945", "biotype": "protein_coding", "start": 101408114, "end": 101414778, "strand": "+", "slug": "hnrnph2" }, { "symbol": "ARMCX4", "ensemblId": "ENSG00000196440", "biotype": "protein_coding", "start": 101418269, "end": 101535551, "strand": "+", "slug": "armcx4" }, { "symbol": "ARMCX1", "ensemblId": "ENSG00000126947", "biotype": "protein_coding", "start": 101550411, "end": 101554704, "strand": "+", "slug": "armcx1" }, { "symbol": "ARMCX6", "ensemblId": "ENSG00000198960", "biotype": "protein_coding", "start": 101615118, "end": 101618011, "strand": "-", "slug": "armcx6" }, { "symbol": "ARMCX3", "ensemblId": "ENSG00000102401", "biotype": "protein_coding", "start": 101622797, "end": 101627843, "strand": "+", "slug": "armcx3" }, { "symbol": "ARMCX2", "ensemblId": "ENSG00000184867", "biotype": "protein_coding", "start": 101654024, "end": 101659924, "strand": "-", "slug": "armcx2" }, { "symbol": "ZMAT1", "ensemblId": "ENSG00000166432", "biotype": "protein_coding", "start": 101882288, "end": 101932090, "strand": "-", "slug": "zmat1" } ], "truncated": false }, "reports": [ { "slug": "fabry-disease", "name": "Morbus Fabry", "diseases": [ { "mondoId": "MONDO:0010526", "name": "Morbus Fabry", "genes": 1, "inheritance": "x-linked-recessive", "description": "Morbus Fabry (FD) ist eine fortschreitende, erbliche, multisystemische lysosomale Speicherkrankheit, die durch spezifische neurologische, kutane, renale, kardiovaskuläre, kochleovestibuläre und zerebrovaskuläre Manifestationen gekennzeichnet ist.", "management": "Enzymersatztherapie (Agalsidase alfa oder Agalsidase beta); Migalastat (Galafold) bei geeigneten GLA-Varianten; Schmerzmanagement (Carbamazepin, Gabapentin); Nephroprotektion mit ACE-Hemmern bzw. AT1-Rezeptorblockern; Management von Herzschrittmachern bzw. Defibrillatoren bei Herzrhythmusstörungen", "evidence": { "gencc": [ "ClinGen", "G2P", "Genomics England PanelApp", "Labcorp Genetics (formerly Invitae)", "Natera" ], "clingen": "Definitive", "acmgSf": true, "inheritance": [], "actionability": 9 }, "sameAsReport": true, "broad": false } ], "url": "https://dantelabs.com/de/conditions/fabry-disease" }, { "slug": "lysosomal-storage-disease", "name": "Lysosomale Speicherkrankheit", "diseases": [ { "mondoId": "MONDO:0002561", "name": "Lysosomale Speicherkrankheit (andere und nicht näher bezeichnete Typen)", "genes": 59, "inheritance": null, "description": "Umfasst lysosomale Speicherkrankheiten ohne eigenen Bericht, etwa die Farber-Krankheit und andere ASAH1-assoziierte Erkrankungen, Defizienzen von Prosaposin (PSAP), die multiple Sulfatase-Defizienz, die Mukopolysaccharidosen Typ IX und X sowie die Dorfman-Chanarin-Krankheit; der Erbgang variiert je nach Subtyp und ist am häufigsten autosomal-rezessiv.", "management": null, "evidence": { "gencc": [ "ClinGen", "G2P", "Genomics England PanelApp", "Labcorp Genetics (formerly Invitae)", "Natera" ], "clingen": "Definitive", "acmgSf": true, "inheritance": [], "actionability": 9 }, "sameAsReport": false, "broad": true } ], "url": "https://dantelabs.com/de/conditions/lysosomal-storage-disease" } ], "pharmacogenomics": [], "traits": [], "phenotypes": [ { "slug": "abdominal-pain", "name": "Abdominal pain", "systems": [ "abnormality-of-the-digestive-system", "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abdominal-pain" }, { "slug": "abnormal-aortic-valve-morphology", "name": "Abnormal aortic valve morphology", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-aortic-valve-morphology" }, { "slug": "abnormal-autonomic-nervous-system-physiology", "name": "Abnormal autonomic nervous system physiology", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/abnormal-autonomic-nervous-system-physiology" }, { "slug": "abnormal-circulating-lipid-concentration", "name": "Abnormal circulating lipid concentration", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-circulating-lipid-concentration" }, { "slug": "abnormal-endocardium-morphology", "name": "Abnormal endocardium morphology", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormal-endocardium-morphology" }, { "slug": "abnormal-glycosphingolipid-metabolism", "name": "Abnormal glycosphingolipid metabolism", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/abnormal-glycosphingolipid-metabolism" }, { "slug": "arrhythmia", "name": "Abnormal heart rate", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/arrhythmia" }, { "slug": "abnormal-myocardium-morphology", "name": "Abnormal myocardium morphology", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormal-myocardium-morphology" }, { "slug": "abnormal-renal-tubule-morphology", "name": "Abnormal renal tubule morphology", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/abnormal-renal-tubule-morphology" }, { "slug": "abnormality-of-the-hand", "name": "Abnormality of the hand", "systems": [ "abnormality-of-limbs" ], "url": "https://dantelabs.com/traits/abnormality-of-the-hand" }, { "slug": "abnormal-femur-morphology", "name": "Abnormality of the thighbone", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/abnormal-femur-morphology" }, { "slug": "achalasia", "name": "Achalasia", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/achalasia" }, { "slug": "acroparesthesia", "name": "Acroparesthesia", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/acroparesthesia" }, { "slug": "angina-pectoris", "name": "Angina pectoris", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/angina-pectoris" }, { "slug": "angiokeratoma", "name": "Angiokeratoma", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/angiokeratoma" }, { "slug": "angiokeratoma-corporis-diffusum", "name": "Angiokeratoma corporis diffusum", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/angiokeratoma-corporis-diffusum" }, { "slug": "anorexia", "name": "Anorexia", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/anorexia" }, { "slug": "anxiety", "name": "Anxiety", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/anxiety" }, { "slug": "arthritis", "name": "Arthritis", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/arthritis" }, { "slug": "atypical-behavior", "name": "Behavioral abnormality", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/atypical-behavior" }, { "slug": "hematuria", "name": "Blood in urine", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/hematuria" }, { "slug": "dyspnea", "name": "Breathing difficulty", "systems": [ "abnormality-of-the-respiratory-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/dyspnea" }, { "slug": "bundle-branch-block", "name": "Bundle branch block", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/bundle-branch-block" }, { "slug": "congestive-heart-failure", "name": "Cardiac failure", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/congestive-heart-failure" }, { "slug": "chronic-pain", "name": "Chronic pain", "systems": [ "constitutional-symptom" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/chronic-pain" }, { "slug": "chronic-pulmonary-obstruction", "name": "Chronic pulmonary obstruction", "systems": [ "abnormality-of-the-respiratory-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/chronic-pulmonary-obstruction" }, { "slug": "cataract", "name": "Clouding of the lens of the eye", "systems": [ "abnormality-of-the-eye" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/cataract" }, { "slug": "coarse-facial-features", "name": "Coarse facial features", "systems": [ "abnormality-of-head-or-neck" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/coarse-facial-features" }, { "slug": "cognitive-impairment", "name": "Cognitive impairment", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/cognitive-impairment" }, { "slug": "cornea-verticillata", "name": "Cornea verticillata", "systems": [ "abnormality-of-the-eye" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/cornea-verticillata" }, { "slug": "corneal-dystrophy", "name": "Corneal dystrophy", "systems": [ "abnormality-of-the-eye" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/corneal-dystrophy" }, { "slug": "corneal-opacity", "name": "Corneal opacity", "systems": [ "abnormality-of-the-eye" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/corneal-opacity" }, { "slug": "exercise-intolerance", "name": "Decreased ability to exercise", "systems": [ "constitutional-symptom" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/exercise-intolerance" }, { "slug": "hypohidrosis", "name": "Decreased ability to sweat", "systems": [ "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/hypohidrosis" }, { "slug": "decreased-alpha-galactosidase-a-activity", "name": "Decreased alpha-galactosidase A activity", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/decreased-alpha-galactosidase-a-activity" }, { "slug": "delayed-puberty", "name": "Delayed puberty", "systems": [ "abnormality-of-the-endocrine-system", "growth-abnormality" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/delayed-puberty" }, { "slug": "depression", "name": "Depression", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/depression" }, { "slug": "diabetes-insipidus", "name": "Diabetes insipidus", "systems": [ "abnormality-of-the-endocrine-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/diabetes-insipidus" }, { "slug": "diarrhea", "name": "Diarrhea", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/diarrhea" }, { "slug": "vertigo", "name": "Dizziness", "systems": [ "abnormality-of-the-ear" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/vertigo" }, { "slug": "elevated-circulating-globotriaosylceramide-concentration", "name": "Elevated circulating globotriaosylceramide concentration", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/elevated-circulating-globotriaosylceramide-concentration" }, { "slug": "hyperlipidemia", "name": "Elevated lipids in blood", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/hyperlipidemia" }, { "slug": "emphysema", "name": "Emphysema", "systems": [ "abnormality-of-the-respiratory-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/emphysema" }, { "slug": "hypertrophic-cardiomyopathy", "name": "Enlarged and thickened heart muscle", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hypertrophic-cardiomyopathy" }, { "slug": "seizure", "name": "Epilepsy", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/seizure" }, { "slug": "hyperhidrosis", "name": "Excessive sweating", "systems": [ "abnormality-of-the-integument" ], "frequency": "very-rare", "url": "https://dantelabs.com/traits/hyperhidrosis" }, { "slug": "fatigue", "name": "Fatigue", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/fatigue" }, { "slug": "fever", "name": "Fever", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/fever" }, { "slug": "subcutaneous-nodule", "name": "Firm lump under the skin", "systems": [ "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/subcutaneous-nodule" }, { "slug": "thick-lower-lip-vermilion", "name": "Full lower lip", "systems": [ "abnormality-of-head-or-neck" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/thick-lower-lip-vermilion" }, { "slug": "glomerulopathy", "name": "Glomerulopathy", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/glomerulopathy" }, { "slug": "hearing-impairment", "name": "Hearing impairment", "systems": [ "abnormality-of-the-ear" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/hearing-impairment" }, { "slug": "myocardial-infarction", "name": "Heart attack", "systems": [ "abnormality-of-the-cardiovascular-system" ], "url": "https://dantelabs.com/traits/myocardial-infarction" }, { "slug": "heat-intolerance", "name": "Heat intolerance", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/heat-intolerance" }, { "slug": "hypertension", "name": "High blood pressure", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/hypertension" }, { "slug": "proteinuria", "name": "High urine protein levels", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/proteinuria" }, { "slug": "hyperkeratosis", "name": "Hyperkeratosis", "systems": [ "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/hyperkeratosis" }, { "slug": "atrioventricular-block", "name": "Interruption of electrical communication between upper and lower chambers of heart", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/atrioventricular-block" }, { "slug": "arthralgia", "name": "Joint pain", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/arthralgia" }, { "slug": "nephropathy", "name": "Kidney damage", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/nephropathy" }, { "slug": "left-ventricular-hypertrophy", "name": "Left ventricular hypertrophy", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/left-ventricular-hypertrophy" }, { "slug": "lipiduria", "name": "Lipiduria", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "url": "https://dantelabs.com/traits/lipiduria" }, { "slug": "developmental-regression", "name": "Loss of developmental milestones", "systems": [ "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/developmental-regression" }, { "slug": "anemia", "name": "Low number of red blood cells or hemoglobin", "systems": [ "abnormality-of-blood-and-blood-forming-tissues" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/anemia" }, { "slug": "reduced-bone-mineral-density", "name": "Low solidness and mass of the bones", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/reduced-bone-mineral-density" }, { "slug": "malabsorption", "name": "Malabsorption", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/malabsorption" }, { "slug": "transient-ischemic-attack", "name": "Mini stroke", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-nervous-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/transient-ischemic-attack" }, { "slug": "mitral-regurgitation", "name": "Mitral regurgitation", "systems": [ "abnormality-of-the-cardiovascular-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/mitral-regurgitation" }, { "slug": "mucosal-telangiectasiae", "name": "Mucosal telangiectasiae", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/mucosal-telangiectasiae" }, { "slug": "myalgia", "name": "Muscle ache", "systems": [ "constitutional-symptom" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/myalgia" }, { "slug": "muscle-spasm", "name": "Muscle spasm", "systems": [ "abnormality-of-the-musculoskeletal-system" ], "url": "https://dantelabs.com/traits/muscle-spasm" }, { "slug": "fasciculations", "name": "Muscle twitch", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/fasciculations" }, { "slug": "nausea", "name": "Nausea", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/nausea" }, { "slug": "nausea-and-vomiting", "name": "Nausea and vomiting", "systems": [ "abnormality-of-the-digestive-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/nausea-and-vomiting" }, { "slug": "nephrotic-syndrome", "name": "Nephrotic syndrome", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/nephrotic-syndrome" }, { "slug": "airway-obstruction", "name": "Obstructive lung disease", "systems": [ "abnormality-of-the-respiratory-system" ], "url": "https://dantelabs.com/traits/airway-obstruction" }, { "slug": "optic-atrophy", "name": "Optic atrophy", "systems": [ "abnormality-of-the-eye" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/optic-atrophy" }, { "slug": "paresthesia", "name": "Pins and needles feeling", "systems": [ "abnormality-of-the-nervous-system" ], "url": "https://dantelabs.com/traits/paresthesia" }, { "slug": "renal-insufficiency", "name": "Renal failure", "systems": [ "abnormality-of-the-genitourinary-system" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/renal-insufficiency" }, { "slug": "respiratory-insufficiency", "name": "Respiratory function loss", "systems": [ "abnormality-of-the-respiratory-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/respiratory-insufficiency" }, { "slug": "tinnitus", "name": "Ringing in ears", "systems": [ "abnormality-of-the-ear" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/tinnitus" }, { "slug": "sensorineural-hearing-impairment", "name": "Sensorineural hearing impairment", "systems": [ "abnormality-of-the-ear" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment" }, { "slug": "short-stature", "name": "Short stature", "systems": [ "growth-abnormality" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/short-stature" }, { "slug": "conjunctival-telangiectasia", "name": "Small dilated blood vessels near membrane covering front of eye and eyelids", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-cardiovascular-system", "abnormality-of-the-eye", "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/conjunctival-telangiectasia" }, { "slug": "stroke", "name": "Stroke", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-nervous-system" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/stroke" }, { "slug": "lymphedema", "name": "Swelling caused by excess lymph fluid under skin", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/lymphedema" }, { "slug": "telangiectasia-of-the-skin", "name": "Telangiectasia of the skin", "systems": [ "abnormality-of-the-cardiovascular-system", "abnormality-of-the-integument" ], "frequency": "very-frequent", "url": "https://dantelabs.com/traits/telangiectasia-of-the-skin" }, { "slug": "tenesmus", "name": "Tenesmus", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/tenesmus" }, { "slug": "urinary-mulberry-cells", "name": "Urinary mulberry cells", "systems": [ "abnormality-of-metabolism-homeostasis", "abnormality-of-the-genitourinary-system" ], "url": "https://dantelabs.com/traits/urinary-mulberry-cells" }, { "slug": "ventricular-septal-hypertrophy", "name": "Ventricular septal hypertrophy", "systems": [ "abnormality-of-the-cardiovascular-system" ], "url": "https://dantelabs.com/traits/ventricular-septal-hypertrophy" }, { "slug": "vomiting", "name": "Vomiting", "systems": [ "abnormality-of-the-digestive-system" ], "url": "https://dantelabs.com/traits/vomiting" } ], "related": [ { "slug": "abhd5", "symbol": "ABHD5", "name": "abhydrolase domain containing 5, lysophosphatidic acid acyltransferase", "shared": 1, "url": "https://dantelabs.com/de/genes/abhd5" }, { "slug": "aga", "symbol": "AGA", "name": "aspartylglucosaminidase", "shared": 1, "url": "https://dantelabs.com/de/genes/aga" }, { "slug": "ap5z1", "symbol": "AP5Z1", "name": "adaptor related protein complex 5 subunit zeta 1", "shared": 1, "url": "https://dantelabs.com/de/genes/ap5z1" }, { "slug": "arsa", "symbol": "ARSA", "name": "arylsulfatase A", "shared": 1, "url": "https://dantelabs.com/de/genes/arsa" }, { "slug": "arsb", "symbol": "ARSB", "name": "arylsulfatase B", "shared": 1, "url": "https://dantelabs.com/de/genes/arsb" }, { "slug": "arsk", "symbol": "ARSK", "name": "arylsulfatase family member K", "shared": 1, "url": "https://dantelabs.com/de/genes/arsk" }, { "slug": "asah1", "symbol": "ASAH1", "name": "N-acylsphingosine amidohydrolase 1", "shared": 1, "url": "https://dantelabs.com/de/genes/asah1" }, { "slug": "clcn6", "symbol": "CLCN6", "name": "Cl-/H+ antiporter 6", "shared": 1, "url": "https://dantelabs.com/de/genes/clcn6" }, { "slug": "cln3", "symbol": "CLN3", "name": "CLN3 lysosomal/endosomal transmembrane protein, battenin", "shared": 1, "url": "https://dantelabs.com/de/genes/cln3" }, { "slug": "cln5", "symbol": "CLN5", "name": "CLN5 lysosomal BMP synthase", "shared": 1, "url": "https://dantelabs.com/de/genes/cln5" }, { "slug": "cln6", "symbol": "CLN6", "name": "CLN6 transmembrane ER protein", "shared": 1, "url": "https://dantelabs.com/de/genes/cln6" }, { "slug": "cln8", "symbol": "CLN8", "name": "CLN8 transmembrane ER and ERGIC protein", "shared": 1, "url": "https://dantelabs.com/de/genes/cln8" } ], "sources": { "bundleId": "2026.10.18-8b139e39", "panel": "2026-10-18", "acmgSf": "SF v3.2" }, "locusKind": "proteinCoding" }, "variants": { "total": 364, "url": "https://dantelabs.com/genes/gla/variants", "items": [ { "slug": "a15e", "name": "A15E", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.44C>A", "position": 101407860, "grch37Position": 100662848, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a15e" }, { "slug": "a20d", "name": "A20D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.59C>A", "position": 101407845, "grch37Position": 100662833, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a20d" }, { "slug": "a20gfs2", "name": "A20Gfs*2", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.59_84del", "position": 101407819, "grch37Position": 100662807, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a20gfs2" }, { "slug": "a29gfs2", "name": "A29Gfs*2", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.85dup", "position": 101407818, "grch37Position": 100662806, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a29gfs2" }, { "slug": "a31v", "name": "A31V", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.92C>T", "position": 101407812, "grch37Position": 100662800, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a31v" }, { "slug": "a37p", "name": "A37P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.109G>C", "position": 101407795, "grch37Position": 100662783, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a37p" }, { "slug": "a37t", "name": "A37T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.109G>A", "position": 101407795, "grch37Position": 100662783, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/a37t" }, { "slug": "a97v", "name": "A97V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.290C>T", "position": 101403890, "grch37Position": 100658878, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/a97v" }, { "slug": "a121p", "name": "A121P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.361G>C", "position": 101403819, "grch37Position": 100658807, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/a121p" }, { "slug": "a135v", "name": "A135V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.404C>T", "position": 101401775, "grch37Position": 100656763, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/a135v" }, { "slug": "a143p", "name": "A143P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.427G>C", "position": 101401752, "grch37Position": 100656740, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/a143p" }, { "slug": "a156d", "name": "A156D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.467C>A", "position": 101401712, "grch37Position": 100656700, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/a156d" }, { "slug": "a230t", "name": "A230T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.688G>A", "position": 101398898, "grch37Position": 100653886, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/a230t" }, { "slug": "a257v", "name": "A257V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.770C>T", "position": 101398816, "grch37Position": 100653804, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/a257v" }, { "slug": "a285p", "name": "A285P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.853G>C", "position": 101398516, "grch37Position": 100653504, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/a285p" }, { "slug": "a288vfs29", "name": "A288Vfs*29", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.863del", "position": 101398505, "grch37Position": 100653493, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/a288vfs29" }, { "slug": "a291t", "name": "A291T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.871G>A", "position": 101398498, "grch37Position": 100653486, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/a291t" }, { "slug": "a292p", "name": "A292P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.874G>C", "position": 101398495, "grch37Position": 100653483, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/a292p" }, { "slug": "a348gfs27", "name": "A348Gfs*27", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1042dup", "position": 101398056, "grch37Position": 100653044, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/a348gfs27" }, { "slug": "a350p", "name": "A350P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1048G>C", "position": 101398051, "grch37Position": 100653039, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/a350p" }, { "slug": "a352dfs22", "name": "A352Dfs*22", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1055_1056del", "position": 101398042, "grch37Position": 100653030, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/a352dfs22" }, { "slug": "a368lfs25", "name": "A368Lfs*25", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1102delinsTTATAC", "position": 101397997, "grch37Position": 100652985, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/a368lfs25" }, { "slug": "c-1a-g", "name": "c.1A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101407903, "grch37Position": 100662891, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-1a-g" }, { "slug": "c-2t-a", "name": "c.2T>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101407902, "grch37Position": 100662890, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-2t-a" }, { "slug": "c-2t-c", "name": "c.2T>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101407902, "grch37Position": 100662890, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-2t-c" }, { "slug": "c-3g-a", "name": "c.3G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101407901, "grch37Position": 100662889, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-3g-a" }, { "slug": "c-153g-a", "name": "c.153G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101407751, "grch37Position": 100662739, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-153g-a" }, { "slug": "c-194plus1g-a", "name": "c.194+1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101407709, "grch37Position": 100662697, "part": { "kind": "intron", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-194plus1g-a" }, { "slug": "c-194plus1g-t", "name": "c.194+1G>T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101407709, "grch37Position": 100662697, "part": { "kind": "intron", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-194plus1g-t" }, { "slug": "c-195-1g-t", "name": "c.195-1G>T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101403986, "grch37Position": 100658974, "part": { "kind": "intron", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-195-1g-t" }, { "slug": "c-195-2a-g", "name": "c.195-2A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101403987, "grch37Position": 100658975, "part": { "kind": "intron", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c-195-2a-g" }, { "slug": "c-281g-c", "name": "c.281G>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101403899, "grch37Position": 100658887, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c-281g-c" }, { "slug": "c-369plus1g-a", "name": "c.369+1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101403810, "grch37Position": 100658798, "part": { "kind": "intron", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c-369plus1g-a" }, { "slug": "c-370-2a-c", "name": "c.370-2A>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101401811, "grch37Position": 100656799, "part": { "kind": "intron", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c-370-2a-c" }, { "slug": "c-486g-a", "name": "c.486G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101401693, "grch37Position": 100656681, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c-486g-a" }, { "slug": "c-547plus1g-a", "name": "c.547+1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101401631, "grch37Position": 100656619, "part": { "kind": "intron", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c-547plus1g-a" }, { "slug": "c-547plus3a-g", "name": "c.547+3A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101401629, "grch37Position": 100656617, "part": { "kind": "intron", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c-547plus3a-g" }, { "slug": "c-547plus4a-g", "name": "c.547+4A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101401628, "grch37Position": 100656616, "part": { "kind": "intron", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c-547plus4a-g" }, { "slug": "c-548-2a-g", "name": "c.548-2A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101400759, "grch37Position": 100655747, "part": { "kind": "intron", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c-548-2a-g" }, { "slug": "c-639plus1g-a", "name": "c.639+1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101400665, "grch37Position": 100655653, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-639plus1g-a" }, { "slug": "c-639plus2t-c", "name": "c.639+2T>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101400664, "grch37Position": 100655652, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-639plus2t-c" }, { "slug": "c-639plus5g-a", "name": "c.639+5G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101400661, "grch37Position": 100655649, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-639plus5g-a" }, { "slug": "c-640-1g-a", "name": "c.640-1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398947, "grch37Position": 100653935, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-640-1g-a" }, { "slug": "c-640-1g-t", "name": "c.640-1G>T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398947, "grch37Position": 100653935, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-640-1g-t" }, { "slug": "c-640-2a-g", "name": "c.640-2A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398948, "grch37Position": 100653936, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-640-2a-g" }, { "slug": "c-640-801g-a", "name": "c.640-801G>A", "commonName": "IVS4+919G>A", "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101399747, "grch37Position": 100654735, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-640-801g-a" }, { "slug": "c-640-859c-t", "name": "c.640-859C>T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101399805, "grch37Position": 100654793, "part": { "kind": "intron", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c-640-859c-t" }, { "slug": "c-708g-a", "name": "c.708G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398878, "grch37Position": 100653866, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-708g-a" }, { "slug": "c-735g-a", "name": "c.735G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398851, "grch37Position": 100653839, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-735g-a" }, { "slug": "c-782del", "name": "c.782del", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398803, "grch37Position": 100653791, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-782del" }, { "slug": "c-801plus1g-c", "name": "c.801+1G>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101398784, "grch37Position": 100653772, "part": { "kind": "intron", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-801plus1g-c" }, { "slug": "c-801plus3a-g", "name": "c.801+3A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398782, "grch37Position": 100653770, "part": { "kind": "intron", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-801plus3a-g" }, { "slug": "c-802-2a-g", "name": "c.802-2A>G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398569, "grch37Position": 100653557, "part": { "kind": "intron", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-802-2a-g" }, { "slug": "c-802-2a-t", "name": "c.802-2A>T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101398569, "grch37Position": 100653557, "part": { "kind": "intron", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-802-2a-t" }, { "slug": "c-802-3to802-2del", "name": "c.802-3_802-2del", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398568, "grch37Position": 100653556, "part": { "kind": "intron", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c-802-3to802-2del" }, { "slug": "c-870g-c", "name": "c.870G>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101398499, "grch37Position": 100653487, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-870g-c" }, { "slug": "c-966c-a", "name": "c.966C>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398403, "grch37Position": 100653391, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-966c-a" }, { "slug": "c-982g-c", "name": "c.982G>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101398387, "grch37Position": 100653375, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-982g-c" }, { "slug": "c-999plus2t-c", "name": "c.999+2T>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398368, "grch37Position": 100653356, "part": { "kind": "intron", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-999plus2t-c" }, { "slug": "c-1000-1g-a", "name": "c.1000-1G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398100, "grch37Position": 100653088, "part": { "kind": "intron", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-1000-1g-a" }, { "slug": "c-1000-1g-c", "name": "c.1000-1G>C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398100, "grch37Position": 100653088, "part": { "kind": "intron", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-1000-1g-c" }, { "slug": "c-1000-10g-a", "name": "c.1000-10G>A", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101398109, "grch37Position": 100653097, "part": { "kind": "intron", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/c-1000-10g-a" }, { "slug": "c-1019g-a", "name": "c.1019G>A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": null, "position": 101398080, "grch37Position": 100653068, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/c-1019g-a" }, { "slug": "c-1285del", "name": "c.1285del", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": null, "position": 101397813, "grch37Position": 100652801, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/c-1285del" }, { "slug": "c12x", "name": "C12X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.36C>A", "position": 101407868, "grch37Position": 100662856, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c12x" }, { "slug": "c52g", "name": "C52G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.154T>G", "position": 101407750, "grch37Position": 100662738, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c52g" }, { "slug": "c52lfs4", "name": "C52Lfs*4", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.154dup", "position": 101407749, "grch37Position": 100662737, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c52lfs4" }, { "slug": "c52r", "name": "C52R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.154T>C", "position": 101407750, "grch37Position": 100662738, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c52r" }, { "slug": "c52s", "name": "C52S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.155G>C", "position": 101407749, "grch37Position": 100662737, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c52s" }, { "slug": "c52y", "name": "C52Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.155G>A", "position": 101407749, "grch37Position": 100662737, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c52y" }, { "slug": "c56y", "name": "C56Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.167G>A", "position": 101407737, "grch37Position": 100662725, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c56y" }, { "slug": "c63y", "name": "C63Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.188G>A", "position": 101407716, "grch37Position": 100662704, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/c63y" }, { "slug": "c94f", "name": "C94F", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.281G>T", "position": 101403899, "grch37Position": 100658887, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c94f" }, { "slug": "c94s", "name": "C94S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.280T>A", "position": 101403900, "grch37Position": 100658888, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c94s" }, { "slug": "c94y", "name": "C94Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.281G>A", "position": 101403899, "grch37Position": 100658887, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/c94y" }, { "slug": "c142x", "name": "C142X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.426C>A", "position": 101401753, "grch37Position": 100656741, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c142x" }, { "slug": "c172g", "name": "C172G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.514T>G", "position": 101401665, "grch37Position": 100656653, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c172g" }, { "slug": "c172r", "name": "C172R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.514T>C", "position": 101401665, "grch37Position": 100656653, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c172r" }, { "slug": "c172y", "name": "C172Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.515G>A", "position": 101401664, "grch37Position": 100656652, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c172y" }, { "slug": "c174r", "name": "C174R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.520T>C", "position": 101401659, "grch37Position": 100656647, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c174r" }, { "slug": "c174vfs18", "name": "C174Vfs*18", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.520del", "position": 101401658, "grch37Position": 100656646, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/c174vfs18" }, { "slug": "c202r", "name": "C202R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.604T>C", "position": 101400701, "grch37Position": 100655689, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c202r" }, { "slug": "c202w", "name": "C202W", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.606T>G", "position": 101400699, "grch37Position": 100655687, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c202w" }, { "slug": "c202y", "name": "C202Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.605G>A", "position": 101400700, "grch37Position": 100655688, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/c202y" }, { "slug": "c223y", "name": "C223Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.668G>A", "position": 101398918, "grch37Position": 100653906, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/c223y" }, { "slug": "c378r", "name": "C378R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1132T>C", "position": 101397967, "grch37Position": 100652955, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/c378r" }, { "slug": "c378y", "name": "C378Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1133G>A", "position": 101397966, "grch37Position": 100652954, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/c378y" }, { "slug": "d25pfs101", "name": "D25Pfs*101", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.59_72dup", "position": 101407831, "grch37Position": 100662819, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/d25pfs101" }, { "slug": "d92g", "name": "D92G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.275A>G", "position": 101403905, "grch37Position": 100658893, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d92g" }, { "slug": "d92h", "name": "D92H", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.274G>C", "position": 101403906, "grch37Position": 100658894, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d92h" }, { "slug": "d92n", "name": "D92N", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.274G>A", "position": 101403906, "grch37Position": 100658894, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d92n" }, { "slug": "d92v", "name": "D92V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.275A>T", "position": 101403905, "grch37Position": 100658893, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d92v" }, { "slug": "d92y", "name": "D92Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.274G>T", "position": 101403906, "grch37Position": 100658894, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d92y" }, { "slug": "d93g", "name": "D93G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.278A>G", "position": 101403902, "grch37Position": 100658890, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d93g" }, { "slug": "d93n", "name": "D93N", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.277G>A", "position": 101403903, "grch37Position": 100658891, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d93n" }, { "slug": "d93x", "name": "D93X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.273_276dup", "position": 101403903, "grch37Position": 100658891, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d93x" }, { "slug": "d109g", "name": "D109G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.326A>G", "position": 101403854, "grch37Position": 100658842, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/d109g" }, { "slug": "d136y", "name": "D136Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.406G>T", "position": 101401773, "grch37Position": 100656761, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/d136y" }, { "slug": "d155e", "name": "D155E", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.465T>A", "position": 101401714, "grch37Position": 100656702, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/d155e" }, { "slug": "d234del", "name": "D234del", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.700_702del", "position": 101398883, "grch37Position": 100653871, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d234del" }, { "slug": "d234y", "name": "D234Y", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.700G>T", "position": 101398886, "grch37Position": 100653874, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d234y" }, { "slug": "d244h", "name": "D244H", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.730G>C", "position": 101398856, "grch37Position": 100653844, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d244h" }, { "slug": "d244n", "name": "D244N", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.730G>A", "position": 101398856, "grch37Position": 100653844, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d244n" }, { "slug": "d264v", "name": "D264V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.791A>T", "position": 101398795, "grch37Position": 100653783, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d264v" }, { "slug": "d264y", "name": "D264Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.790G>T", "position": 101398796, "grch37Position": 100653784, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d264y" }, { "slug": "d266a", "name": "D266A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.797A>C", "position": 101398789, "grch37Position": 100653777, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d266a" }, { "slug": "d266n", "name": "D266N", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.796G>A", "position": 101398790, "grch37Position": 100653778, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d266n" }, { "slug": "d266v", "name": "D266V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.797A>T", "position": 101398789, "grch37Position": 100653777, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/d266v" }, { "slug": "d322e", "name": "D322E", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.966C>G", "position": 101398403, "grch37Position": 100653391, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/d322e" }, { "slug": "e7nfs114", "name": "E7Nfs*114", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.18del", "position": 101407885, "grch37Position": 100662873, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/e7nfs114" }, { "slug": "e7x", "name": "E7X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.19G>T", "position": 101407885, "grch37Position": 100662873, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/e7x" }, { "slug": "e48x", "name": "E48X", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.142G>T", "position": 101407762, "grch37Position": 100662750, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/e48x" }, { "slug": "e59v", "name": "E59V", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.176A>T", "position": 101407728, "grch37Position": 100662716, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/e59v" }, { "slug": "e66g", "name": "E66G", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.197A>G", "position": 101403983, "grch37Position": 100658971, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/e66g" }, { "slug": "e79x", "name": "E79X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.235G>T", "position": 101403945, "grch37Position": 100658933, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/e79x" }, { "slug": "e103x", "name": "E103X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.307G>T", "position": 101403873, "grch37Position": 100658861, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/e103x" }, { "slug": "e251x", "name": "E251X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.751G>T", "position": 101398835, "grch37Position": 100653823, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/e251x" }, { "slug": "e341dfs7", "name": "E341Dfs*7", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1023del", "position": 101398075, "grch37Position": 100653063, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e341dfs7" }, { "slug": "e341k", "name": "E341K", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1021G>A", "position": 101398078, "grch37Position": 100653066, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e341k" }, { "slug": "e341nfs7", "name": "E341Nfs*7", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1021del", "position": 101398077, "grch37Position": 100653065, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e341nfs7" }, { "slug": "e341x", "name": "E341X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1021G>T", "position": 101398078, "grch37Position": 100653066, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e341x" }, { "slug": "e358del", "name": "E358del", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1072_1074del", "position": 101398024, "grch37Position": 100653012, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e358del" }, { "slug": "e358k", "name": "E358K", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1072G>A", "position": 101398027, "grch37Position": 100653015, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e358k" }, { "slug": "e358x", "name": "E358X", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1072G>T", "position": 101398027, "grch37Position": 100653015, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e358x" }, { "slug": "e398gfs5", "name": "E398Gfs*5", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1193_1196del", "position": 101397902, "grch37Position": 100652890, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e398gfs5" }, { "slug": "e398x", "name": "E398X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1192G>T", "position": 101397907, "grch37Position": 100652895, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/e398x" }, { "slug": "f18s", "name": "F18S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.53T>C", "position": 101407851, "grch37Position": 100662839, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/f18s" }, { "slug": "f50c", "name": "F50C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.149T>G", "position": 101407755, "grch37Position": 100662743, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/f50c" }, { "slug": "f113-r118del", "name": "F113_R118del", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.337_354del", "position": 101403825, "grch37Position": 100658813, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/f113-r118del" }, { "slug": "f113l", "name": "F113L", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.337T>C", "position": 101403843, "grch37Position": 100658831, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/f113l" }, { "slug": "f113s", "name": "F113S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.338T>C", "position": 101403842, "grch37Position": 100658830, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/f113s" }, { "slug": "f229v", "name": "F229V", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.685T>G", "position": 101398901, "grch37Position": 100653889, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/f229v" }, { "slug": "f273s", "name": "F273S", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.818T>C", "position": 101398551, "grch37Position": 100653539, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/f273s" }, { "slug": "f295c", "name": "F295C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.884T>G", "position": 101398485, "grch37Position": 100653473, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/f295c" }, { "slug": "g11afs110", "name": "G11Afs*110", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.32del", "position": 101407871, "grch37Position": 100662859, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/g11afs110" }, { "slug": "g43afs78", "name": "G43Afs*78", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.128del", "position": 101407775, "grch37Position": 100662763, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/g43afs78" }, { "slug": "g43r", "name": "G43R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.127G>C", "position": 101407777, "grch37Position": 100662765, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/g43r" }, { "slug": "g43v", "name": "G43V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.128G>T", "position": 101407776, "grch37Position": 100662764, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/g43v" }, { "slug": "g85d", "name": "G85D", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.254G>A", "position": 101403926, "grch37Position": 100658914, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/g85d" }, { "slug": "g128e", "name": "G128E", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.383G>A", "position": 101401796, "grch37Position": 100656784, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g128e" }, { "slug": "g132r", "name": "G132R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.394G>A", "position": 101401785, "grch37Position": 100656773, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g132r" }, { "slug": "g138e", "name": "G138E", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.413G>A", "position": 101401766, "grch37Position": 100656754, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g138e" }, { "slug": "g138r", "name": "G138R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.412G>A", "position": 101401767, "grch37Position": 100656755, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g138r" }, { "slug": "g144afs21", "name": "G144Afs*21", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.431del", "position": 101401747, "grch37Position": 100656735, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g144afs21" }, { "slug": "g144v", "name": "G144V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.431G>T", "position": 101401748, "grch37Position": 100656736, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g144v" }, { "slug": "g147r", "name": "G147R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.439G>A", "position": 101401740, "grch37Position": 100656728, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g147r" }, { "slug": "g171d", "name": "G171D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.512G>A", "position": 101401667, "grch37Position": 100656655, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g171d" }, { "slug": "g171s", "name": "G171S", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.511G>A", "position": 101401668, "grch37Position": 100656656, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g171s" }, { "slug": "g183d", "name": "G183D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.548G>A", "position": 101400757, "grch37Position": 100655745, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/g183d" }, { "slug": "g183s", "name": "G183S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.547G>A", "position": 101401632, "grch37Position": 100656620, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/g183s" }, { "slug": "g183v", "name": "G183V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.548G>T", "position": 101400757, "grch37Position": 100655745, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/g183v" }, { "slug": "g183vfs9", "name": "G183Vfs*9", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.548del", "position": 101400756, "grch37Position": 100655744, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/g183vfs9" }, { "slug": "g260e", "name": "G260E", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.779G>A", "position": 101398807, "grch37Position": 100653795, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g260e" }, { "slug": "g260r", "name": "G260R", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.778G>A", "position": 101398808, "grch37Position": 100653796, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g260r" }, { "slug": "g261c", "name": "G261C", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.781G>T", "position": 101398805, "grch37Position": 100653793, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g261c" }, { "slug": "g261d", "name": "G261D", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.782G>A", "position": 101398804, "grch37Position": 100653792, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g261d" }, { "slug": "g261v", "name": "G261V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.782G>T", "position": 101398804, "grch37Position": 100653792, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g261v" }, { "slug": "g261vfs8", "name": "G261Vfs*8", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.777del", "position": 101398808, "grch37Position": 100653796, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/g261vfs8" }, { "slug": "g271s", "name": "G271S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.811G>A", "position": 101398558, "grch37Position": 100653546, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g271s" }, { "slug": "g271v", "name": "G271V", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.812G>T", "position": 101398557, "grch37Position": 100653545, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g271v" }, { "slug": "g274r", "name": "G274R", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.820G>C", "position": 101398549, "grch37Position": 100653537, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g274r" }, { "slug": "g325d", "name": "G325D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.974G>A", "position": 101398395, "grch37Position": 100653383, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g325d" }, { "slug": "g328a", "name": "G328A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.983G>C", "position": 101398386, "grch37Position": 100653374, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g328a" }, { "slug": "g328e", "name": "G328E", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.983G>A", "position": 101398386, "grch37Position": 100653374, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g328e" }, { "slug": "g328r", "name": "G328R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.982G>A", "position": 101398387, "grch37Position": 100653375, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/g328r" }, { "slug": "g346afs2", "name": "G346Afs*2", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1037del", "position": 101398061, "grch37Position": 100653049, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g346afs2" }, { "slug": "g360d", "name": "G360D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1079G>A", "position": 101398020, "grch37Position": 100653008, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g360d" }, { "slug": "g360r", "name": "G360R", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1078G>C", "position": 101398021, "grch37Position": 100653009, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g360r" }, { "slug": "g361r", "name": "G361R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1081G>A", "position": 101398018, "grch37Position": 100653006, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g361r" }, { "slug": "g373d", "name": "G373D", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1118G>A", "position": 101397981, "grch37Position": 100652969, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g373d" }, { "slug": "g373s", "name": "G373S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1117G>A", "position": 101397982, "grch37Position": 100652970, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g373s" }, { "slug": "g411d", "name": "G411D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1232G>A", "position": 101397867, "grch37Position": 100652855, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/g411d" }, { "slug": "h9lfs112", "name": "H9Lfs*112", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.26del", "position": 101407877, "grch37Position": 100662865, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/h9lfs112" }, { "slug": "h46p", "name": "H46P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.137A>C", "position": 101407767, "grch37Position": 100662755, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/h46p" }, { "slug": "h46y", "name": "H46Y", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.136C>T", "position": 101407768, "grch37Position": 100662756, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/h46y" }, { "slug": "h125l", "name": "H125L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.374A>T", "position": 101401805, "grch37Position": 100656793, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/h125l" }, { "slug": "h225d", "name": "H225D", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.673C>G", "position": 101398913, "grch37Position": 100653901, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/h225d" }, { "slug": "h225r", "name": "H225R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.674A>G", "position": 101398912, "grch37Position": 100653900, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/h225r" }, { "slug": "h302tfs13", "name": "H302Tfs*13", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.902dup", "position": 101398466, "grch37Position": 100653454, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/h302tfs13" }, { "slug": "i91t", "name": "I91T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.272T>C", "position": 101403908, "grch37Position": 100658896, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/i91t" }, { "slug": "i117s", "name": "I117S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.350T>G", "position": 101403830, "grch37Position": 100658818, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/i117s" }, { "slug": "i219t", "name": "I219T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.656T>C", "position": 101398930, "grch37Position": 100653918, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/i219t" }, { "slug": "i232t", "name": "I232T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.695T>C", "position": 101398891, "grch37Position": 100653879, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/i232t" }, { "slug": "i242yfs8", "name": "I242Yfs*8", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.723dup", "position": 101398862, "grch37Position": 100653850, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/i242yfs8" }, { "slug": "i253t", "name": "I253T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.758T>C", "position": 101398828, "grch37Position": 100653816, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/i253t" }, { "slug": "i270t", "name": "I270T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.809T>C", "position": 101398560, "grch37Position": 100653548, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/i270t" }, { "slug": "i303n", "name": "I303N", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.908T>A", "position": 101398461, "grch37Position": 100653449, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/i303n" }, { "slug": "i317nfs16", "name": "I317Nfs*16", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.947dup", "position": 101398421, "grch37Position": 100653409, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/i317nfs16" }, { "slug": "i317t", "name": "I317T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.950T>C", "position": 101398419, "grch37Position": 100653407, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/i317t" }, { "slug": "i319lfs31", "name": "I319Lfs*31", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.950_954dup", "position": 101398414, "grch37Position": 100653402, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/i319lfs31" }, { "slug": "i354k", "name": "I354K", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1061T>A", "position": 101398038, "grch37Position": 100653026, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/i354k" }, { "slug": "k127x", "name": "K127X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.379A>T", "position": 101401800, "grch37Position": 100656788, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/k127x" }, { "slug": "k185x", "name": "K185X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.553A>T", "position": 101400752, "grch37Position": 100655740, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/k185x" }, { "slug": "k240efs9", "name": "K240Efs*9", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.718_719del", "position": 101398866, "grch37Position": 100653854, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/k240efs9" }, { "slug": "k308n", "name": "K308N", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.924A>C", "position": 101398445, "grch37Position": 100653433, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/k308n" }, { "slug": "l14p", "name": "L14P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.41T>C", "position": 101407863, "grch37Position": 100662851, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/l14p" }, { "slug": "l16ffs105", "name": "L16Ffs*105", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.45del", "position": 101407858, "grch37Position": 100662846, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/l16ffs105" }, { "slug": "l16p", "name": "L16P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.47T>C", "position": 101407857, "grch37Position": 100662845, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/l16p" }, { "slug": "l21p", "name": "L21P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.62T>C", "position": 101407842, "grch37Position": 100662830, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/l21p" }, { "slug": "l32p", "name": "L32P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.95T>C", "position": 101407809, "grch37Position": 100662797, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/l32p" }, { "slug": "l68f", "name": "L68F", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.202C>T", "position": 101403978, "grch37Position": 100658966, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/l68f" }, { "slug": "l89h", "name": "L89H", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.266T>A", "position": 101403914, "grch37Position": 100658902, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/l89h" }, { "slug": "l89p", "name": "L89P", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.266T>C", "position": 101403914, "grch37Position": 100658902, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/l89p" }, { "slug": "l89r", "name": "L89R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.266T>G", "position": 101403914, "grch37Position": 100658902, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/l89r" }, { "slug": "l106f", "name": "L106F", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.316C>T", "position": 101403864, "grch37Position": 100658852, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/l106f" }, { "slug": "l129p", "name": "L129P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.386T>C", "position": 101401793, "grch37Position": 100656781, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/l129p" }, { "slug": "l167p", "name": "L167P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.500T>C", "position": 101401679, "grch37Position": 100656667, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/l167p" }, { "slug": "l180f", "name": "L180F", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.540G>C", "position": 101401639, "grch37Position": 100656627, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/l180f" }, { "slug": "l189wfs3", "name": "L189Wfs*3", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.564del", "position": 101400740, "grch37Position": 100655728, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/l189wfs3" }, { "slug": "l268x", "name": "L268X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.803_806del", "position": 101398562, "grch37Position": 100653550, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/l268x" }, { "slug": "l275qfs23", "name": "L275Qfs*23", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.824_825del", "position": 101398543, "grch37Position": 100653531, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/l275qfs23" }, { "slug": "l300p", "name": "L300P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.899T>C", "position": 101398470, "grch37Position": 100653458, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/l300p" }, { "slug": "l311f", "name": "L311F", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.931C>T", "position": 101398438, "grch37Position": 100653426, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/l311f" }, { "slug": "l324wfs24", "name": "L324Wfs*24", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.969del", "position": 101398399, "grch37Position": 100653387, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/l324wfs24" }, { "slug": "l415p", "name": "L415P", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1244T>C", "position": 101397855, "grch37Position": 100652843, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/l415p" }, { "slug": "m42i", "name": "M42I", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.126G>C", "position": 101407778, "grch37Position": 100662766, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/m42i" }, { "slug": "m42l", "name": "M42L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.124A>C", "position": 101407780, "grch37Position": 100662768, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/m42l" }, { "slug": "m42t", "name": "M42T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.125T>C", "position": 101407779, "grch37Position": 100662767, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/m42t" }, { "slug": "m42v", "name": "M42V", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.124A>G", "position": 101407780, "grch37Position": 100662768, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/m42v" }, { "slug": "m51i", "name": "M51I", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.153G>T", "position": 101407751, "grch37Position": 100662739, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/m51i" }, { "slug": "m187t", "name": "M187T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.560T>C", "position": 101400745, "grch37Position": 100655733, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/m187t" }, { "slug": "m187v", "name": "M187V", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.559A>G", "position": 101400746, "grch37Position": 100655734, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/m187v" }, { "slug": "m187vfs6", "name": "M187Vfs*6", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.559_560del", "position": 101400744, "grch37Position": 100655732, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/m187vfs6" }, { "slug": "m267i", "name": "M267I", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.801G>A", "position": 101398785, "grch37Position": 100653773, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/m267i" }, { "slug": "m267r", "name": "M267R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.800T>G", "position": 101398786, "grch37Position": 100653774, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/m267r" }, { "slug": "m284dfs15", "name": "M284Dfs*15", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.848dup", "position": 101398520, "grch37Position": 100653508, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m284dfs15" }, { "slug": "m284t", "name": "M284T", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.851T>C", "position": 101398518, "grch37Position": 100653506, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m284t" }, { "slug": "m290i", "name": "M290I", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.870G>A", "position": 101398499, "grch37Position": 100653487, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m290i" }, { "slug": "m290l", "name": "M290L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.868A>C", "position": 101398501, "grch37Position": 100653489, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m290l" }, { "slug": "m290t", "name": "M290T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.869T>C", "position": 101398500, "grch37Position": 100653488, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m290t" }, { "slug": "m296i", "name": "M296I", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.888G>T", "position": 101398481, "grch37Position": 100653469, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m296i" }, { "slug": "m296l", "name": "M296L", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.886A>T", "position": 101398483, "grch37Position": 100653471, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m296l" }, { "slug": "m296t", "name": "M296T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.887T>C", "position": 101398482, "grch37Position": 100653470, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m296t" }, { "slug": "m296v", "name": "M296V", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.886A>G", "position": 101398483, "grch37Position": 100653471, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/m296v" }, { "slug": "m353dfs21", "name": "M353Dfs*21", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1057_1058del", "position": 101398040, "grch37Position": 100653028, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/m353dfs21" }, { "slug": "n34s", "name": "N34S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.101A>G", "position": 101407803, "grch37Position": 100662791, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/n34s" }, { "slug": "n139kfs2", "name": "N139Kfs*2", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.413dup", "position": 101401765, "grch37Position": 100656753, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/n139kfs2" }, { "slug": "n215s", "name": "N215S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.644A>G", "position": 101398942, "grch37Position": 100653930, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/n215s" }, { "slug": "n224s", "name": "N224S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.671A>G", "position": 101398915, "grch37Position": 100653903, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/n224s" }, { "slug": "n272s", "name": "N272S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.815A>G", "position": 101398554, "grch37Position": 100653542, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/n272s" }, { "slug": "n278kfs21", "name": "N278Kfs*21", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.833dup", "position": 101398535, "grch37Position": 100653523, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/n278kfs21" }, { "slug": "n298k", "name": "N298K", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.894T>A", "position": 101398475, "grch37Position": 100653463, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/n298k" }, { "slug": "n320rfs27", "name": "N320Rfs*27", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.959_962del", "position": 101398406, "grch37Position": 100653394, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/n320rfs27" }, { "slug": "n355-i359del", "name": "N355_I359del", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1062_1076del", "position": 101398022, "grch37Position": 100653010, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/n355-i359del" }, { "slug": "n355kfs20", "name": "N355Kfs*20", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1064dup", "position": 101398034, "grch37Position": 100653022, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/n355kfs20" }, { "slug": "p40l", "name": "P40L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.119C>T", "position": 101407785, "grch37Position": 100662773, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/p40l" }, { "slug": "p40s", "name": "P40S", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.118C>T", "position": 101407786, "grch37Position": 100662774, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/p40s" }, { "slug": "p205-y207del", "name": "P205_Y207del", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.613_621del", "position": 101400683, "grch37Position": 100655671, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/p205-y207del" }, { "slug": "p205l", "name": "P205L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.614C>T", "position": 101400691, "grch37Position": 100655679, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/p205l" }, { "slug": "p205s", "name": "P205S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.613C>T", "position": 101400692, "grch37Position": 100655680, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/p205s" }, { "slug": "p205t", "name": "P205T", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.613C>A", "position": 101400692, "grch37Position": 100655680, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/p205t" }, { "slug": "p214l", "name": "P214L", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.641C>T", "position": 101398945, "grch37Position": 100653933, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/p214l" }, { "slug": "p259r", "name": "P259R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.776C>G", "position": 101398810, "grch37Position": 100653798, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/p259r" }, { "slug": "p293l", "name": "P293L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.878C>T", "position": 101398491, "grch37Position": 100653479, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/p293l" }, { "slug": "p362l", "name": "P362L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1085C>T", "position": 101398014, "grch37Position": 100653002, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p362l" }, { "slug": "p380lfs11", "name": "P380Lfs*11", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1139del", "position": 101397959, "grch37Position": 100652947, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p380lfs11" }, { "slug": "p389a", "name": "P389A", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1165C>G", "position": 101397934, "grch37Position": 100652922, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p389a" }, { "slug": "p409a", "name": "P409A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1225C>G", "position": 101397874, "grch37Position": 100652862, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p409a" }, { "slug": "p409s", "name": "P409S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1225C>T", "position": 101397874, "grch37Position": 100652862, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p409s" }, { "slug": "p409t", "name": "P409T", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1225C>A", "position": 101397874, "grch37Position": 100652862, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/p409t" }, { "slug": "q2x", "name": "Q2X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.4C>T", "position": 101407900, "grch37Position": 100662888, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/q2x" }, { "slug": "q57x", "name": "Q57X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.169C>T", "position": 101407735, "grch37Position": 100662723, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/q57x" }, { "slug": "q99kfs22", "name": "Q99Kfs*22", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.295del", "position": 101403884, "grch37Position": 100658872, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/q99kfs22" }, { "slug": "q99x", "name": "Q99X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.295C>T", "position": 101403885, "grch37Position": 100658873, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/q99x" }, { "slug": "q119x", "name": "Q119X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.355C>T", "position": 101403825, "grch37Position": 100658813, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/q119x" }, { "slug": "q157x", "name": "Q157X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.469C>T", "position": 101401710, "grch37Position": 100656698, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/q157x" }, { "slug": "q221x", "name": "Q221X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.661C>T", "position": 101398925, "grch37Position": 100653913, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/q221x" }, { "slug": "q250p", "name": "Q250P", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.749A>C", "position": 101398837, "grch37Position": 100653825, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/q250p" }, { "slug": "q250x", "name": "Q250X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.748C>T", "position": 101398838, "grch37Position": 100653826, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/q250x" }, { "slug": "q279e", "name": "Q279E", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.835C>G", "position": 101398534, "grch37Position": 100653522, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q279e" }, { "slug": "q279r", "name": "Q279R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.836A>G", "position": 101398533, "grch37Position": 100653521, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q279r" }, { "slug": "q279x", "name": "Q279X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.835C>T", "position": 101398534, "grch37Position": 100653522, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q279x" }, { "slug": "q280x", "name": "Q280X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.838C>T", "position": 101398531, "grch37Position": 100653519, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q280x" }, { "slug": "q283x", "name": "Q283X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.847C>T", "position": 101398522, "grch37Position": 100653510, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q283x" }, { "slug": "q306x", "name": "Q306X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.916C>T", "position": 101398453, "grch37Position": 100653441, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q306x" }, { "slug": "q312h", "name": "Q312H", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.936G>C", "position": 101398433, "grch37Position": 100653421, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q312h" }, { "slug": "q321e", "name": "Q321E", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.961C>G", "position": 101398408, "grch37Position": 100653396, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q321e" }, { "slug": "q321r", "name": "Q321R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.962A>G", "position": 101398407, "grch37Position": 100653395, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q321r" }, { "slug": "q327x", "name": "Q327X", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.979C>T", "position": 101398390, "grch37Position": 100653378, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q327x" }, { "slug": "q330sfs18", "name": "Q330Sfs*18", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.988del", "position": 101398380, "grch37Position": 100653368, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q330sfs18" }, { "slug": "q333efs14", "name": "Q333Efs*14", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.996_999del", "position": 101398369, "grch37Position": 100653357, "part": { "kind": "intron", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/q333efs14" }, { "slug": "q386p", "name": "Q386P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1157A>C", "position": 101397942, "grch37Position": 100652930, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/q386p" }, { "slug": "q386x", "name": "Q386X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1156C>T", "position": 101397943, "grch37Position": 100652931, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/q386x" }, { "slug": "r17pfs12", "name": "R17Pfs*12", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.50_54del", "position": 101407849, "grch37Position": 100662837, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/r17pfs12" }, { "slug": "r49g", "name": "R49G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.145C>G", "position": 101407759, "grch37Position": 100662747, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/r49g" }, { "slug": "r49p", "name": "R49P", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.146G>C", "position": 101407758, "grch37Position": 100662746, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/r49p" }, { "slug": "r100x", "name": "R100X", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.298A>T", "position": 101403882, "grch37Position": 100658870, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/r100x" }, { "slug": "r112c", "name": "R112C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.334C>T", "position": 101403846, "grch37Position": 100658834, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/r112c" }, { "slug": "r112h", "name": "R112H", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.335G>A", "position": 101403845, "grch37Position": 100658833, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/r112h" }, { "slug": "r112l", "name": "R112L", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.335G>T", "position": 101403845, "grch37Position": 100658833, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/r112l" }, { "slug": "r220x", "name": "R220X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.658C>T", "position": 101398928, "grch37Position": 100653916, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/r220x" }, { "slug": "r227q", "name": "R227Q", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.680G>A", "position": 101398906, "grch37Position": 100653894, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/r227q" }, { "slug": "r227x", "name": "R227X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.679C>T", "position": 101398907, "grch37Position": 100653895, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/r227x" }, { "slug": "r301g", "name": "R301G", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.901C>G", "position": 101398468, "grch37Position": 100653456, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r301g" }, { "slug": "r301p", "name": "R301P", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.902G>C", "position": 101398467, "grch37Position": 100653455, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r301p" }, { "slug": "r301q", "name": "R301Q", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.902G>A", "position": 101398467, "grch37Position": 100653455, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r301q" }, { "slug": "r301x", "name": "R301X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.901C>T", "position": 101398468, "grch37Position": 100653456, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r301x" }, { "slug": "r332kfs7", "name": "R332Kfs*7", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.994dup", "position": 101398374, "grch37Position": 100653362, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r332kfs7" }, { "slug": "r332tfs6", "name": "R332Tfs*6", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.993_994del", "position": 101398374, "grch37Position": 100653362, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/r332tfs6" }, { "slug": "r342q", "name": "R342Q", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1025G>A", "position": 101398074, "grch37Position": 100653062, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r342q" }, { "slug": "r342x", "name": "R342X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1024C>T", "position": 101398075, "grch37Position": 100653063, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r342x" }, { "slug": "r356g", "name": "R356G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1066C>G", "position": 101398033, "grch37Position": 100653021, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r356g" }, { "slug": "r356w", "name": "R356W", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1066C>T", "position": 101398033, "grch37Position": 100653021, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r356w" }, { "slug": "r363c", "name": "R363C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1087C>T", "position": 101398012, "grch37Position": 100653000, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r363c" }, { "slug": "r363h", "name": "R363H", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1088G>A", "position": 101398011, "grch37Position": 100652999, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r363h" }, { "slug": "r404del", "name": "R404del", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1212_1214del", "position": 101397884, "grch37Position": 100652872, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/r404del" }, { "slug": "s102qfs19", "name": "S102Qfs*19", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.304del", "position": 101403875, "grch37Position": 100658863, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/s102qfs19" }, { "slug": "s148n", "name": "S148N", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.443G>A", "position": 101401736, "grch37Position": 100656724, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/s148n" }, { "slug": "s148r", "name": "S148R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.444T>G", "position": 101401735, "grch37Position": 100656723, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/s148r" }, { "slug": "s235c", "name": "S235C", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.704C>G", "position": 101398882, "grch37Position": 100653870, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/s235c" }, { "slug": "s238n", "name": "S238N", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.713G>A", "position": 101398873, "grch37Position": 100653861, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/s238n" }, { "slug": "s276g", "name": "S276G", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.826A>G", "position": 101398543, "grch37Position": 100653531, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s276g" }, { "slug": "s276n", "name": "S276N", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.827G>A", "position": 101398542, "grch37Position": 100653530, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s276n" }, { "slug": "s276r", "name": "S276R", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.828C>A", "position": 101398541, "grch37Position": 100653529, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s276r" }, { "slug": "s297f", "name": "S297F", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.890C>T", "position": 101398479, "grch37Position": 100653467, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s297f" }, { "slug": "s297p", "name": "S297P", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.889T>C", "position": 101398480, "grch37Position": 100653468, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s297p" }, { "slug": "s297y", "name": "S297Y", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.890C>A", "position": 101398479, "grch37Position": 100653467, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/s297y" }, { "slug": "s345rfs29", "name": "S345Rfs*29", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1033_1034del", "position": 101398064, "grch37Position": 100653052, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/s345rfs29" }, { "slug": "s401ffs33", "name": "S401Ffs*33", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1201dup", "position": 101397897, "grch37Position": 100652885, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/s401ffs33" }, { "slug": "t141i", "name": "T141I", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.422C>T", "position": 101401757, "grch37Position": 100656745, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/t141i" }, { "slug": "t410a", "name": "T410A", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1228A>G", "position": 101397871, "grch37Position": 100652859, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/t410a" }, { "slug": "t410k", "name": "T410K", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1229C>A", "position": 101397870, "grch37Position": 100652858, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/t410k" }, { "slug": "t412sfs21", "name": "T412Sfs*21", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1235_1236del", "position": 101397862, "grch37Position": 100652850, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/t412sfs21" }, { "slug": "v269m", "name": "V269M", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.805G>A", "position": 101398564, "grch37Position": 100653552, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/v269m" }, { "slug": "v376pfs10", "name": "V376Pfs*10", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1125_1140del", "position": 101397958, "grch37Position": 100652946, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/v376pfs10" }, { "slug": "v390m", "name": "V390M", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.1168G>A", "position": 101397931, "grch37Position": 100652919, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/v390m" }, { "slug": "w47r", "name": "W47R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.139T>C", "position": 101407765, "grch37Position": 100662753, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/w47r" }, { "slug": "w47x", "name": "W47X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.141G>A", "position": 101407763, "grch37Position": 100662751, "part": { "kind": "exon", "number": 1 }, "url": "https://dantelabs.com/genes/gla/variants/w47x" }, { "slug": "w81s", "name": "W81S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.242G>C", "position": 101403938, "grch37Position": 100658926, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/w81s" }, { "slug": "w81x", "name": "W81X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.242G>A", "position": 101403938, "grch37Position": 100658926, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/w81x" }, { "slug": "w95c", "name": "W95C", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.285G>T", "position": 101403895, "grch37Position": 100658883, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/w95c" }, { "slug": "w95l", "name": "W95L", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.284G>T", "position": 101403896, "grch37Position": 100658884, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/w95l" }, { "slug": "w162gfs3", "name": "W162Gfs*3", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.484del", "position": 101401694, "grch37Position": 100656682, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/w162gfs3" }, { "slug": "w162r", "name": "W162R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.484T>C", "position": 101401695, "grch37Position": 100656683, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/w162r" }, { "slug": "w162x", "name": "W162X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.485G>A", "position": 101401694, "grch37Position": 100656682, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/w162x" }, { "slug": "w204r", "name": "W204R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.610T>C", "position": 101400695, "grch37Position": 100655683, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/w204r" }, { "slug": "w204x", "name": "W204X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.611G>A", "position": 101400694, "grch37Position": 100655682, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/w204x" }, { "slug": "w209x", "name": "W209X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.627G>A", "position": 101400678, "grch37Position": 100655666, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/w209x" }, { "slug": "w226x", "name": "W226X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.677G>A", "position": 101398909, "grch37Position": 100653897, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/w226x" }, { "slug": "w236r", "name": "W236R", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.706T>C", "position": 101398880, "grch37Position": 100653868, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/w236r" }, { "slug": "w236x", "name": "W236X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.707G>A", "position": 101398879, "grch37Position": 100653867, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/w236x" }, { "slug": "w245x", "name": "W245X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.734G>A", "position": 101398852, "grch37Position": 100653840, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/w245x" }, { "slug": "w277x", "name": "W277X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.830G>A", "position": 101398539, "grch37Position": 100653527, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/w277x" }, { "slug": "w287c", "name": "W287C", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.861G>T", "position": 101398508, "grch37Position": 100653496, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/w287c" }, { "slug": "w287x", "name": "W287X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.860G>A", "position": 101398509, "grch37Position": 100653497, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/w287x" }, { "slug": "w340r", "name": "W340R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1018T>C", "position": 101398081, "grch37Position": 100653069, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/w340r" }, { "slug": "w340x", "name": "W340X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1020G>A", "position": 101398079, "grch37Position": 100653067, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/w340x" }, { "slug": "w349r", "name": "W349R", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1045T>C", "position": 101398054, "grch37Position": 100653042, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/w349r" }, { "slug": "w349x", "name": "W349X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1046G>A", "position": 101398053, "grch37Position": 100653041, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/w349x" }, { "slug": "w399x", "name": "W399X", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.1197G>A", "position": 101397902, "grch37Position": 100652890, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/w399x" }, { "slug": "y86d", "name": "Y86D", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.256T>G", "position": 101403924, "grch37Position": 100658912, "part": { "kind": "exon", "number": 2 }, "url": "https://dantelabs.com/genes/gla/variants/y86d" }, { "slug": "y134h", "name": "Y134H", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.400T>C", "position": 101401779, "grch37Position": 100656767, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/y134h" }, { "slug": "y134x", "name": "Y134X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.402T>G", "position": 101401777, "grch37Position": 100656765, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/y134x" }, { "slug": "y151x", "name": "Y151X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.453C>G", "position": 101401726, "grch37Position": 100656714, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/y151x" }, { "slug": "y152x", "name": "Y152X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.456C>A", "position": 101401723, "grch37Position": 100656711, "part": { "kind": "exon", "number": 3 }, "url": "https://dantelabs.com/genes/gla/variants/y152x" }, { "slug": "y184d", "name": "Y184D", "commonName": null, "symbol": "GLA", "classification": "likely-pathogenic", "stars": 2, "hgvsC": "c.550T>G", "position": 101400755, "grch37Position": 100655743, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/y184d" }, { "slug": "y207s", "name": "Y207S", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.620A>C", "position": 101400685, "grch37Position": 100655673, "part": { "kind": "exon", "number": 4 }, "url": "https://dantelabs.com/genes/gla/variants/y207s" }, { "slug": "y216c", "name": "Y216C", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.647A>G", "position": 101398939, "grch37Position": 100653927, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/y216c" }, { "slug": "y216d", "name": "Y216D", "commonName": null, "symbol": "GLA", "classification": "pathogenic-likely-pathogenic", "stars": 2, "hgvsC": "c.646T>G", "position": 101398940, "grch37Position": 100653928, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/y216d" }, { "slug": "y216lfs16", "name": "Y216Lfs*16", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.646dup", "position": 101398939, "grch37Position": 100653927, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/y216lfs16" }, { "slug": "y222x", "name": "Y222X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.666C>A", "position": 101398920, "grch37Position": 100653908, "part": { "kind": "exon", "number": 5 }, "url": "https://dantelabs.com/genes/gla/variants/y222x" }, { "slug": "y329tfs19", "name": "Y329Tfs*19", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.984del", "position": 101398384, "grch37Position": 100653372, "part": { "kind": "exon", "number": 6 }, "url": "https://dantelabs.com/genes/gla/variants/y329tfs19" }, { "slug": "y365x", "name": "Y365X", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1094dup", "position": 101398004, "grch37Position": 100652992, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/y365x" }, { "slug": "y397mfs7", "name": "Y397Mfs*7", "commonName": null, "symbol": "GLA", "classification": "pathogenic", "stars": 2, "hgvsC": "c.1188del", "position": 101397910, "grch37Position": 100652898, "part": { "kind": "exon", "number": 7 }, "url": "https://dantelabs.com/genes/gla/variants/y397mfs7" } ] } }