{
  "url": "https://dantelabs.com/traits/retinal-degeneration",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "retinal-degeneration",
    "id": "HP:0000546",
    "name": "Retina degeneration",
    "label": "Retinal degeneration",
    "definition": "A nonspecific term denoting progressive loss of the retinal pigment epithelium (RPE) and/or neurosensory retinal cells.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-retinal-morphology",
        "name": "Retina issue",
        "url": "https://dantelabs.com/traits/abnormal-retinal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "retinal-atrophy",
        "name": "Retinal atrophy",
        "genes": 145,
        "url": "https://dantelabs.com/traits/retinal-atrophy"
      },
      {
        "slug": "macular-degeneration",
        "name": "Macular degeneration",
        "genes": 68,
        "url": "https://dantelabs.com/traits/macular-degeneration"
      },
      {
        "slug": "peripheral-retinal-degeneration",
        "name": "Peripheral retinal degeneration",
        "genes": 0,
        "url": "https://dantelabs.com/traits/peripheral-retinal-degeneration"
      }
    ],
    "genes": [
      {
        "slug": "arl6",
        "symbol": "ARL6",
        "hgnc": "HGNC:13210",
        "name": "ARF like GTPase 6",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/arl6"
      },
      {
        "slug": "arsg",
        "symbol": "ARSG",
        "hgnc": "HGNC:24102",
        "name": "arylsulfatase G",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arsg"
      },
      {
        "slug": "bbs1",
        "symbol": "BBS1",
        "hgnc": "HGNC:966",
        "name": "Bardet-Biedl syndrome 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs1"
      },
      {
        "slug": "bbs9",
        "symbol": "BBS9",
        "hgnc": "HGNC:30000",
        "name": "Bardet-Biedl syndrome 9",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs9"
      },
      {
        "slug": "ccdc28b",
        "symbol": "CCDC28B",
        "hgnc": "HGNC:28163",
        "name": "coiled-coil domain containing 28B",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc28b"
      },
      {
        "slug": "cln3",
        "symbol": "CLN3",
        "hgnc": "HGNC:2074",
        "name": "CLN3 lysosomal/endosomal transmembrane protein, battenin",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cln3"
      },
      {
        "slug": "fdxr",
        "symbol": "FDXR",
        "hgnc": "HGNC:3642",
        "name": "ferredoxin reductase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fdxr"
      },
      {
        "slug": "lztfl1",
        "symbol": "LZTFL1",
        "hgnc": "HGNC:6741",
        "name": "leucine zipper transcription factor like 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lztfl1"
      },
      {
        "slug": "nmnat1",
        "symbol": "NMNAT1",
        "hgnc": "HGNC:17877",
        "name": "nicotinamide nucleotide adenylyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nmnat1"
      },
      {
        "slug": "nrl",
        "symbol": "NRL",
        "hgnc": "HGNC:8002",
        "name": "neural retina leucine zipper",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nrl"
      },
      {
        "slug": "pnpla6",
        "symbol": "PNPLA6",
        "hgnc": "HGNC:16268",
        "name": "patatin like domain 6, lysophospholipase",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pnpla6"
      },
      {
        "slug": "pomk",
        "symbol": "POMK",
        "hgnc": "HGNC:26267",
        "name": "protein O-mannose kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomk"
      },
      {
        "slug": "prpf4",
        "symbol": "PRPF4",
        "hgnc": "HGNC:17349",
        "name": "pre-mRNA splicing tri-snRNP complex factor PRPF4",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prpf4"
      },
      {
        "slug": "ubap1l",
        "symbol": "UBAP1L",
        "hgnc": "HGNC:40028",
        "name": "ubiquitin associated protein 1 like",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap1l"
      },
      {
        "slug": "abca4",
        "symbol": "ABCA4",
        "hgnc": "HGNC:34",
        "name": "ATP binding cassette subfamily A member 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/abca4"
      },
      {
        "slug": "agbl5",
        "symbol": "AGBL5",
        "hgnc": "HGNC:26147",
        "name": "AGBL carboxypeptidase 5",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agbl5"
      },
      {
        "slug": "ahi1",
        "symbol": "AHI1",
        "hgnc": "HGNC:21575",
        "name": "Abelson helper integration site 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahi1"
      },
      {
        "slug": "ahr",
        "symbol": "AHR",
        "hgnc": "HGNC:348",
        "name": "aryl hydrocarbon receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahr"
      },
      {
        "slug": "arhgef18",
        "symbol": "ARHGEF18",
        "hgnc": "HGNC:17090",
        "name": "Rho/Rac guanine nucleotide exchange factor 18",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arhgef18"
      },
      {
        "slug": "arl2bp",
        "symbol": "ARL2BP",
        "hgnc": "HGNC:17146",
        "name": "ARF like GTPase 2 binding protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl2bp"
      },
      {
        "slug": "arl3",
        "symbol": "ARL3",
        "hgnc": "HGNC:694",
        "name": "ARF like GTPase 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl3"
      },
      {
        "slug": "bbs2",
        "symbol": "BBS2",
        "hgnc": "HGNC:967",
        "name": "Bardet-Biedl syndrome 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bbs2"
      },
      {
        "slug": "best1",
        "symbol": "BEST1",
        "hgnc": "HGNC:12703",
        "name": "bestrophin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/best1"
      },
      {
        "slug": "ca4",
        "symbol": "CA4",
        "hgnc": "HGNC:1375",
        "name": "carbonic anhydrase 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ca4"
      },
      {
        "slug": "cc2d2a",
        "symbol": "CC2D2A",
        "hgnc": "HGNC:29253",
        "name": "coiled-coil and C2 domain containing 2A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cc2d2a"
      },
      {
        "slug": "cdhr1",
        "symbol": "CDHR1",
        "hgnc": "HGNC:14550",
        "name": "cadherin related family member 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdhr1"
      },
      {
        "slug": "cep164",
        "symbol": "CEP164",
        "hgnc": "HGNC:29182",
        "name": "centrosomal protein 164",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep164"
      },
      {
        "slug": "cerkl",
        "symbol": "CERKL",
        "hgnc": "HGNC:21699",
        "name": "CERK like autophagy regulator",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cerkl"
      },
      {
        "slug": "cfap20",
        "symbol": "CFAP20",
        "hgnc": "HGNC:29523",
        "name": "cilia and flagella associated protein 20",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap20"
      },
      {
        "slug": "cfap418",
        "symbol": "CFAP418",
        "hgnc": "HGNC:27232",
        "name": "cilia and flagella associated protein 418",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap418"
      },
      {
        "slug": "clrn1",
        "symbol": "CLRN1",
        "hgnc": "HGNC:12605",
        "name": "clarin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clrn1"
      },
      {
        "slug": "cnga1",
        "symbol": "CNGA1",
        "hgnc": "HGNC:2148",
        "name": "cyclic nucleotide gated channel subunit alpha 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnga1"
      },
      {
        "slug": "cngb1",
        "symbol": "CNGB1",
        "hgnc": "HGNC:2151",
        "name": "cyclic nucleotide gated channel subunit beta 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cngb1"
      },
      {
        "slug": "coq8b",
        "symbol": "COQ8B",
        "hgnc": "HGNC:19041",
        "name": "coenzyme Q8B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/coq8b"
      },
      {
        "slug": "crb1",
        "symbol": "CRB1",
        "hgnc": "HGNC:2343",
        "name": "crumbs cell polarity complex component 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crb1"
      },
      {
        "slug": "crx",
        "symbol": "CRX",
        "hgnc": "HGNC:2383",
        "name": "cone-rod homeobox",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/crx"
      },
      {
        "slug": "cwc27",
        "symbol": "CWC27",
        "hgnc": "HGNC:10664",
        "name": "CWC27 spliceosome associated cyclophilin",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cwc27"
      },
      {
        "slug": "dhdds",
        "symbol": "DHDDS",
        "hgnc": "HGNC:20603",
        "name": "dehydrodolichyl diphosphate synthase subunit",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/dhdds"
      },
      {
        "slug": "dhx38",
        "symbol": "DHX38",
        "hgnc": "HGNC:17211",
        "name": "DEAH-box helicase 38",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx38"
      },
      {
        "slug": "eys",
        "symbol": "EYS",
        "hgnc": "HGNC:21555",
        "name": "EGF-like photoreceptor maintenance factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eys"
      },
      {
        "slug": "fam161a",
        "symbol": "FAM161A",
        "hgnc": "HGNC:25808",
        "name": "FAM161 centrosomal protein A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam161a"
      },
      {
        "slug": "fscn2",
        "symbol": "FSCN2",
        "hgnc": "HGNC:3960",
        "name": "fascin actin-bundling protein 2, retinal",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fscn2"
      },
      {
        "slug": "fsd1l",
        "symbol": "FSD1L",
        "hgnc": "HGNC:13753",
        "name": "fibronectin type III and SPRY domain containing 1 like",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fsd1l"
      },
      {
        "slug": "guca1b",
        "symbol": "GUCA1B",
        "hgnc": "HGNC:4679",
        "name": "guanylate cyclase activator 1B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/guca1b"
      },
      {
        "slug": "hgsnat",
        "symbol": "HGSNAT",
        "hgnc": "HGNC:26527",
        "name": "heparan-alpha-glucosaminide N-acetyltransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hgsnat"
      },
      {
        "slug": "hkdc1",
        "symbol": "HKDC1",
        "hgnc": "HGNC:23302",
        "name": "hexokinase domain containing 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hkdc1"
      },
      {
        "slug": "idh3a",
        "symbol": "IDH3A",
        "hgnc": "HGNC:5384",
        "name": "isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh3a"
      },
      {
        "slug": "idh3b",
        "symbol": "IDH3B",
        "hgnc": "HGNC:5385",
        "name": "isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh3b"
      },
      {
        "slug": "ift140",
        "symbol": "IFT140",
        "hgnc": "HGNC:29077",
        "name": "intraflagellar transport 140",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift140"
      },
      {
        "slug": "ift172",
        "symbol": "IFT172",
        "hgnc": "HGNC:30391",
        "name": "intraflagellar transport 172",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ift172"
      },
      {
        "slug": "ift43",
        "symbol": "IFT43",
        "hgnc": "HGNC:29669",
        "name": "intraflagellar transport 43",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift43"
      },
      {
        "slug": "ift88",
        "symbol": "IFT88",
        "hgnc": "HGNC:20606",
        "name": "intraflagellar transport 88",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift88"
      },
      {
        "slug": "impdh1",
        "symbol": "IMPDH1",
        "hgnc": "HGNC:6052",
        "name": "inosine monophosphate dehydrogenase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/impdh1"
      },
      {
        "slug": "impg1",
        "symbol": "IMPG1",
        "hgnc": "HGNC:6055",
        "name": "interphotoreceptor matrix proteoglycan 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/impg1"
      },
      {
        "slug": "impg2",
        "symbol": "IMPG2",
        "hgnc": "HGNC:18362",
        "name": "interphotoreceptor matrix proteoglycan 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/impg2"
      },
      {
        "slug": "kiaa1549",
        "symbol": "KIAA1549",
        "hgnc": "HGNC:22219",
        "name": "KIAA1549",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa1549"
      },
      {
        "slug": "kiz",
        "symbol": "KIZ",
        "hgnc": "HGNC:15865",
        "name": "kizuna centrosomal protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiz"
      },
      {
        "slug": "klhl7",
        "symbol": "KLHL7",
        "hgnc": "HGNC:15646",
        "name": "kelch like family member 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl7"
      },
      {
        "slug": "lrat",
        "symbol": "LRAT",
        "hgnc": "HGNC:6685",
        "name": "lecithin retinol acyltransferase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lrat"
      },
      {
        "slug": "mak",
        "symbol": "MAK",
        "hgnc": "HGNC:6816",
        "name": "male germ cell associated kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mak"
      },
      {
        "slug": "mertk",
        "symbol": "MERTK",
        "hgnc": "HGNC:7027",
        "name": "MER proto-oncogene, tyrosine kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mertk"
      },
      {
        "slug": "nek2",
        "symbol": "NEK2",
        "hgnc": "HGNC:7745",
        "name": "NIMA related kinase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek2"
      },
      {
        "slug": "nr2e3",
        "symbol": "NR2E3",
        "hgnc": "HGNC:7974",
        "name": "nuclear receptor subfamily 2 group E member 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr2e3"
      },
      {
        "slug": "ofd1",
        "symbol": "OFD1",
        "hgnc": "HGNC:2567",
        "name": "OFD1 centriole and centriolar satellite protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ofd1"
      },
      {
        "slug": "pcare",
        "symbol": "PCARE",
        "hgnc": "HGNC:34383",
        "name": "photoreceptor cilium actin regulator",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcare"
      },
      {
        "slug": "pde6a",
        "symbol": "PDE6A",
        "hgnc": "HGNC:8785",
        "name": "phosphodiesterase 6A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6a"
      },
      {
        "slug": "pde6b",
        "symbol": "PDE6B",
        "hgnc": "HGNC:8786",
        "name": "phosphodiesterase 6B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6b"
      },
      {
        "slug": "pde6g",
        "symbol": "PDE6G",
        "hgnc": "HGNC:8789",
        "name": "phosphodiesterase 6G",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6g"
      },
      {
        "slug": "pomgnt1",
        "symbol": "POMGNT1",
        "hgnc": "HGNC:19139",
        "name": "protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pomgnt1"
      },
      {
        "slug": "prcd",
        "symbol": "PRCD",
        "hgnc": "HGNC:32528",
        "name": "photoreceptor disc component",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prcd"
      },
      {
        "slug": "prom1",
        "symbol": "PROM1",
        "hgnc": "HGNC:9454",
        "name": "prominin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prom1"
      },
      {
        "slug": "prpf3",
        "symbol": "PRPF3",
        "hgnc": "HGNC:17348",
        "name": "pre-mRNA processing factor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf3"
      },
      {
        "slug": "prpf31",
        "symbol": "PRPF31",
        "hgnc": "HGNC:15446",
        "name": "pre-mRNA processing factor 31",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf31"
      },
      {
        "slug": "prpf6",
        "symbol": "PRPF6",
        "hgnc": "HGNC:15860",
        "name": "pre-mRNA processing factor 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf6"
      },
      {
        "slug": "prpf8",
        "symbol": "PRPF8",
        "hgnc": "HGNC:17340",
        "name": "pre-mRNA processing factor 8",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prpf8"
      },
      {
        "slug": "prph2",
        "symbol": "PRPH2",
        "hgnc": "HGNC:9942",
        "name": "peripherin 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prph2"
      },
      {
        "slug": "rbp3",
        "symbol": "RBP3",
        "hgnc": "HGNC:9921",
        "name": "retinol binding protein 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbp3"
      },
      {
        "slug": "rdh12",
        "symbol": "RDH12",
        "hgnc": "HGNC:19977",
        "name": "retinol dehydrogenase 12",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rdh12"
      },
      {
        "slug": "reep6",
        "symbol": "REEP6",
        "hgnc": "HGNC:30078",
        "name": "receptor accessory protein 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/reep6"
      },
      {
        "slug": "rgr",
        "symbol": "RGR",
        "hgnc": "HGNC:9990",
        "name": "retinal G protein coupled receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rgr"
      },
      {
        "slug": "rho",
        "symbol": "RHO",
        "hgnc": "HGNC:10012",
        "name": "rhodopsin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rho"
      },
      {
        "slug": "rlbp1",
        "symbol": "RLBP1",
        "hgnc": "HGNC:10024",
        "name": "retinaldehyde binding protein 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rlbp1"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "hgnc": "HGNC:10193",
        "name": "RNA, U4 small nuclear 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4-2"
      },
      {
        "slug": "rnu6-1",
        "symbol": "RNU6-1",
        "hgnc": "HGNC:10227",
        "name": "RNA, U6 small nuclear 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-1"
      },
      {
        "slug": "rnu6-2",
        "symbol": "RNU6-2",
        "hgnc": "HGNC:34270",
        "name": "RNA, U6 small nuclear 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-2"
      },
      {
        "slug": "rnu6-8",
        "symbol": "RNU6-8",
        "hgnc": "HGNC:34285",
        "name": "RNA, U6 small nuclear 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-8"
      },
      {
        "slug": "rnu6-9",
        "symbol": "RNU6-9",
        "hgnc": "HGNC:34269",
        "name": "RNA, U6 small nuclear 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-9"
      },
      {
        "slug": "rom1",
        "symbol": "ROM1",
        "hgnc": "HGNC:10254",
        "name": "retinal outer segment membrane protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rom1"
      },
      {
        "slug": "rp1",
        "symbol": "RP1",
        "hgnc": "HGNC:10263",
        "name": "RP1 axonemal microtubule associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp1"
      },
      {
        "slug": "rp1l1",
        "symbol": "RP1L1",
        "hgnc": "HGNC:15946",
        "name": "RP1 like 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp1l1"
      },
      {
        "slug": "rp2",
        "symbol": "RP2",
        "hgnc": "HGNC:10274",
        "name": "RP2 activator of ARL3 GTPase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp2"
      },
      {
        "slug": "rp9",
        "symbol": "RP9",
        "hgnc": "HGNC:10288",
        "name": "RP9 pre-mRNA splicing factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp9"
      },
      {
        "slug": "rpe65",
        "symbol": "RPE65",
        "hgnc": "HGNC:10294",
        "name": "retinoid isomerohydrolase RPE65",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rpe65"
      },
      {
        "slug": "rpgr",
        "symbol": "RPGR",
        "hgnc": "HGNC:10295",
        "name": "retinitis pigmentosa GTPase regulator",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpgr"
      },
      {
        "slug": "rpgrip1",
        "symbol": "RPGRIP1",
        "hgnc": "HGNC:13436",
        "name": "RPGR interacting protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpgrip1"
      },
      {
        "slug": "sag",
        "symbol": "SAG",
        "hgnc": "HGNC:10521",
        "name": "S-antigen visual arrestin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sag"
      },
      {
        "slug": "saxo6",
        "symbol": "SAXO6",
        "hgnc": "HGNC:29917",
        "name": "stabilizer of axonemal microtubules 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/saxo6"
      },
      {
        "slug": "scaper",
        "symbol": "SCAPER",
        "hgnc": "HGNC:13081",
        "name": "S-phase cyclin A associated protein in the ER",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scaper"
      },
      {
        "slug": "sema4a",
        "symbol": "SEMA4A",
        "hgnc": "HGNC:10729",
        "name": "semaphorin 4A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sema4a"
      },
      {
        "slug": "slc7a14",
        "symbol": "SLC7A14",
        "hgnc": "HGNC:29326",
        "name": "solute carrier family 7 member 14",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc7a14"
      },
      {
        "slug": "snrnp200",
        "symbol": "SNRNP200",
        "hgnc": "HGNC:30859",
        "name": "small nuclear ribonucleoprotein U5 subunit 200",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snrnp200"
      },
      {
        "slug": "spata7",
        "symbol": "SPATA7",
        "hgnc": "HGNC:20423",
        "name": "spermatogenesis associated 7",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spata7"
      },
      {
        "slug": "tmem216",
        "symbol": "TMEM216",
        "hgnc": "HGNC:25018",
        "name": "transmembrane protein 216",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem216"
      },
      {
        "slug": "topors",
        "symbol": "TOPORS",
        "hgnc": "HGNC:21653",
        "name": "TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/topors"
      },
      {
        "slug": "ttc8",
        "symbol": "TTC8",
        "hgnc": "HGNC:20087",
        "name": "tetratricopeptide repeat domain 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc8"
      },
      {
        "slug": "tub",
        "symbol": "TUB",
        "hgnc": "HGNC:12406",
        "name": "TUB bipartite transcription factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tub"
      },
      {
        "slug": "tulp1",
        "symbol": "TULP1",
        "hgnc": "HGNC:12423",
        "name": "TUB like protein 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tulp1"
      },
      {
        "slug": "ush2a",
        "symbol": "USH2A",
        "hgnc": "HGNC:12601",
        "name": "usherin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ush2a"
      },
      {
        "slug": "wrn",
        "symbol": "WRN",
        "hgnc": "HGNC:12791",
        "name": "WRN RecQ like helicase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wrn"
      },
      {
        "slug": "znf408",
        "symbol": "ZNF408",
        "hgnc": "HGNC:20041",
        "name": "zinc finger protein 408",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf408"
      },
      {
        "slug": "znf513",
        "symbol": "ZNF513",
        "hgnc": "HGNC:26498",
        "name": "zinc finger protein 513",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf513"
      },
      {
        "slug": "alms1",
        "symbol": "ALMS1",
        "hgnc": "HGNC:428",
        "name": "ALMS1 centrosome and basal body associated protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alms1"
      },
      {
        "slug": "cabp4",
        "symbol": "CABP4",
        "hgnc": "HGNC:1386",
        "name": "calcium binding protein 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cabp4"
      },
      {
        "slug": "cp",
        "symbol": "CP",
        "hgnc": "HGNC:2295",
        "name": "ceruloplasmin",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cp"
      },
      {
        "slug": "dlat",
        "symbol": "DLAT",
        "hgnc": "HGNC:2896",
        "name": "dihydrolipoamide S-acetyltransferase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dlat"
      },
      {
        "slug": "kcnj13",
        "symbol": "KCNJ13",
        "hgnc": "HGNC:6259",
        "name": "potassium inwardly rectifying channel subfamily J member 13",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj13"
      },
      {
        "slug": "lca5",
        "symbol": "LCA5",
        "hgnc": "HGNC:31923",
        "name": "lebercilin LCA5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lca5"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "mmachc",
        "symbol": "MMACHC",
        "hgnc": "HGNC:24525",
        "name": "metabolism of cobalamin associated C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmachc"
      },
      {
        "slug": "mrpl39",
        "symbol": "MRPL39",
        "hgnc": "HGNC:14027",
        "name": "mitochondrial ribosomal protein L39",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mrpl39"
      },
      {
        "slug": "nek8",
        "symbol": "NEK8",
        "hgnc": "HGNC:13387",
        "name": "NIMA related kinase 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek8"
      },
      {
        "slug": "opa1",
        "symbol": "OPA1",
        "hgnc": "HGNC:8140",
        "name": "OPA1 mitochondrial dynamin like GTPase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/opa1"
      },
      {
        "slug": "otx2",
        "symbol": "OTX2",
        "hgnc": "HGNC:8522",
        "name": "orthodenticle homeobox 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/otx2"
      },
      {
        "slug": "zfyve26",
        "symbol": "ZFYVE26",
        "hgnc": "HGNC:20761",
        "name": "zinc finger FYVE-type containing 26",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfyve26"
      },
      {
        "slug": "aars1",
        "symbol": "AARS1",
        "hgnc": "HGNC:20",
        "name": "alanyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/aars1"
      },
      {
        "slug": "cars1",
        "symbol": "CARS1",
        "hgnc": "HGNC:1493",
        "name": "cysteinyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cars1"
      },
      {
        "slug": "dbr1",
        "symbol": "DBR1",
        "hgnc": "HGNC:15594",
        "name": "debranching RNA lariats 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dbr1"
      },
      {
        "slug": "ercc2",
        "symbol": "ERCC2",
        "hgnc": "HGNC:3434",
        "name": "ERCC excision repair 2, TFIIH core complex helicase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc2"
      },
      {
        "slug": "ercc3",
        "symbol": "ERCC3",
        "hgnc": "HGNC:3435",
        "name": "ERCC excision repair 3, TFIIH core complex helicase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc3"
      },
      {
        "slug": "gnb5",
        "symbol": "GNB5",
        "hgnc": "HGNC:4401",
        "name": "G protein subunit beta 5",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gnb5"
      },
      {
        "slug": "gtf2e2",
        "symbol": "GTF2E2",
        "hgnc": "HGNC:4651",
        "name": "general transcription factor IIE subunit 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf2e2"
      },
      {
        "slug": "gtf2h5",
        "symbol": "GTF2H5",
        "hgnc": "HGNC:21157",
        "name": "general transcription factor IIH subunit 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gtf2h5"
      },
      {
        "slug": "hsd17b10",
        "symbol": "HSD17B10",
        "hgnc": "HGNC:4800",
        "name": "hydroxysteroid 17-beta dehydrogenase 10",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hsd17b10"
      },
      {
        "slug": "idua",
        "symbol": "IDUA",
        "hgnc": "HGNC:5391",
        "name": "alpha-L-iduronidase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/idua"
      },
      {
        "slug": "mplkip",
        "symbol": "MPLKIP",
        "hgnc": "HGNC:16002",
        "name": "M-phase specific PLK1 interacting protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mplkip"
      },
      {
        "slug": "rnf113a",
        "symbol": "RNF113A",
        "hgnc": "HGNC:12974",
        "name": "ring finger protein 113A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf113a"
      },
      {
        "slug": "spg11",
        "symbol": "SPG11",
        "hgnc": "HGNC:11226",
        "name": "SPG11 vesicle trafficking associated, spatacsin",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/spg11"
      },
      {
        "slug": "tars1",
        "symbol": "TARS1",
        "hgnc": "HGNC:11572",
        "name": "threonyl-tRNA synthetase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tars1"
      },
      {
        "slug": "tmem67",
        "symbol": "TMEM67",
        "hgnc": "HGNC:28396",
        "name": "transmembrane protein 67",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tmem67"
      },
      {
        "slug": "tnfrsf11b",
        "symbol": "TNFRSF11B",
        "hgnc": "HGNC:11909",
        "name": "TNF receptor superfamily member 11b",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf11b"
      },
      {
        "slug": "wwox",
        "symbol": "WWOX",
        "hgnc": "HGNC:12799",
        "name": "WW domain containing oxidoreductase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wwox"
      },
      {
        "slug": "znf423",
        "symbol": "ZNF423",
        "hgnc": "HGNC:16762",
        "name": "zinc finger protein 423",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf423"
      },
      {
        "slug": "actl6b",
        "symbol": "ACTL6B",
        "hgnc": "HGNC:160",
        "name": "actin like 6B",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/actl6b"
      },
      {
        "slug": "alg6",
        "symbol": "ALG6",
        "hgnc": "HGNC:23157",
        "name": "ALG6 alpha-1,3-glucosyltransferase",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alg6"
      },
      {
        "slug": "ap3b2",
        "symbol": "AP3B2",
        "hgnc": "HGNC:567",
        "name": "adaptor related protein complex 3 subunit beta 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ap3b2"
      },
      {
        "slug": "atp1a2",
        "symbol": "ATP1A2",
        "hgnc": "HGNC:800",
        "name": "ATPase Na+/K+ transporting subunit alpha 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp1a2"
      },
      {
        "slug": "atp1a3",
        "symbol": "ATP1A3",
        "hgnc": "HGNC:801",
        "name": "ATPase Na+/K+ transporting subunit alpha 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp1a3"
      },
      {
        "slug": "atp6v1a",
        "symbol": "ATP6V1A",
        "hgnc": "HGNC:851",
        "name": "ATPase H+ transporting V1 subunit A",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6v1a"
      },
      {
        "slug": "cacna1a",
        "symbol": "CACNA1A",
        "hgnc": "HGNC:1388",
        "name": "calcium voltage-gated channel subunit alpha1 A",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1a"
      },
      {
        "slug": "cacna1b",
        "symbol": "CACNA1B",
        "hgnc": "HGNC:1389",
        "name": "calcium voltage-gated channel subunit alpha1 B",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1b"
      },
      {
        "slug": "cacna2d1",
        "symbol": "CACNA2D1",
        "hgnc": "HGNC:1399",
        "name": "calcium voltage-gated channel auxiliary subunit alpha2delta 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna2d1"
      },
      {
        "slug": "cdk19",
        "symbol": "CDK19",
        "hgnc": "HGNC:19338",
        "name": "cyclin dependent kinase 19",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdk19"
      },
      {
        "slug": "celf2",
        "symbol": "CELF2",
        "hgnc": "HGNC:2550",
        "name": "CUGBP Elav-like family member 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/celf2"
      },
      {
        "slug": "cltc",
        "symbol": "CLTC",
        "hgnc": "HGNC:2092",
        "name": "clathrin heavy chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cltc"
      },
      {
        "slug": "cnksr2",
        "symbol": "CNKSR2",
        "hgnc": "HGNC:19701",
        "name": "connector enhancer of kinase suppressor of Ras 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnksr2"
      },
      {
        "slug": "col4a3",
        "symbol": "COL4A3",
        "hgnc": "HGNC:2204",
        "name": "collagen type IV alpha 3 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a3"
      },
      {
        "slug": "col4a4",
        "symbol": "COL4A4",
        "hgnc": "HGNC:2206",
        "name": "collagen type IV alpha 4 chain",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col4a4"
      },
      {
        "slug": "cyfip2",
        "symbol": "CYFIP2",
        "hgnc": "HGNC:13760",
        "name": "cytoplasmic FMR1 interacting protein 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyfip2"
      },
      {
        "slug": "dalrd3",
        "symbol": "DALRD3",
        "hgnc": "HGNC:25536",
        "name": "DALR anticodon binding domain containing 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dalrd3"
      },
      {
        "slug": "depdc5",
        "symbol": "DEPDC5",
        "hgnc": "HGNC:18423",
        "name": "DEP domain containing 5, GATOR1 subcomplex subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/depdc5"
      },
      {
        "slug": "dnm1",
        "symbol": "DNM1",
        "hgnc": "HGNC:2972",
        "name": "dynamin 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnm1"
      },
      {
        "slug": "eef1a2",
        "symbol": "EEF1A2",
        "hgnc": "HGNC:3192",
        "name": "eukaryotic translation elongation factor 1 alpha 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eef1a2"
      },
      {
        "slug": "ercc6",
        "symbol": "ERCC6",
        "hgnc": "HGNC:3438",
        "name": "ERCC excision repair 6, chromatin remodeling factor",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc6"
      },
      {
        "slug": "ercc8",
        "symbol": "ERCC8",
        "hgnc": "HGNC:3439",
        "name": "ERCC excision repair 8, CSA ubiquitin ligase complex subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc8"
      },
      {
        "slug": "fbxo28",
        "symbol": "FBXO28",
        "hgnc": "HGNC:29046",
        "name": "F-box protein 28",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fbxo28"
      },
      {
        "slug": "fgf12",
        "symbol": "FGF12",
        "hgnc": "HGNC:3668",
        "name": "fibroblast growth factor 12",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgf12"
      },
      {
        "slug": "foxg1",
        "symbol": "FOXG1",
        "hgnc": "HGNC:3811",
        "name": "forkhead box G1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxg1"
      },
      {
        "slug": "fzr1",
        "symbol": "FZR1",
        "hgnc": "HGNC:24824",
        "name": "fizzy and cell division cycle 20 related 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fzr1"
      },
      {
        "slug": "gabbr2",
        "symbol": "GABBR2",
        "hgnc": "HGNC:4507",
        "name": "gamma-aminobutyric acid type B receptor subunit 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabbr2"
      },
      {
        "slug": "gabra2",
        "symbol": "GABRA2",
        "hgnc": "HGNC:4076",
        "name": "gamma-aminobutyric acid type A receptor subunit alpha2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabra2"
      },
      {
        "slug": "gabra5",
        "symbol": "GABRA5",
        "hgnc": "HGNC:4079",
        "name": "gamma-aminobutyric acid type A receptor subunit alpha5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabra5"
      },
      {
        "slug": "gabrb2",
        "symbol": "GABRB2",
        "hgnc": "HGNC:4082",
        "name": "gamma-aminobutyric acid type A receptor subunit beta2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrb2"
      },
      {
        "slug": "gabrg2",
        "symbol": "GABRG2",
        "hgnc": "HGNC:4087",
        "name": "gamma-aminobutyric acid type A receptor subunit gamma2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gabrg2"
      },
      {
        "slug": "grin2d",
        "symbol": "GRIN2D",
        "hgnc": "HGNC:4588",
        "name": "glutamate ionotropic receptor NMDA type subunit 2D",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grin2d"
      },
      {
        "slug": "hcn1",
        "symbol": "HCN1",
        "hgnc": "HGNC:4845",
        "name": "hyperpolarization activated cyclic nucleotide gated potassium channel 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hcn1"
      },
      {
        "slug": "kcna2",
        "symbol": "KCNA2",
        "hgnc": "HGNC:6220",
        "name": "potassium voltage-gated channel subfamily A member 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcna2"
      },
      {
        "slug": "kcnb1",
        "symbol": "KCNB1",
        "hgnc": "HGNC:6231",
        "name": "potassium voltage-gated channel subfamily B member 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnb1"
      },
      {
        "slug": "kcnc2",
        "symbol": "KCNC2",
        "hgnc": "HGNC:6234",
        "name": "potassium voltage-gated channel subfamily C member 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnc2"
      },
      {
        "slug": "kcnh5",
        "symbol": "KCNH5",
        "hgnc": "HGNC:6254",
        "name": "potassium voltage-gated channel subfamily H member 5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnh5"
      },
      {
        "slug": "mdga2",
        "symbol": "MDGA2",
        "hgnc": "HGNC:19835",
        "name": "MAM domain containing glycosylphosphatidylinositol anchor 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mdga2"
      },
      {
        "slug": "necap1",
        "symbol": "NECAP1",
        "hgnc": "HGNC:24539",
        "name": "NECAP endocytosis associated 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/necap1"
      },
      {
        "slug": "ntrk2",
        "symbol": "NTRK2",
        "hgnc": "HGNC:8032",
        "name": "neurotrophic receptor tyrosine kinase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ntrk2"
      },
      {
        "slug": "nus1",
        "symbol": "NUS1",
        "hgnc": "HGNC:21042",
        "name": "NUS1 dehydrodolichyl diphosphate synthase subunit",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nus1"
      },
      {
        "slug": "pacs2",
        "symbol": "PACS2",
        "hgnc": "HGNC:23794",
        "name": "phosphofurin acidic cluster sorting protein 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pacs2"
      },
      {
        "slug": "pars2",
        "symbol": "PARS2",
        "hgnc": "HGNC:30563",
        "name": "prolyl-tRNA synthetase 2, mitochondrial",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pars2"
      },
      {
        "slug": "ppp3ca",
        "symbol": "PPP3CA",
        "hgnc": "HGNC:9314",
        "name": "protein phosphatase 3 catalytic subunit alpha",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppp3ca"
      },
      {
        "slug": "scn1a",
        "symbol": "SCN1A",
        "hgnc": "HGNC:10585",
        "name": "sodium voltage-gated channel alpha subunit 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn1a"
      },
      {
        "slug": "scn3a",
        "symbol": "SCN3A",
        "hgnc": "HGNC:10590",
        "name": "sodium voltage-gated channel alpha subunit 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn3a"
      },
      {
        "slug": "scn8a",
        "symbol": "SCN8A",
        "hgnc": "HGNC:10596",
        "name": "sodium voltage-gated channel alpha subunit 8",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn8a"
      },
      {
        "slug": "slc13a5",
        "symbol": "SLC13A5",
        "hgnc": "HGNC:23089",
        "name": "solute carrier family 13 member 5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc13a5"
      },
      {
        "slug": "slc1a2",
        "symbol": "SLC1A2",
        "hgnc": "HGNC:10940",
        "name": "solute carrier family 1 member 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc1a2"
      },
      {
        "slug": "slc38a3",
        "symbol": "SLC38A3",
        "hgnc": "HGNC:18044",
        "name": "solute carrier family 38 member 3",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc38a3"
      },
      {
        "slug": "syngap1",
        "symbol": "SYNGAP1",
        "hgnc": "HGNC:11497",
        "name": "synaptic Ras GTPase activating protein 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/syngap1"
      },
      {
        "slug": "synj1",
        "symbol": "SYNJ1",
        "hgnc": "HGNC:11503",
        "name": "synaptojanin 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/synj1"
      },
      {
        "slug": "szt2",
        "symbol": "SZT2",
        "hgnc": "HGNC:29040",
        "name": "SZT2 subunit of KICSTOR complex",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/szt2"
      },
      {
        "slug": "trak1",
        "symbol": "TRAK1",
        "hgnc": "HGNC:29947",
        "name": "trafficking kinesin protein 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trak1"
      },
      {
        "slug": "uba5",
        "symbol": "UBA5",
        "hgnc": "HGNC:23230",
        "name": "ubiquitin like modifier activating enzyme 5",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uba5"
      },
      {
        "slug": "ufsp2",
        "symbol": "UFSP2",
        "hgnc": "HGNC:25640",
        "name": "UFM1 specific peptidase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufsp2"
      },
      {
        "slug": "ywhag",
        "symbol": "YWHAG",
        "hgnc": "HGNC:12852",
        "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ywhag"
      },
      {
        "slug": "apob",
        "symbol": "APOB",
        "hgnc": "HGNC:603",
        "name": "apolipoprotein B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apob"
      },
      {
        "slug": "bbs4",
        "symbol": "BBS4",
        "hgnc": "HGNC:969",
        "name": "Bardet-Biedl syndrome 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs4"
      },
      {
        "slug": "c1qtnf5",
        "symbol": "C1QTNF5",
        "hgnc": "HGNC:14344",
        "name": "C1q and TNF related 5",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c1qtnf5"
      },
      {
        "slug": "cfap410",
        "symbol": "CFAP410",
        "hgnc": "HGNC:1260",
        "name": "cilia and flagella associated protein 410",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap410"
      },
      {
        "slug": "clcc1",
        "symbol": "CLCC1",
        "hgnc": "HGNC:29675",
        "name": "chloride channel CLIC like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcc1"
      },
      {
        "slug": "cln5",
        "symbol": "CLN5",
        "hgnc": "HGNC:2076",
        "name": "CLN5 lysosomal BMP synthase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cln5"
      },
      {
        "slug": "cln6",
        "symbol": "CLN6",
        "hgnc": "HGNC:2077",
        "name": "CLN6 transmembrane ER protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cln6"
      },
      {
        "slug": "ctnnb1",
        "symbol": "CTNNB1",
        "hgnc": "HGNC:2514",
        "name": "catenin beta 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnb1"
      },
      {
        "slug": "cyp4v2",
        "symbol": "CYP4V2",
        "hgnc": "HGNC:23198",
        "name": "cytochrome P450 family 4 subfamily V member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp4v2"
      },
      {
        "slug": "gnptab",
        "symbol": "GNPTAB",
        "hgnc": "HGNC:29670",
        "name": "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnptab"
      },
      {
        "slug": "mab21l1",
        "symbol": "MAB21L1",
        "hgnc": "HGNC:6757",
        "name": "mab-21 like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mab21l1"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2b1"
      },
      {
        "slug": "mcoln1",
        "symbol": "MCOLN1",
        "hgnc": "HGNC:13356",
        "name": "mucolipin TRP cation channel 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mcoln1"
      },
      {
        "slug": "mttp",
        "symbol": "MTTP",
        "hgnc": "HGNC:7467",
        "name": "microsomal triglyceride transfer protein",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mttp"
      },
      {
        "slug": "pank2",
        "symbol": "PANK2",
        "hgnc": "HGNC:15894",
        "name": "pantothenate kinase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pank2"
      },
      {
        "slug": "pex7",
        "symbol": "PEX7",
        "hgnc": "HGNC:8860",
        "name": "peroxisomal biogenesis factor 7",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex7"
      },
      {
        "slug": "phyh",
        "symbol": "PHYH",
        "hgnc": "HGNC:8940",
        "name": "phytanoyl-CoA 2-hydroxylase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phyh"
      },
      {
        "slug": "pisd",
        "symbol": "PISD",
        "hgnc": "HGNC:8999",
        "name": "phosphatidylserine decarboxylase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pisd"
      },
      {
        "slug": "ppt1",
        "symbol": "PPT1",
        "hgnc": "HGNC:9325",
        "name": "palmitoyl-protein thioesterase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppt1"
      },
      {
        "slug": "rs1",
        "symbol": "RS1",
        "hgnc": "HGNC:10457",
        "name": "retinoschisin 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rs1"
      },
      {
        "slug": "sdccag8",
        "symbol": "SDCCAG8",
        "hgnc": "HGNC:10671",
        "name": "SHH signaling and ciliogenesis regulator SDCCAG8",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sdccag8"
      },
      {
        "slug": "slc19a2",
        "symbol": "SLC19A2",
        "hgnc": "HGNC:10938",
        "name": "solute carrier family 19 member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc19a2"
      },
      {
        "slug": "sumf1",
        "symbol": "SUMF1",
        "hgnc": "HGNC:20376",
        "name": "sulfatase modifying factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sumf1"
      },
      {
        "slug": "tpp1",
        "symbol": "TPP1",
        "hgnc": "HGNC:2073",
        "name": "tripeptidyl peptidase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tpp1"
      },
      {
        "slug": "tubb4b",
        "symbol": "TUBB4B",
        "hgnc": "HGNC:20771",
        "name": "tubulin beta 4B class IVb",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tubb4b"
      },
      {
        "slug": "usp45",
        "symbol": "USP45",
        "hgnc": "HGNC:20080",
        "name": "ubiquitin specific peptidase 45",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp45"
      }
    ]
  }
}