{
  "url": "https://dantelabs.com/traits/splenic-rupture",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "splenic-rupture",
    "id": "HP:0012223",
    "name": "Splenic rupture",
    "definition": "A breach of the capsule of the spleen.",
    "synonyms": [
      "Ruptured spleen"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-spleen-morphology",
        "name": "Abnormal spleen morphology",
        "url": "https://dantelabs.com/traits/abnormal-spleen-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "col3a1",
        "symbol": "COL3A1",
        "hgnc": "HGNC:2201",
        "name": "collagen type III alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col3a1"
      },
      {
        "slug": "fga",
        "symbol": "FGA",
        "hgnc": "HGNC:3661",
        "name": "fibrinogen alpha chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fga"
      },
      {
        "slug": "fgb",
        "symbol": "FGB",
        "hgnc": "HGNC:3662",
        "name": "fibrinogen beta chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgb"
      },
      {
        "slug": "fgg",
        "symbol": "FGG",
        "hgnc": "HGNC:3694",
        "name": "fibrinogen gamma chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgg"
      },
      {
        "slug": "gba1",
        "symbol": "GBA1",
        "hgnc": "HGNC:4177",
        "name": "glucosylceramidase beta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gba1"
      },
      {
        "slug": "scarb2",
        "symbol": "SCARB2",
        "hgnc": "HGNC:1665",
        "name": "scavenger receptor class B member 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scarb2"
      }
    ]
  }
}