{
  "url": "https://dantelabs.com/de/genes/fbxl3",
  "gene": {
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    "symbol": "FBXL3",
    "name": "F-box and leucine rich repeat protein 3",
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      "ensemblTranscript": "ENST00000355619.10",
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        {
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        {
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      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
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        "name": "Abnormally small head",
        "systems": [
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        "url": "https://dantelabs.com/traits/microcephaly"
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      {
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        "systems": [
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      },
      {
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/bulbous-nose"
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        "url": "https://dantelabs.com/traits/strabismus"
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      {
        "slug": "delayed-speech-and-language-development",
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/delayed-speech-and-language-development"
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      {
        "slug": "dysarthria",
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        "url": "https://dantelabs.com/traits/dysarthria"
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      {
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        "name": "Double-Jointed",
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/joint-hypermobility"
      },
      {
        "slug": "ptosis",
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ptosis"
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      {
        "slug": "global-developmental-delay",
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
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      {
        "slug": "high-palate",
        "name": "High palate",
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/high-palate"
      },
      {
        "slug": "intellectual-disability",
        "name": "Intellectual disability",
        "systems": [
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/intellectual-disability"
      },
      {
        "slug": "joint-dislocation",
        "name": "Joint dislocation",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/joint-dislocation"
      },
      {
        "slug": "poor-speech",
        "name": "Poor speech",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "url": "https://dantelabs.com/traits/poor-speech"
      },
      {
        "slug": "prominent-nose",
        "name": "Prominent nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/prominent-nose"
      },
      {
        "slug": "short-clavicles",
        "name": "Short collarbone",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-clavicles"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "short-4th-metacarpal",
        "name": "Shortened 4th long bone of hand",
        "systems": [
          "abnormality-of-limbs",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-4th-metacarpal"
      },
      {
        "slug": "sleep-wake-cycle-disturbance",
        "name": "Sleep-wake cycle disturbance",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/sleep-wake-cycle-disturbance"
      },
      {
        "slug": "microretrognathia",
        "name": "Small retruded chin",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/microretrognathia"
      },
      {
        "slug": "wide-nasal-bridge",
        "name": "Wide nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/wide-nasal-bridge"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}