{
  "url": "https://dantelabs.com/traits/platyspondyly",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "platyspondyly",
    "id": "HP:0000926",
    "name": "Flattened vertebrae",
    "label": "Platyspondyly",
    "definition": "A flattened vertebral body shape with reduced distance between the vertebral endplates.",
    "synonyms": [
      "Flat vertebral bodies",
      "Flattened vertebral bodies"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-vertebral-body-morphology",
        "name": "Abnormal vertebral body morphology",
        "url": "https://dantelabs.com/traits/abnormal-vertebral-body-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "severe-platyspondyly",
        "name": "Severe platyspondyly",
        "genes": 8,
        "url": "https://dantelabs.com/traits/severe-platyspondyly"
      },
      {
        "slug": "thoracic-platyspondyly",
        "name": "Thoracic platyspondyly",
        "genes": 6,
        "url": "https://dantelabs.com/traits/thoracic-platyspondyly"
      },
      {
        "slug": "cervical-platyspondyly",
        "name": "Cervical platyspondyly",
        "genes": 4,
        "url": "https://dantelabs.com/traits/cervical-platyspondyly"
      },
      {
        "slug": "biconcave-flattened-vertebrae",
        "name": "Biconcave flattened vertebrae",
        "genes": 2,
        "url": "https://dantelabs.com/traits/biconcave-flattened-vertebrae"
      },
      {
        "slug": "supernumerary-vertebral-ossification-centers",
        "name": "Supernumerary vertebral ossification centers",
        "genes": 2,
        "url": "https://dantelabs.com/traits/supernumerary-vertebral-ossification-centers"
      },
      {
        "slug": "lumbar-platyspondyly",
        "name": "Lumbar platyspondyly",
        "genes": 1,
        "url": "https://dantelabs.com/traits/lumbar-platyspondyly"
      },
      {
        "slug": "squared-off-platyspondyly",
        "name": "Squared-off platyspondyly",
        "genes": 1,
        "url": "https://dantelabs.com/traits/squared-off-platyspondyly"
      }
    ],
    "genes": [
      {
        "slug": "arsk",
        "symbol": "ARSK",
        "hgnc": "HGNC:25239",
        "name": "arylsulfatase family member K",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arsk"
      },
      {
        "slug": "b3galt6",
        "symbol": "B3GALT6",
        "hgnc": "HGNC:17978",
        "name": "beta-1,3-galactosyltransferase 6",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/b3galt6"
      },
      {
        "slug": "bgn",
        "symbol": "BGN",
        "hgnc": "HGNC:1044",
        "name": "biglycan",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bgn"
      },
      {
        "slug": "bmp1",
        "symbol": "BMP1",
        "hgnc": "HGNC:1067",
        "name": "bone morphogenetic protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bmp1"
      },
      {
        "slug": "bnip1",
        "symbol": "BNIP1",
        "hgnc": "HGNC:1082",
        "name": "BCL2 interacting protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bnip1"
      },
      {
        "slug": "cant1",
        "symbol": "CANT1",
        "hgnc": "HGNC:19721",
        "name": "calcium activated nucleotidase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cant1"
      },
      {
        "slug": "col11a2",
        "symbol": "COL11A2",
        "hgnc": "HGNC:2187",
        "name": "collagen type XI alpha 2 chain",
        "frequency": "obligate",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/col11a2"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "obligate",
        "diseases": 18,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "creb3l1",
        "symbol": "CREB3L1",
        "hgnc": "HGNC:18856",
        "name": "cAMP responsive element binding protein 3 like 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/creb3l1"
      },
      {
        "slug": "csf1r",
        "symbol": "CSF1R",
        "hgnc": "HGNC:2433",
        "name": "colony stimulating factor 1 receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/csf1r"
      },
      {
        "slug": "ddr2",
        "symbol": "DDR2",
        "hgnc": "HGNC:2731",
        "name": "discoidin domain receptor tyrosine kinase 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ddr2"
      },
      {
        "slug": "dna2",
        "symbol": "DNA2",
        "hgnc": "HGNC:2939",
        "name": "DNA replication helicase/nuclease 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dna2"
      },
      {
        "slug": "dym",
        "symbol": "DYM",
        "hgnc": "HGNC:21317",
        "name": "dymeclin",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/dym"
      },
      {
        "slug": "eri1",
        "symbol": "ERI1",
        "hgnc": "HGNC:23994",
        "name": "exoribonuclease 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eri1"
      },
      {
        "slug": "extl3",
        "symbol": "EXTL3",
        "hgnc": "HGNC:3518",
        "name": "exostosin like glycosyltransferase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/extl3"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "frequency": "obligate",
        "diseases": 5,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "glb1",
        "symbol": "GLB1",
        "hgnc": "HGNC:4298",
        "name": "galactosidase beta 1",
        "frequency": "obligate",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/glb1"
      },
      {
        "slug": "gnpnat1",
        "symbol": "GNPNAT1",
        "hgnc": "HGNC:19980",
        "name": "glucosamine-phosphate N-acetyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnpnat1"
      },
      {
        "slug": "ift43",
        "symbol": "IFT43",
        "hgnc": "HGNC:29669",
        "name": "intraflagellar transport 43",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift43"
      },
      {
        "slug": "lama5",
        "symbol": "LAMA5",
        "hgnc": "HGNC:6485",
        "name": "laminin subunit alpha 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lama5"
      },
      {
        "slug": "lbr",
        "symbol": "LBR",
        "hgnc": "HGNC:6518",
        "name": "lamin B receptor",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/lbr"
      },
      {
        "slug": "lrp5",
        "symbol": "LRP5",
        "hgnc": "HGNC:6697",
        "name": "LDL receptor related protein 5",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lrp5"
      },
      {
        "slug": "mia3",
        "symbol": "MIA3",
        "hgnc": "HGNC:24008",
        "name": "MIA SH3 domain ER export factor 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mia3"
      },
      {
        "slug": "mrps28",
        "symbol": "MRPS28",
        "hgnc": "HGNC:14513",
        "name": "mitochondrial ribosomal protein S28",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mrps28"
      },
      {
        "slug": "pcyt1a",
        "symbol": "PCYT1A",
        "hgnc": "HGNC:8754",
        "name": "phosphate cytidylyltransferase 1A, choline",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pcyt1a"
      },
      {
        "slug": "plod1",
        "symbol": "PLOD1",
        "hgnc": "HGNC:9081",
        "name": "procollagen-lysine,2-oxoglutarate 5-dioxygenase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plod1"
      },
      {
        "slug": "plod3",
        "symbol": "PLOD3",
        "hgnc": "HGNC:9083",
        "name": "procollagen-lysine,2-oxoglutarate 5-dioxygenase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plod3"
      },
      {
        "slug": "prkg2",
        "symbol": "PRKG2",
        "hgnc": "HGNC:9416",
        "name": "protein kinase cGMP-dependent 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prkg2"
      },
      {
        "slug": "rab33b",
        "symbol": "RAB33B",
        "hgnc": "HGNC:16075",
        "name": "RAB33B, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab33b"
      },
      {
        "slug": "rpl13",
        "symbol": "RPL13",
        "hgnc": "HGNC:10303",
        "name": "ribosomal protein L13",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rpl13"
      },
      {
        "slug": "rspry1",
        "symbol": "RSPRY1",
        "hgnc": "HGNC:29420",
        "name": "ring finger and SPRY domain containing 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rspry1"
      },
      {
        "slug": "serpinh1",
        "symbol": "SERPINH1",
        "hgnc": "HGNC:1546",
        "name": "serpin family H member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/serpinh1"
      },
      {
        "slug": "slc13a1",
        "symbol": "SLC13A1",
        "hgnc": "HGNC:10916",
        "name": "solute carrier family 13 member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc13a1"
      },
      {
        "slug": "slc35d1",
        "symbol": "SLC35D1",
        "hgnc": "HGNC:20800",
        "name": "solute carrier family 35 member D1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc35d1"
      },
      {
        "slug": "tmem53",
        "symbol": "TMEM53",
        "hgnc": "HGNC:26186",
        "name": "transmembrane protein 53",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem53"
      },
      {
        "slug": "tomm7",
        "symbol": "TOMM7",
        "hgnc": "HGNC:21648",
        "name": "translocase of outer mitochondrial membrane 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tomm7"
      },
      {
        "slug": "trappc2",
        "symbol": "TRAPPC2",
        "hgnc": "HGNC:23068",
        "name": "trafficking protein particle complex subunit 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trappc2"
      },
      {
        "slug": "trpv4",
        "symbol": "TRPV4",
        "hgnc": "HGNC:18083",
        "name": "transient receptor potential cation channel subfamily V member 4",
        "frequency": "obligate",
        "diseases": 6,
        "url": "https://dantelabs.com/genes/trpv4"
      },
      {
        "slug": "xylt2",
        "symbol": "XYLT2",
        "hgnc": "HGNC:15517",
        "name": "xylosyltransferase 2",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/xylt2"
      },
      {
        "slug": "acan",
        "symbol": "ACAN",
        "hgnc": "HGNC:319",
        "name": "aggrecan",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/acan"
      },
      {
        "slug": "acp5",
        "symbol": "ACP5",
        "hgnc": "HGNC:124",
        "name": "acid phosphatase 5, tartrate resistant",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/acp5"
      },
      {
        "slug": "ccn6",
        "symbol": "CCN6",
        "hgnc": "HGNC:12771",
        "name": "cellular communication network factor 6",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ccn6"
      },
      {
        "slug": "cog4",
        "symbol": "COG4",
        "hgnc": "HGNC:18620",
        "name": "component of oligomeric golgi complex 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cog4"
      },
      {
        "slug": "comp",
        "symbol": "COMP",
        "hgnc": "HGNC:2227",
        "name": "cartilage oligomeric matrix protein",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/comp"
      },
      {
        "slug": "gpx4",
        "symbol": "GPX4",
        "hgnc": "HGNC:4556",
        "name": "glutathione peroxidase 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gpx4"
      },
      {
        "slug": "hdac6",
        "symbol": "HDAC6",
        "hgnc": "HGNC:14064",
        "name": "histone deacetylase 6",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hdac6"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "rmp64",
        "symbol": "RMP64",
        "hgnc": "HGNC:24496",
        "name": "ribonuclease MRP subunit p64",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rmp64"
      },
      {
        "slug": "slc29a3",
        "symbol": "SLC29A3",
        "hgnc": "HGNC:23096",
        "name": "solute carrier family 29 member 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc29a3"
      },
      {
        "slug": "smad4",
        "symbol": "SMAD4",
        "hgnc": "HGNC:6770",
        "name": "SMAD family member 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/smad4"
      },
      {
        "slug": "tcirg1",
        "symbol": "TCIRG1",
        "hgnc": "HGNC:11647",
        "name": "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tcirg1"
      },
      {
        "slug": "tnfrsf11a",
        "symbol": "TNFRSF11A",
        "hgnc": "HGNC:11908",
        "name": "TNF receptor superfamily member 11a",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf11a"
      },
      {
        "slug": "tonsl",
        "symbol": "TONSL",
        "hgnc": "HGNC:7801",
        "name": "tonsoku like, DNA repair protein",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tonsl"
      },
      {
        "slug": "trip11",
        "symbol": "TRIP11",
        "hgnc": "HGNC:12305",
        "name": "thyroid hormone receptor interactor 11",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/trip11"
      },
      {
        "slug": "abcc9",
        "symbol": "ABCC9",
        "hgnc": "HGNC:60",
        "name": "ATP binding cassette subfamily C member 9",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/abcc9"
      },
      {
        "slug": "adamtsl2",
        "symbol": "ADAMTSL2",
        "hgnc": "HGNC:14631",
        "name": "ADAMTS like 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adamtsl2"
      },
      {
        "slug": "atp7a",
        "symbol": "ATP7A",
        "hgnc": "HGNC:869",
        "name": "ATPase copper transporting alpha",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/atp7a"
      },
      {
        "slug": "ccn2",
        "symbol": "CCN2",
        "hgnc": "HGNC:2500",
        "name": "cellular communication network factor 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ccn2"
      },
      {
        "slug": "ddrgk1",
        "symbol": "DDRGK1",
        "hgnc": "HGNC:16110",
        "name": "DDRGK domain containing 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ddrgk1"
      },
      {
        "slug": "hspg2",
        "symbol": "HSPG2",
        "hgnc": "HGNC:5273",
        "name": "heparan sulfate proteoglycan 2",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/hspg2"
      },
      {
        "slug": "idh1",
        "symbol": "IDH1",
        "hgnc": "HGNC:5382",
        "name": "isocitrate dehydrogenase (NADP(+)) 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh1"
      },
      {
        "slug": "kcnj8",
        "symbol": "KCNJ8",
        "hgnc": "HGNC:6269",
        "name": "potassium inwardly rectifying channel subfamily J member 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnj8"
      },
      {
        "slug": "kif22",
        "symbol": "KIF22",
        "hgnc": "HGNC:6391",
        "name": "kinesin family member 22",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif22"
      },
      {
        "slug": "rint1",
        "symbol": "RINT1",
        "hgnc": "HGNC:21876",
        "name": "RAD50 interactor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rint1"
      },
      {
        "slug": "rmrp",
        "symbol": "RMRP",
        "hgnc": "HGNC:10031",
        "name": "RNA component of mitochondrial RNA processing endoribonuclease",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rmrp"
      },
      {
        "slug": "slc39a13",
        "symbol": "SLC39A13",
        "hgnc": "HGNC:20859",
        "name": "solute carrier family 39 member 13",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/slc39a13"
      },
      {
        "slug": "smarcal1",
        "symbol": "SMARCAL1",
        "hgnc": "HGNC:11102",
        "name": "SNF2 related chromatin remodeling annealing helicase 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/smarcal1"
      },
      {
        "slug": "sparc",
        "symbol": "SPARC",
        "hgnc": "HGNC:11219",
        "name": "secreted protein acidic and cysteine rich",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sparc"
      },
      {
        "slug": "b3gat3",
        "symbol": "B3GAT3",
        "hgnc": "HGNC:923",
        "name": "beta-1,3-glucuronyltransferase 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/b3gat3"
      },
      {
        "slug": "chst3",
        "symbol": "CHST3",
        "hgnc": "HGNC:1971",
        "name": "carbohydrate sulfotransferase 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chst3"
      },
      {
        "slug": "col10a1",
        "symbol": "COL10A1",
        "hgnc": "HGNC:2185",
        "name": "collagen type X alpha 1 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col10a1"
      },
      {
        "slug": "col11a1",
        "symbol": "COL11A1",
        "hgnc": "HGNC:2186",
        "name": "collagen type XI alpha 1 chain",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col11a1"
      },
      {
        "slug": "col9a1",
        "symbol": "COL9A1",
        "hgnc": "HGNC:2217",
        "name": "collagen type IX alpha 1 chain",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/col9a1"
      },
      {
        "slug": "col9a2",
        "symbol": "COL9A2",
        "hgnc": "HGNC:2218",
        "name": "collagen type IX alpha 2 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col9a2"
      },
      {
        "slug": "col9a3",
        "symbol": "COL9A3",
        "hgnc": "HGNC:2219",
        "name": "collagen type IX alpha 3 chain",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col9a3"
      },
      {
        "slug": "fkbp10",
        "symbol": "FKBP10",
        "hgnc": "HGNC:18169",
        "name": "FKBP prolyl isomerase 10",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fkbp10"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "fn1",
        "symbol": "FN1",
        "hgnc": "HGNC:3778",
        "name": "fibronectin 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fn1"
      },
      {
        "slug": "gorab",
        "symbol": "GORAB",
        "hgnc": "HGNC:25676",
        "name": "golgin, RAB6 interacting",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gorab"
      },
      {
        "slug": "ifitm5",
        "symbol": "IFITM5",
        "hgnc": "HGNC:16644",
        "name": "interferon induced transmembrane protein 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ifitm5"
      },
      {
        "slug": "kdelr2",
        "symbol": "KDELR2",
        "hgnc": "HGNC:6305",
        "name": "KDEL endoplasmic reticulum protein retention receptor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kdelr2"
      },
      {
        "slug": "loxl3",
        "symbol": "LOXL3",
        "hgnc": "HGNC:13869",
        "name": "lysyl oxidase like 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/loxl3"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/man2b1"
      },
      {
        "slug": "mbtps2",
        "symbol": "MBTPS2",
        "hgnc": "HGNC:15455",
        "name": "membrane bound transcription factor peptidase, site 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mbtps2"
      },
      {
        "slug": "ocrl",
        "symbol": "OCRL",
        "hgnc": "HGNC:8108",
        "name": "OCRL inositol polyphosphate-5-phosphatase",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ocrl"
      },
      {
        "slug": "plod2",
        "symbol": "PLOD2",
        "hgnc": "HGNC:9082",
        "name": "procollagen-lysine,2-oxoglutarate 5-dioxygenase 2",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/plod2"
      },
      {
        "slug": "pycr1",
        "symbol": "PYCR1",
        "hgnc": "HGNC:9721",
        "name": "pyrroline-5-carboxylate reductase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pycr1"
      },
      {
        "slug": "rnu4atac",
        "symbol": "RNU4ATAC",
        "hgnc": "HGNC:34016",
        "name": "RNA, U4atac small nuclear",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rnu4atac"
      },
      {
        "slug": "sfrp4",
        "symbol": "SFRP4",
        "hgnc": "HGNC:10778",
        "name": "secreted frizzled related protein 4",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sfrp4"
      },
      {
        "slug": "xylt1",
        "symbol": "XYLT1",
        "hgnc": "HGNC:15516",
        "name": "xylosyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xylt1"
      },
      {
        "slug": "zfx",
        "symbol": "ZFX",
        "hgnc": "HGNC:12869",
        "name": "zinc finger protein X-linked",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zfx"
      },
      {
        "slug": "nek1",
        "symbol": "NEK1",
        "hgnc": "HGNC:7744",
        "name": "NIMA related kinase 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek1"
      },
      {
        "slug": "pmm2",
        "symbol": "PMM2",
        "hgnc": "HGNC:9115",
        "name": "phosphomannomutase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pmm2"
      },
      {
        "slug": "sgms2",
        "symbol": "SGMS2",
        "hgnc": "HGNC:28395",
        "name": "sphingomyelin synthase 2",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sgms2"
      },
      {
        "slug": "ada",
        "symbol": "ADA",
        "hgnc": "HGNC:186",
        "name": "adenosine deaminase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ada"
      },
      {
        "slug": "aga",
        "symbol": "AGA",
        "hgnc": "HGNC:318",
        "name": "aspartylglucosaminidase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aga"
      },
      {
        "slug": "aifm1",
        "symbol": "AIFM1",
        "hgnc": "HGNC:8768",
        "name": "apoptosis inducing factor mitochondria associated 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aifm1"
      },
      {
        "slug": "alpl",
        "symbol": "ALPL",
        "hgnc": "HGNC:438",
        "name": "alkaline phosphatase, biomineralization associated",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alpl"
      },
      {
        "slug": "cfap410",
        "symbol": "CFAP410",
        "hgnc": "HGNC:1260",
        "name": "cilia and flagella associated protein 410",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap410"
      },
      {
        "slug": "col1a1",
        "symbol": "COL1A1",
        "hgnc": "HGNC:2197",
        "name": "collagen type I alpha 1 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a1"
      },
      {
        "slug": "col1a2",
        "symbol": "COL1A2",
        "hgnc": "HGNC:2198",
        "name": "collagen type I alpha 2 chain",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/col1a2"
      },
      {
        "slug": "eif2ak3",
        "symbol": "EIF2AK3",
        "hgnc": "HGNC:3255",
        "name": "eukaryotic translation initiation factor 2 alpha kinase 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif2ak3"
      },
      {
        "slug": "exoc6b",
        "symbol": "EXOC6B",
        "hgnc": "HGNC:17085",
        "name": "exocyst complex component 6B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/exoc6b"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "flna",
        "symbol": "FLNA",
        "hgnc": "HGNC:3754",
        "name": "filamin A",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flna"
      },
      {
        "slug": "galns",
        "symbol": "GALNS",
        "hgnc": "HGNC:4122",
        "name": "galactosamine (N-acetyl)-6-sulfatase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/galns"
      },
      {
        "slug": "gusb",
        "symbol": "GUSB",
        "hgnc": "HGNC:4696",
        "name": "glucuronidase beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gusb"
      },
      {
        "slug": "ltbp3",
        "symbol": "LTBP3",
        "hgnc": "HGNC:6716",
        "name": "latent transforming growth factor beta binding protein 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ltbp3"
      },
      {
        "slug": "matn3",
        "symbol": "MATN3",
        "hgnc": "HGNC:6909",
        "name": "matrilin 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/matn3"
      },
      {
        "slug": "mmp13",
        "symbol": "MMP13",
        "hgnc": "HGNC:7159",
        "name": "matrix metallopeptidase 13",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mmp13"
      },
      {
        "slug": "nans",
        "symbol": "NANS",
        "hgnc": "HGNC:19237",
        "name": "N-acetylneuraminate synthase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nans"
      },
      {
        "slug": "p3h1",
        "symbol": "P3H1",
        "hgnc": "HGNC:19316",
        "name": "prolyl 3-hydroxylase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/p3h1"
      },
      {
        "slug": "papss2",
        "symbol": "PAPSS2",
        "hgnc": "HGNC:8604",
        "name": "3'-phosphoadenosine 5'-phosphosulfate synthase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/papss2"
      },
      {
        "slug": "ppib",
        "symbol": "PPIB",
        "hgnc": "HGNC:9255",
        "name": "peptidylprolyl isomerase B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ppib"
      },
      {
        "slug": "runx2",
        "symbol": "RUNX2",
        "hgnc": "HGNC:10472",
        "name": "RUNX family transcription factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/runx2"
      },
      {
        "slug": "sec24d",
        "symbol": "SEC24D",
        "hgnc": "HGNC:10706",
        "name": "SEC24 homolog D, COPII component",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sec24d"
      },
      {
        "slug": "slc25a24",
        "symbol": "SLC25A24",
        "hgnc": "HGNC:20662",
        "name": "solute carrier family 25 member 24",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc25a24"
      },
      {
        "slug": "slc26a2",
        "symbol": "SLC26A2",
        "hgnc": "HGNC:10994",
        "name": "solute carrier family 26 member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc26a2"
      },
      {
        "slug": "tapt1",
        "symbol": "TAPT1",
        "hgnc": "HGNC:26887",
        "name": "transmembrane anterior posterior transformation 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tapt1"
      },
      {
        "slug": "ufsp2",
        "symbol": "UFSP2",
        "hgnc": "HGNC:25640",
        "name": "UFM1 specific peptidase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ufsp2"
      },
      {
        "slug": "wnt1",
        "symbol": "WNT1",
        "hgnc": "HGNC:12774",
        "name": "Wnt family member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wnt1"
      }
    ]
  }
}